N-ニトロソ-N-エチル尿素 化学特性,用途語,生産方法
用途
合成中間体、試薬、変異原性試験用薬
化学的特性
Orange Paste
使用
A precursor of Diazoethane
定義
ChEBI: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
一般的な説明
Yellow-pink crystals or off-white powder. Sensitive to light.
空気と水の反応
Water soluble. Sensitive to moisture--stability in aqueous solutions depends on pH.
反応プロフィール
N-NITROSO-N-ETHYLUREA is highly reactive. Sensitive to moisture and light. Its stability in aqueous solutions is pH-dependent. Incompatible with water and nucleophilic reagents. Alkaline hydrolysis produces a highly explosive gas. .
危険性
Tumorigen, carcinogen, neoplastigen; teratogen; poison; toxic.
健康ハザード
ACUTE/CHRONIC HAZARDS: N-NITROSO-N-ETHYLUREA is extremely unstable at high pH. It will decompose to extremely unstable decomposition products if acidic conditions are not maintained. When heated to decomposition it emits toxic fumes of nitrogen oxides. Decomposition products may be explosive.
火災危険
Flash point data for N-NITROSO-N-ETHYLUREA are not available; however, N-NITROSO-N-ETHYLUREA is probably combustible.
安全性プロファイル
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by ingestion, subcutaneous,
intraperitoneal, and intravenous routes.
Human mutation data reported. When
heated to decomposition it emits toxic
fumes of NOx. See also N-NITROSO
COMPOUNDS.
職業ばく露
Used as a chemical intermediate for
dyes and pharmaceuticals; a polymerization inhibitor during
the manufacture of vinyl monomers such as styrene; a
precursor of diazoethane; accelerator for rubber vulcanization.
発がん性
N-Nitroso-N-ethylurea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
輸送方法
Toxic solids, organic, n.o.s., Hazard Class: 6.1;
Labels: 6.1-Poisonous materials, Technical Name Required.
UN3077 Environmentally hazardous substances, solid,
n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous
material, Technical Name Required.
不和合性
N-nitroso-N-ethylurea is highly reactive.
Sensitive to moisture and light. Its stability in aqueous
solutions is pH-dependent. Incompatible with water and
nucleophilic reagents. Alkaline hydrolysis produces a
highly explosive gas. This compound is extremely
unstable at high pH. It will decompose to extremely
unstable decomposition products if acidic conditions are
not maintained. Nitrated organics range from slight to
strong oxidizing agents. If mixed with reducing agents,
including hydrides, sulfides and nitrides, they may begin a
vigorous reaction. Reaction with
廃棄物の処理
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations
governing storage, transportation, treatment, and waste
disposal.
N-ニトロソ-N-エチル尿素 上流と下流の製品情報
原材料
準備製品