モダフィニル
モダフィニル 物理性質
- 融点 :
- 164-166°C
- 沸点 :
- 559.1±50.0 °C(Predicted)
- 比重(密度) :
- 1.283±0.06 g/cm3(Predicted)
- 闪点 :
- 2℃
- 貯蔵温度 :
- Store at +4°C
- 溶解性:
- DMSO: 18 mg/mL、可溶
- 外見 :
- 白い固体
- 酸解離定数(Pka):
- 14.88±0.40(Predicted)
- 色:
- 白い
- BCS Class:
- 4
- 主な用途:
- 法医学と毒物学
- InChI:
- 1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)
- InChIKey:
- YFGHCGITMMYXAQ-UHFFFAOYSA-N
- SMILES:
- NC(=O)CS(=O)C(c1ccccc1)c2ccccc2
- CAS データベース:
- 68693-11-8(CAS DataBase Reference)
モダフィニル 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
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モダフィニル 化学特性,用途語,生産方法
用途
第1種向精神薬睡眠覚醒障害治療
効能
中枢神経刺激薬
商品名
モディオダール (アルフレッサファーマ); モディオダール (アルフレッサファーマ)
説明
Modafinil, a centrally active α
1-adrenergic agonist, was marketed in France as a
psychostimulant for the treatment of narcolepsy and idiopathic hypersomnia
including Gelineau's syndrome. In monkeys, modafinil was found to induce potent
behavioral stimulation and awakening without stereotyped behavior. In narcoleptic
patients, modafinil reduces the daily number of sleep attacks significantly and
markedly improves performance. The mechanism of action for its locomotor effects
was reported to be due to the stimulation of the central α
1-adrenergic system,
opposite to amphetamine and methylphenidate, which act mainly by dopaminergic
mechanisms. Modafinil has been reported to exhibit minimal peripheral side effects
at therapeutic doses and appears to have low abuse potential. The use of modafinil
in the treatment of cerebral infarction and ischemia has been claimed.
化学的特性
Crystalline Solid
使用
Modafinil is an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.
一般的な説明
Modafinil (Provigil) has overall wakefulness-promotingproperties similar to those of central sympathomimetics. It isconsidered an atypical α1-norepinephrine (NE) receptorstimulant and is used to treat daytime sleepiness in narcolepsypatients. Adverse reactions at therapeutic doses arereportedly not severe and may include nervousness, anxiety,and insomnia. Modafinil is used by oral administration.
生物活性
Psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease. Promotes vigilence and wakefulness without the central and peripheral side effects associated with conventional dopaminergic psychostimulants. Mechanism of action is not fully understood, possibly via modulation of catecholamine/GABAergic neurotransmission.
モダフィニル 上流と下流の製品情報
原材料
準備製品
モダフィニル 生産企業
Global( 0)Suppliers
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68693-11-8(モダフィニル)キーワード:
- 68693-11-8
- MODAFINIL
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- MODAFINIL-DEA SCHEDULE IV
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- CRL-40476
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- ModafinilQ: What is
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Modafinil Q: What is the storage condition of
Modafinil Q: What are the applications of
Modafinil
- Modafinil CIV (1445404)
- (ベンズヒドリルスルフィニル)アセトアミド
- モディオダール
- 2-[(ジフェニルメチル)スルフィニル]アセトアミド
- モダフィニル
- 2-(ジフェニルメチルスルフィニル)アセトアミド
- モダフィニル 溶液
- モダフィニル (JAN)
- 2-(ベンズヒドリルスルフィニル)アセトアミド
- 2-ジフェニルメタンスルフィニルアセトアミド
- ベンズヒドリルスルフィニルアセトアミド
- ジフェニルメチルスルフィニルアセトアミド