10Z-HYMENIALDISINE
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- $160 - $948
- Product name: 10Z-HYMENIALDISINE
- CAS: 82005-12-7
- MF: C11H10BrN5O2
- MW: 324.13
- EINECS:
- MDL Number:MFCD04037007
- Synonyms:(4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one;(Z)-Hymenialdisine;4-(2-AMINO-4-OXO-2-IMIDAZOLIDIN-5-YLIDENE)-2-BROMO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8-ONE;10Z-HYMENIALDISINE;Hymenialdesine;ANTI-HD antibody produced in mouse;(4Z)-4-(2-amino-4-oxo-1H-imidazol-5-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one;(Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one
23 prices
Selected condition：
Brand
- aablocks
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- Cayman Chemical
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 100μg
- 0.5mg
- 500ug
- 500μg
- 1mg
- 500??g
- Manufactureraablocks
- Product numberAA004YRZ
- Product description10Z-Hymenialdisine >97%
- Packaging1mg
- Price$948
- Updated2026-05-28
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0067-C500
- Product description10Z-Hymenialdisine ≥97%(HPLC)(Containstracesofthe10E-isomer)
- Packaging500μg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0067-C500
- Product description10Z-Hymenialdisine ≥97%(HPLC)(Containstracesofthe10E-isomer)
- Packaging500μg
- Price$240
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberX3835
- Product description10Z-Hymenialdisine
- Packaging1mg
- Price$573
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5126
- Product description10Z-Hymenialdisine
- Packaging1mg
- Price$622
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5126
- Product description10Z-Hymenialdisine
- Packaging500ug
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5126
- Product description10Z-Hymenialdisine
- Packaging1mg
- Price$486
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5126
- Product description10Z-Hymenialdisine
- Packaging500ug
- Price$514
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N6794
- Product description10Z-Hymenialdisine 97.0%
- Packaging500??g
- Price$542
- Updated2026-05-26
- Buy
- ManufacturerCayman Chemical
- Product number14198
- Product description10Z-Hymenialdisine ≥97%
- Packaging1mg
- Price$351
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14198
- Product description10Z-Hymenialdisine ≥97%
- Packaging500μg
- Price$194
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number11077
- Product description10Z-Hymenialdisine
- Packaging1mg
- Price$925
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSAB1411884
- Product descriptionANTI-HD antibody produced in mouse clone 3F9, purified immunoglobulin, buffered aqueous solution
- Packaging100μg
- Price$541
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberSAB1411874
- Product descriptionANTI-HD antibody produced in mouse clone 1A12, purified immunoglobulin, buffered aqueous solution
- Packaging100μg
- Price$541
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberSAB1411856
- Product descriptionANTI-HD antibody produced in mouse clone 1H6, purified immunoglobulin, buffered aqueous solution
- Packaging100μg
- Price$541
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberSAB1411875
- Product descriptionANTI-HD antibody produced in mouse clone 4F11, purified immunoglobulin, buffered aqueous solution
- Packaging100μg
- Price$541
- Updated2025-07-31
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA004YRZ | 10Z-Hymenialdisine >97% | 1mg | $948 | 2026-05-28 | Buy |
| Adipogen Life Sciences | AG-CN2-0067-C500 | 10Z-Hymenialdisine ≥97%(HPLC)(Containstracesofthe10E-isomer) | 500μg | $210 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0067-C500 | 10Z-Hymenialdisine ≥97%(HPLC)(Containstracesofthe10E-isomer) | 500μg | $240 | 2026-05-06 | Buy |
| AK Scientific | X3835 | 10Z-Hymenialdisine | 1mg | $573 | 2021-12-16 | Buy |
| ApexBio Technology | B5126 | 10Z-Hymenialdisine | 1mg | $622 | 2026-05-06 | Buy |
| ApexBio Technology | B5126 | 10Z-Hymenialdisine | 500ug | $270 | 2021-12-16 | Buy |
| ApexBio Technology | B5126 | 10Z-Hymenialdisine | 1mg | $486 | 2021-12-16 | Buy |
| ApexBio Technology | B5126 | 10Z-Hymenialdisine | 500ug | $514 | 2026-05-06 | Buy |
| Arctom | HY-N6794 | 10Z-Hymenialdisine 97.0% | 500??g | $542 | 2026-05-26 | Buy |
| Cayman Chemical | 14198 | 10Z-Hymenialdisine ≥97% | 1mg | $351 | 2021-12-16 | Buy |
| Cayman Chemical | 14198 | 10Z-Hymenialdisine ≥97% | 500μg | $194 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 11077 | 10Z-Hymenialdisine | 1mg | $925 | 2021-12-16 | Buy |
| Sigma-Aldrich | SAB1411884 | ANTI-HD antibody produced in mouse clone 3F9, purified immunoglobulin, buffered aqueous solution | 100μg | $541 | 2025-07-31 | Buy |
| Sigma-Aldrich | SAB1411874 | ANTI-HD antibody produced in mouse clone 1A12, purified immunoglobulin, buffered aqueous solution | 100μg | $541 | 2025-07-31 | Buy |
| Sigma-Aldrich | SAB1411856 | ANTI-HD antibody produced in mouse clone 1H6, purified immunoglobulin, buffered aqueous solution | 100μg | $541 | 2025-07-31 | Buy |
| Sigma-Aldrich | SAB1411875 | ANTI-HD antibody produced in mouse clone 4F11, purified immunoglobulin, buffered aqueous solution | 100μg | $541 | 2025-07-31 | Buy |
Properties
Density :2.20±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble to 10 mM in DMSO
pka :9.86±0.20(Predicted)
form :Yellow oil.
color :White to light yellow
biological source :mouse
storage temp. :-20°C
solubility :Soluble to 10 mM in DMSO
pka :9.86±0.20(Predicted)
form :Yellow oil.
color :White to light yellow
biological source :mouse
Safety Information
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Description
10Z-Hymenialdisine is a natural marine sponge alkaloid with numerous cellular actions. Most notably, it blocks signaling through the Raf-1/MEK-1/MAPK pathway by potently inhibiting MEK-1 (IC50 = 9 nM). Hymenialdisine also inhibits numerous kinases in vitro, most notably GSK3β, CDK1/cyclin B, CDK5/p25, CK1, and CDK2/cyclin E (IC50s = 10, 22, 28, 35, and 40 nM, respectively), as well as, less potently, ERK1/2 and several isoforms of PKC. Early studies demonstrated that it suppresses inflammatory gene expression by blocking signaling through NF-κB at micromolar concentrations. At similar concentrations, hymenialdisine also blocks bacterial quorum sensing.Related product price
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