3-モルホリノシドノンイミン-3-イウム·塩酸塩
3-モルホリノシドノンイミン-3-イウム·塩酸塩 物理性質
- 融点 :
- 186 °C
- 比重(密度) :
- 1.303 at 20℃
- 貯蔵温度 :
- -20°C
- 溶解性:
- DMSO (最大 35mg/ml) または水 (最大 65mg/ml) に可溶。
- 外見 :
- 白い固体
- 色:
- 白い
- 水溶解度 :
- 溶ける
- 安定性：:
- 使用時は現地でご用意ください。
- InChI:
- 1S/C6H10N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5,7H,1-4H2;1H
- InChIKey:
- NCGICGYLBXGBGN-UHFFFAOYSA-N
- SMILES:
- Cl[H].[NH-]c1c[n+](no1)N2CCOCC2
- LogP:
- -6.28 at 25℃
- CAS データベース:
- 16142-27-1(CAS DataBase Reference)
3-モルホリノシドノンイミン-3-イウム·塩酸塩 価格
もっと(11)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CAY82220 |
SIN-1 (chloride) |
16142-27-1 |
10mg |
￥9000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CAY82220 |
SIN-1 (chloride) |
16142-27-1 |
50mg |
￥36700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
M5793 |
3-モルホリノシドノンイミン 塩酸塩 (consistent with structure, NMR)
3-Morpholinosydnonimine hydrochloride (consistent with structure, NMR) |
16142-27-1 |
25mg |
￥35500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
M5793 |
3-モルホリノシドノンイミン 塩酸塩 (consistent with structure, NMR)
3-Morpholinosydnonimine hydrochloride (consistent with structure, NMR) |
16142-27-1 |
100mg |
￥145000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC0756 |
SIN-1 chloride |
16142-27-1 |
50mg |
￥56000 |
2024-03-01 |
購入 |
3-モルホリノシドノンイミン-3-イウム·塩酸塩 化学特性,用途語,生産方法
溶解性
水に可溶。
説明
As the active metabolite of molsidomine, SIN-
1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.
化学的特性
White Crystalline Solid
使用
3-Morpholinosydnonimine hydrochloride is a metabolite of the vasodilator Molsidomine (M488002) and is considered to be a peroxynitrite releasing compound. Molsidomine Impurity A.
適応症
Linsidomine (SIN-1) is an active metabolite of the
antianginal drug molsidomine. Its mechanism of action
upon the corpus cavernosum involves the release of nitric
oxide. Injected intracavernosally it can produce penile
erections, but its clinical usefulness has not been
fully established.
生物活性
This compound (the active product of the prodrug SIN-10, molsidomine) acts as a vasodilator and inhibitor of platelet aggregation; longer acting than nitroprusside or nitroglycerin. Decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion.
3-モルホリノシドノンイミン-3-イウム·塩酸塩 上流と下流の製品情報
原材料
準備製品
3-モルホリノシドノンイミン-3-イウム·塩酸塩 生産企業
Global( 150)Suppliers
3-モルホリノシドノンイミン-3-イウム·塩酸塩 スペクトルデータ(1HNMR)
16142-27-1(3-モルホリノシドノンイミン-3-イウム·塩酸塩)キーワード:
- 16142-27-1
- 3-(4-MORPHOLINYL)-SYDNONE IMINE HYDROCHLORIDE
- 3-MORPHOLINOSYDNOIMINE HCL
- 3-MORPHOLINOSYDNOIMINE HYDROCHLORIDE
- 3-MORPHOLINOSYDNONIMINE CHLORIDE
- 3-MORPHOLINOSYDNONIMINE HCL
- 3-MORPHOLINOSYDNONIMINE HYDROCHLORIDE
- 3-MORPHOLINOSYDNONIMIN HYDROCHLORIDE
- 5-AMINO-3-MORPHOLINYL-1,2,3-OXADIAZOLIUM CHLORIDE
- 5-AMINO-3-MORPHOLIN-4-YL-[1,2,3]OXADIAZOL-3-IUM, CHLORIDE
- 5-AMINO-3-(4-MORPHOLINYL)-1,2,3-OXADIAZOLIUM CHLORIDE
- SIN-1, Hydrochloride - CAS 16142-27-1 - Calbiochem
- (3-Morpholino-1,2,3-oxadiazol-3-ium-5-yl)amide hydrochloride
- 3-(4-Morpholinyl)sydnone IMine Monohydrochloride
- 3-Morpholinosydnone IMine Monohydrochloride
- LinsidoMine Chlorhydrate
- MolsidoMine IMpurity A
- Molsidomine Impurity A (3-(Morpholin-4-yl)-Sydnonimine)
- Linsidomine (chloride)
- Molsidomine EP impurity A
- 3-(4-morpholinyl)-2H-oxadiazol-2-ium-5-amine chloride
- LINSIDOMINE HCL
- LINSIDOMINE HYDROCHLORIDE
- SIN-I HYDROCHLORIDE
- SIN-1
- SIN-1 HCL
- SIN-1 HYDROCHLORIDE
- 3-morpholinosydnoneiminehydrochloride
- 3-morpholino-sydnoneiminmonohydrochloride
- 3-(4-Morpholinyl)sydnonimine,hydrochloride
- 3-(4-MORPHOLINYL)SYDNONIMINE HYDROCHLORIDE (SIN-1)
- 3-モルホリノシドノンイミン-3-イウム·塩酸塩
- 3-モルホリノシドノニミン·塩酸塩
- リンシドミン塩酸塩
- 3-(4-モルホリニル)シドノンイミン塩酸塩
- 3-モルホリノシドノンイミン 塩酸塩