Nonapeptide-1
Nonapeptide-1 物理性質
- 比重(密度) :
- 1.38±0.1 g/cm3(Predicted)
- 溶解性:
- soluble in water(≥0.1g/ml)
- 酸解離定数(Pka):
- 13.32±0.46(Predicted)
- 外見 :
- Solid
- 色:
- white or off-white powder
- シーケンス:
- Met-Pro-Phe-Arg-Trp-Phe-Lys-Pro-Val-NH2
- 化粧品成分の機能:
- スキンコンディショニング
ヘアコンディショニング
- InChIKey:
- KNFLNGRLKALWRF-LDXSYGEZSA-N
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
|
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
|
| 注意書き |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P305+P351+P338 |
眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
Nonapeptide-1 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
Nonapeptide-1 化学特性,用途語,生産方法
説明
Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.
定義
Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.
生物学の機能
1. Inhibit melanin synthesis by interfering with the action of tyrosinase in melanocytes. Reduce hyperpigmentation and lighten darker areas that have been damaged by the sun and certain diseases.2. Interfer with melanocyte stimulating hormone (MSH). MSH increases during pregnancy, as a result of certain medical conditions (e.g. diabetes, Addison’s disease), and as a result of excessive sun exposure.3. Nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin in fungi.4. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43%
生物学的応用
Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree[1].
副作用
May cause drowsiness, dizziness, hypotension, or a headache as side-effects when using Nonapeptide-1 Topical medicine. Patients not drink alcohol with medicines as alcohol intensifies drowsiness side-effects.
Nonapeptide-1 上流と下流の製品情報
原材料
準備製品
Nonapeptide-1 生産企業
Global( 356)Suppliers
158563-45-2()キーワード:
- 158563-45-2
- L-Methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide
- Melanostatine-5(nonpeptide-1)
- Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
- Melitane / Nonapeptide-1
- Nonapeptide-1, Melanostatine-5, Melanostatine
- Melitan
- Melanostatine-5, Nonapeptide-1
- Nonapeptide-1/Melitane/Melanostatine
- Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-
- L-Valinamide, L-methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-
- Cosmetics peptide Nonapeptide-1 powder
- Nonapeptide-1(Melanostatine-5)
- Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2 USP/EP/BP
- hexapeptide-2/Dermostatyl
- superior quality Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2 CAS 158563-45-2
- NONAPEPTIDE-1
- CAS 158563-45-2 Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
- Metanostatine-5
- (Met?,Pro?,D-Phe?,D-Trp?,Phe1?)-α-MSH (5-13)
- (Met?,Pro?,D-Phe?,D-Trp?,Phe??)-α-MSH (5-13)
- Jiupeptide-1
- Neptide-1
- ArkTide N91
- Bright-NP (Nonapeptide-1)
- HKP-217
- Melanostatine-5
- melanostatine