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ChemicalBook >> CAS DataBase List >> 3-(2-chloropyriMidin-4-yl)-1-Methylindole

3-(2-chloropyriMidin-4-yl)-1-Methylindole

3-(2-chloropyriMidin-4-yl)-1-Methylindole price.
  • $9 - $890
  • Product name: 3-(2-chloropyriMidin-4-yl)-1-Methylindole
  • CAS: 1032452-86-0
  • MF: C13H10ClN3
  • MW: 243.69
  • EINECS:806-155-8
  • MDL Number:MFCD26397861
  • Synonyms:3-(2-chloropyriMidin-4-yl)-1-Methylindole;EOS-61220;elagolix intermediate 11;3-(2-Chloro-4-pyrimidyl)-1-methylindole;3-(2-Chloro-4-pyrimidinyl)-1-methyl-1H-indole ，98%;1H-Indole, 3-(2-chloro-4-pyrimidinyl)-1-methyl-;-(2-Chloropyrimidin-4-yl)-1-Methylindole;3- (2-chloro-4-pyridine) -1-methyl indole
Price21 Properties Safety Information Description
21 prices
Selected condition：
Brand
  • aablocks
  • AccelPharmtech
  • Ambeed
  • American Custom Chemicals Corporation
  • Chemenu
  • Crysdot
  • Synthonix
  • TRC
Package
  • 5MG
  • 100mg
  • 1g
  • 5g
  • 10G
  • 25g
  • 100g
  • 500g
  • 1KG
  • Manufactureraablocks
  • Product numberAA003967
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97%
  • Packaging1g
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003967
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97%
  • Packaging5g
  • Price$11
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003967
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging25g
  • Price$30
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003967
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging100g
  • Price$92
  • Updated2026-05-28
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberXP1529
  • Product description3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00%
  • Packaging10G
  • Price$120
  • Updated2026-05-21
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberXP1529
  • Product description3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00%
  • Packaging1KG
  • Price$890
  • Updated2026-05-21
  • Buy
  • ManufacturerAmbeed
  • Product numberA104126
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging100g
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104126
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging1g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104126
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging10g
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104126
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging25g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104126
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging5g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0620635
  • Product description3-(2-CHLOROPYRIMIDIN-4-YL)-1-METHYLINDOLE 95.00%
  • Packaging5MG
  • Price$505.3
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105137
  • Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+
  • Packaging500g
  • Price$468
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105137
  • Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+
  • Packaging100g
  • Price$139
  • Updated2026-05-26
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11362631
  • Product description3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98%
  • Packaging100g
  • Price$174
  • Updated2026-05-27
  • Buy
  • ManufacturerSynthonix
  • Product numberC16140
  • Product description3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 97.0%
  • Packaging100g
  • Price$150
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003967 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97% 1g $10 2026-05-28 Buy
aablocks AA003967 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole ≥97% 5g $11 2026-05-28 Buy
aablocks AA003967 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 25g $30 2026-05-28 Buy
aablocks AA003967 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 100g $92 2026-05-28 Buy
AccelPharmtech XP1529 3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00% 10G $120 2026-05-21 Buy
AccelPharmtech XP1529 3-(2-chloropyriMidin-4-yl)-1-Methyl-1H-indole 99.00% 1KG $890 2026-05-21 Buy
Ambeed A104126 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 100g $128 2021-12-16 Buy
Ambeed A104126 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 1g $9 2021-12-16 Buy
Ambeed A104126 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 10g $32 2021-12-16 Buy
Ambeed A104126 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 25g $39 2021-12-16 Buy
Ambeed A104126 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 5g $19 2021-12-16 Buy
American Custom Chemicals Corporation HCH0620635 3-(2-CHLOROPYRIMIDIN-4-YL)-1-METHYLINDOLE 95.00% 5MG $505.3 2021-12-16 Buy
Chemenu CM105137 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+ 500g $468 2021-12-16 Buy
Chemenu CM105137 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 95%+ 100g $139 2026-05-26 Buy
Crysdot CD11362631 3-(2-Chloropyrimidin-4-yl)-1-methyl-1H-indole 98% 100g $174 2026-05-27 Buy
Synthonix C16140 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole 97.0% 100g $150 2026-05-06 Buy
Next Last

Properties

Melting point :201 °C (decomp)(Solvent: Acetonitrile; Water)
Boiling point :486.3±28.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
pka :-0.89±0.31(Predicted)
Appearance :Off-white to light yellow Solid
InChI :InChI=1S/C13H10ClN3/c1-17-8-10(9-4-2-3-5-12(9)17)11-6-7-15-13(14)16-11/h2-8H,1H3
InChIKey :IIBWXYHPBMUNJP-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C(C2C=CN=C(Cl)N=2)=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

3-(2-Chloropyrimidin-4-yl)-1-methylindole is a key intermediate in the synthesis of Osimertinib Mesylate. Osimertinib Mesylate (Trade Name: Tagrisso) is a targeted anticancer drug developed by AstraZeneca. It received marketing approval from the U.S. Food and Drug Administration (FDA) on November 13, 2015, and from the European Medicines Agency (EMA) on February 2, 2016, respectively. Later, it was also approved for marketing by the Pharmaceuticals and Medical Devices Agency (PMDA) of Japan on March 28, 2016. This medication is indicated for the treatment of non-small cell lung cancer (NSCLC) positive for the EGFR-T790M mutation.

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Suppliers and manufacturers

Jinan XuanDe Chemical Co., Ltd. Hangzhou Chemtrue Bio-Tech Co.,Ltd. AstaTech(Chengdu) Biopharmaceutical Corp. Shandong Xuanshuo Pharmaceutical Technology Co. LTD TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD. Jia Xing Isenchem Co.,Ltd Nanjing Chemlin Chemical Co., Ltd Nanjing Chemipioneer Pharma& Tech Co., LTD Shanghai Kuanghao Chemistry Technology Co., Ltd. Spectrum Chemical Manufacturing Corp.