2-フルオロアニリン 化学特性,用途語,生産方法
外観
わずかにうすい黄色～暗褐色, 澄明の液体
溶解性
水に難溶。アルコール, アセトンに易溶。エタノール及びアセトンに極めて溶けやすく、水にほとんど溶けない。
用途
ジルコニウムの沈殿剤、有機合成原料、フタル酸塩製造原料
使用上の注意
不活性ガス封入
化学的特性
2-Fluoroaniline is a clear colorless to brown liquid, toxic, insoluble in water, soluble in ethanol and ether, its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of fire and high heat. Reacts with oxidants. Decomposed by high heat to release toxic gases.
使用
2-Fluoroaniline (cas# 348-54-9) is a useful reagent for the synthesis of insecticides.
定義
ChEBI: 2-fluoroaniline is a derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate It is a primary arylamine and a fluoroaniline.
一般的な説明
Clear liquid with a mild sweet odor. Sinks in and mixes slowly with water.
空気と水の反応
Water soluble.
反応プロフィール
2-Fluoroaniline is a base. Neutralizes acids to form salts plus water in an exothermic reaction. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
健康ハザード
Inhalation or ingestion causes bluish tint to fingernails, lips and ears indicative of cyanosis; headache, drowsiness, and nausea, followed by unconsciousness. Liquid can be absorbed through skin and cause similar symptoms. Contact with eyes causes irritation.
火災危険
Special Hazards of Combustion Products: Irritating and toxic hydrogen fluoride and oxides of nitrogen may form in fires.
代謝経路
2-Fluoro and 3-fluoroanilines are preferentially
hydroxylated at the para-position, and 4-fluoroaniline is
both p- and o-hydroxylated to a significant extent by
rat liver microsomes and is not accompanied with an
NIH shift to give 4-hydroxyl-3-fluoroaniline.
2-フルオロアニリン 上流と下流の製品情報
原材料
準備製品