キシメラガトラン

キシメラガトラン 価格 もっと(8)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TRCX745000	キシメラガトラン Ximelagatran	192939-46-1	0.5mg	￥22500	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCX745000	キシメラガトラン Ximelagatran	192939-46-1	1mg	￥34900	2023-06-01	購入
Sigma-Aldrich Japan	SML1768	≥98% (HPLC) Ximelagatran ≥98% (HPLC)	192939-46-1	5mg	￥33900	2024-03-01	購入
Sigma-Aldrich Japan	SML1768	≥98% (HPLC) Ximelagatran ≥98% (HPLC)	192939-46-1	25mg	￥137000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCX745000	キシメラガトラン Ximelagatran	192939-46-1	2.5mg	￥68400	2024-03-01	購入

キシメラガトラン 化学特性,用途語,生産方法

効能

抗凝固薬, トロンビン阻害薬

説明

Ximelagatran is an ester prodrug of melagatran, a potent, direct, and reversible thrombin inhibitor (K_i = 1.2 nM). While melagatran has poor oral bioavailability, ximelagatran displays good bioavailability resulting, in part, from rapid absorption at the gastrointestinal tract, as well as rapid onset of action. Ximelagatran is converted to melagatran by reduction and hydrolysis at the liver and other tissues. It is used as an anticoagulant in a variety of situations, including thromboembolic disorders, stroke prevention in atrial fibrillation, and therapy in vein thrombosis.

化学的特性

Off-White Amorphous Solid

定義

ChEBI: A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted to the corresponding amidoxime. A prodrug for melagatran, ximela atran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage.

キシメラガトラン 上流と下流の製品情報

原材料

準備製品

キシメラガトラン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501	product@acmec-e.com	China	33301	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
xinguokeji	13120711461	363372932@qq.com	China	477	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4854	55
ShangHai Biochempartner Co.,Ltd	177-54423994 17754423994	2853530910@QQ.com	China	8000	62
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9696	58

192939-46-1(キシメラガトラン)キーワード:

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• 192939-46-1
• N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine Ethyl Ester
• EXANTA
• Glycine, N-[(1R)-1-cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyaMino)iMinoMethyl]phenyl]Methyl]aMino]carbonyl]-1-azetidinyl]-2-oxoethyl]-, ethyl ester
• Exanta (XiMelagatran)
• Ethyl 2-[[(1R)-1-Cyclohexyl-2-[(2S)-2-[[4-(N'-Hydroxycarbamimidoyl)Phenyl]Methylcarbamoyl]Azetidin-1-Yl]-2-Oxoethyl]Amino]Acetate Ximelagatran
• Ethyl 2-[[(1R)-1-Cyclohexyl-2-[(2S)-2-[[4-(N'-Hydroxycarbamimidoyl)Phenyl]Methylcarbamoyl]Azetidin-1-Yl]-2-Oxoethyl]Amino]Acetate Ethyl 2-[[(1R)-1-Cyclohexyl-2-[(2S)-2-[[4-(N'-Hydroxycarbamimidoyl)Phenyl]Methylcarbamoyl]Azetidin-1-Yl]-2-Oxo-Ethyl
• XIMELEGATRAN
• EXANTA/XIMELEGATRAN
• H 376/95
• CS-1834
• Exanta (TN)
• EXANTA; EXARTA; H 376-95; EXANTA (TN); H 376/95; H 37695; XIMELAGATRAN [USAN:INN]; XIMELAGATRAN (JAN/USAN/INN)
• Exarta
• Ximelagatran (JAN/USAN/INN)
• Ximelagatran [USAN:INN]
• Ximelagatran (H 376/95)
• Inhibitor,inhibit,Ximelagatran,Thrombin
• Ethyl ((R)-1-cyclohexyl-2-((S)-2-((4-(N-hydroxycarbamimidoyl)benzyl)carbamoyl)azetidin-1-yl)-2-oxoethyl)glycinate
• ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-({[4-(N-hydroxycarbamimidoyl)phenyl]methyl}carbamoyl)azetidin-1-yl]-2-oxoethyl]amino}acetate
• Ximelagatran, 10 mM in DMSO
• キシメラガトラン
• キシメラガトラン (JAN)