2,4,5-トリメトキシベンズアルデヒド 化学特性,用途語,生産方法
外観
白色～うすい黄褐色、結晶～結晶性粉末
使用上の注意
窒素封入。
説明
2,4,5-Trimethoxybenzaldehyde (2,4,5-TMBA) is a natural cyclooxygenase-2 (COX-2) activity inhibitor that is present in carrot seeds (Daucus carota L.) and can be synthesised using Indonesia Sweet Flag (Acorus calamus) as a raw material. 2,4,5-TMBA may serve as a synthetic intermediate component for various pharmaceuticals. In addition, 2,4,5-TMBA is also considered a candidate drug for oral non-steroidal anti-inflammatory drugs (NSAIDs)
[1].
[1] LERRICK R I. Synthesis of Nonsteroidal Anti-Inflammatory Drug (NSAID) 2,4,5-Trimethoxybenzaldehyde from Indonesian Calamus oil and Its In Silico Pharmacokinetic Study[J]. Canadian Journal of Chemistry, 2022, 20 1. DOI:
10.1139/cjc-2022-0121.
化学的特性
white to light beige fine crystalline powder
使用
2,4,5-Trimethoxybenzaldehyde is used in the synthesis of stilbene and hydrostibene derivatives as potential anticancer agents, inhibiting tubulin. Also used in the synthesis of HIV-RT inhibitors.
一般的な説明
Beige powder.
空気と水の反応
Insoluble in water.
反応プロフィール
2,4,5-Trimethoxybenzaldehyde is light sensitive. .
健康ハザード
SYMPTOMS: Symptoms of exposure to related compounds are skin and gastrointestinal tract irritation, sensitization, blistering, nausea, vomiting, diarrhea, urinary tract irritation, initial excitement, convulsions and central nervous system depression.
火災危険
Flash point data for 2,4,5-Trimethoxybenzaldehyde are not available, but 2,4,5-Trimethoxybenzaldehyde is probably combustible.
2,4,5-トリメトキシベンズアルデヒド 上流と下流の製品情報
原材料
準備製品