ピロクトンオラミン

ピロクトンオラミン 化学構造式
68890-66-4
CAS番号.
68890-66-4
化学名:
ピロクトンオラミン
别名:
オクトピロックス;2-アミノエタノール/1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドン,(1:1);ピロクトン/2-アミノエタノール,(1:1);1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドン·2-アミノエタノール;1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリジノン/2-アミノエタノール,(1:1);ピロクトンオラミン;1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドンエタノールアミン;1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)ピリジン-2(1H)-オンと2-アミノエタノールの化合物;1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドン・2-アミノエタノール
英語名:
Piroctone olamine
英語别名:
OCTOPIROX;OCTO;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one;PIROCTONE OLEAMINE;LGB-PO;Hydropyridone;octopiroxolamine;HIC-cosmetics-RM;PIROCTONE OLAMINE;Piorctone Olamine
CBNumber:
CB6433396
化学式:
C16H30N2O3
分子量:
298.43
MOL File:
68890-66-4.mol
MSDS File:
SDS

ピロクトンオラミン 物理性質

融点 :
134.0 to 138.0 °C
沸点 :
135-235℃[at 101 325 Pa]
比重(密度) :
1.1[at 20℃]
蒸気圧:
0-0Pa at 20-25℃
貯蔵温度 :
Inert atmosphere,2-8°C
溶解性:
クロロホルム(微量、超音波処理)、メタノール(微量)
酸解離定数(Pka):
5.9-7.4[at 20 ℃]
外見 :
Solid
色:
ホワイトからオフホワイト
水溶解度 :
400-50000mg/L at 20-25℃
Merck :
14,7502
主な用途:
農業
環境
化粧品成分の機能:
防腐剤
抗脂漏性
InChI:
InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
InChIKey:
BTSZTGGZJQFALU-UHFFFAOYSA-N
SMILES:
C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C
LogP:
1.05-3.86 at 20-25℃
CAS データベース:
68890-66-4(CAS DataBase Reference)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
WGK Germany  2
RTECS 番号 UU7786150
HSコード  2933399090
ストレージクラス 11 - Combustible Solids
Hazard Classifications Aquatic Chronic 3
Eye Dam. 1
Skin Irrit. 2
絵表示(GHS) Corrosion (GHS05)
注意喚起語 危険
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 P264, P280, P302+P352, P321,P332+P313, P362
H318 重篤な眼の損傷 眼に対する重篤な損傷性/眼刺激 性 1 危険 P280, P305+P351+P338, P310
H412 長期的影響により水生生物に有害 水生環境有害性、慢性毒性 3 P273, P501
注意書き
P273 環境への放出を避けること。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P302+P352 皮膚に付着した場合:多量の水と石鹸で洗うこと。

ピロクトンオラミン 価格 もっと(6)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01USP1544406 ピロクトンオラミン
Piroctone Olamine
68890-66-4 200mg ¥95900 2024-03-01 購入
東京化成工業 P2178 ピロクトンオラミン >97.0%(HPLC)(T)
Piroctone Olamine >97.0%(HPLC)(T)
68890-66-4 1g ¥9600 2024-03-01 購入
東京化成工業 P2178 ピロクトンオラミン >97.0%(HPLC)(T)
Piroctone Olamine >97.0%(HPLC)(T)
68890-66-4 5g ¥32100 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) 32333-52
Piroctoneolamine
68890-66-4 5g ¥4400 2024-07-01 購入
富士フイルム和光純薬株式会社(wako) 32333-32
Piroctoneolamine
68890-66-4 25g ¥7000 2024-07-01 購入

ピロクトンオラミン 化学特性,用途語,生産方法

外観

白色~ほとんど白色粉末~結晶

定義

本品は、次の化学式で表されるアミン塩である。

無機性値/有機性値

749/290

化粧品の成分用途

殺菌剤

効能

脂漏性湿疹薬

使用

Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma.

定義

ChEBI: An organoammonium salt that is the ethanolamine salt of piroctone.

brand name

Octopirox (Hoechst AG, Germany).

利点

Piroctone Olamine is a popular ingredient in hair care products that treat dandruff and other scalp conditions. Controls dandruff: Piroctone Olamine is effective at controlling the growth of Malassezia, a yeast that can contribute to dandruff and other scalp issues. By controlling the growth of this yeast, Piroctone Olamine can help to reduce or eliminate dandruff. Soothes the scalp: Piroctone Olamine has moisturizing properties that can help to soothe and hydrate the scalp. This can help prevent dryness, flakiness, and itching, common symptoms of dandruff and other scalp conditions. Safe for coloured hair: Piroctone Olamine is safe for use on coloured hair and will not cause fading or strip colour. Prevents fungal growth: Piroctone Olamine not only controls the growth of Malassezia, but it also prevents the growth of other fungi that can cause scalp problems. Long-lasting effect: Piroctone Olamine has been shown to have a longer-lasting effect than some other dandruff-fighting ingredients, meaning you may be able to go longer between washes. Gentle on the scalp: Piroctone Olamine is gentle on the scalp, making it suitable for sensitive skin.

作用機序

Piroctone olamine, also known as Octopirox, is an antifungal and antibacterial agent commonly used in cosmetic and personal care products, such as shampoos, conditioners, and lotions. It works by inhibiting the growth of various microorganisms, including yeasts and fungi, by disrupting their cell membranes and interfering with their metabolism. Specifically, piroctone olamine targets the enzymes responsible for synthesizing the cell membrane of microorganisms, inhibiting their growth and causing their eventual death. It also has anti-inflammatory properties that help to reduce redness and itching on the scalp and skin.

臨床応用

Piroctone olamine has both antifungal and antioxidant properties. It has been reported to be as effective as other antidandruff products at concentrations of 0.5–1% and is considered less toxic than zinc pyrithione when accidentally swallowed. Piroctone olamine products can be used by all patients and at any age. Like zinc pyrithione, they should be used daily. Because of their reduced toxicity, they may be preferred if used around small children.

副作用

It should be kept in mind that shampoos with Piroctone Olamine should not be used more than twice a week, unlike other daily-use shampoos that don't have this ingredient. One of the biggest side effects of Piroctone Olamine is that it can cause irritation and itchiness on the head.

ピロクトンオラミン 上流と下流の製品情報

原材料

準備製品


ピロクトンオラミン 生産企業

Global( 608)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Spec-Chem Industry Inc. 025-84523390 13505162978
sc@specchemind.com China 123 58
East Star Biotech (Suzhou) Co., Ltd. 0512-62620298 17520198886
18636423@qq.com China 29 58
Beri Pharma Co., Ltd. 0756-8699456 13427714006
sales@zhberi.com China 199 58
BLiT (Hefei)Chemical Co.,Ltd 62622640 13225513950
leo@blitchem.com China 288 58
Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 15367835770
sales@huatengsci.com China 5869 58
Shandong flying Chemical Co., Ltd 18954855616
920481088@qq.com China 33 58
Jinan Wanduoxin Chemical Co., Ltd. 0531-88770993 13905318421
wonderfulchem@163.com China 268 58
ZHENYOU LIAO (WUHAN) BIOTECHNOLOGY CO., LTD. 18062454418
info@zenunite-bio.com China 75 58
YANGZHOU NO.3 PHARMACEUTICAL CO.,LTD 18944498819
yzsy-api@qq.com China 19 58
INTATRADE GmbH +49 3493/605464
sales@intatrade.de Germany 3563 66

ピロクトンオラミン  スペクトルデータ(1HNMR)


68890-66-4(ピロクトンオラミン)キーワード:


  • 68890-66-4
  • 2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1)
  • 4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon
  • octopiroxolamine
  • 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1)
  • Hydroxyl pyrazole ketones
  • 1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine
  • 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)
  • -one compound with 2-aminoethanol (1:1)
  • Ethanolamine salt (1:1)
  • Piroctone olamine Solution, 100ppm
  • PIROCTONE OLAMINE 98.0+%
  • 1-hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt
  • PIROCTONE OLAMINE
  • Piroctone olamine (OCTO)
  • PIROCTONE OLEAMINE
  • 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
  • Piorctone Olamine
  • 1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)2(1H)-PYRIDONE.
  • 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-on, Verbindung mit 2-Aminoethanol (1:1)
  • 1-hydroxy-4-Methyl-6-(2,4,4-triMethylpentyl)pyridin-2(1H)-one-2-aMinoethanol (1:1)
  • Pyridine-aMino ethanol
  • 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
  • 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone·2-aminoethanol
  • 2-Aminoethanol/1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone,(1:1)
  • Piroctone Olamine (200 mg)
  • 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt
  • PiroCLone olaMine
  • LGB-PO
  • 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone
  • Piroctone olamine/octopirox
  • オクトピロックス
  • 2-アミノエタノール/1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドン,(1:1)
  • ピロクトン/2-アミノエタノール,(1:1)
  • 1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドン·2-アミノエタノール
  • 1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリジノン/2-アミノエタノール,(1:1)
  • ピロクトンオラミン
  • 1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドンエタノールアミン
  • 1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)ピリジン-2(1H)-オンと2-アミノエタノールの化合物
  • 1-ヒドロキシ-4-メチル-6-(2,4,4-トリメチルペンチル)-2(1H)-ピリドン・2-アミノエタノール
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