Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide

CAS No.
1185388-35-5
Chemical Name:
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide
Synonyms
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide
CBNumber:
CB99740371
Molecular Formula:
C19H15ClN4O2
Molecular Weight:
366.8
MDL Number:
MFCD32012253
MOL File:
1185388-35-5.mol
MSDS File:
SDS
Last updated:2026-04-21 11:20:27

Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Properties

Melting point 172-174 °C
Boiling point 588.0±60.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
pka 2.32±0.10(Predicted)

Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Chemical Properties, Uses, Production

Description

A110 is a potent and selective inhibitor of IMPDHs. A110 binds to the NAD(+) cofactor site and forms a ternary complex with IMP.

Uses

A110 is the inhibitor for Cryptosporidium parvum inosine monophosphate dehydrogenase (CpIMPDH). A110 inhibits CpIMPDH in Toxoplasma gondii with IC50 of 18 nM. A110 exhibits pro-parasitic efficacy and cause parasitemia[1].

References

[1] Gorla SK, et al., Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. Antimicrob Agents Chemother. 2014;58(3):1603-14. DOI:10.1128/AAC.02075-13

Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
A110 pictures 2026-04-21 A110
1185388-35-5
$1520.00-2500.00 10g TargetMol Chemicals Inc.
  • A110 pictures
  • A110
    1185388-35-5
  • $1520.00-2500.00
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Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide 1185388-35-5