N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide
![N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide price.](/CAS/20181012/GIF/1105698-15-4.gif)
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- $9 - $1600
- Product name: N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide
- CAS: 1105698-15-4
- MF: C26H22N2O2
- MW: 394.47
- EINECS:
- MDL Number:MFCD12912446
- Synonyms:N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide;Salermide;N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide;SIRT1/2 Inhibitor VIII, Salermide ;CS-2458;SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4 - Calbiochem;N-[3-[[(2-HYDROXY-1-NAPHTHALENYL)METHYLENE]AMINO]PHENYL]-A-METHYL-BENZENEACETAMIDE;Benzeneacetamide, N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methyl-
48 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mg
- 50
- 25mg
- 50mg
- 100mg
- 250MG
- 1g
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA008SPP
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99%
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SPP
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99%
- Packaging5mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SPP
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99%
- Packaging10mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SPP
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99%
- Packaging25mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SPP
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99%
- Packaging50mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SPP
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide ≥98%(HPLC)
- Packaging100mg
- Price$43
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD265015
- Product descriptionSalermide 98%
- Packaging100MG
- Price$355
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD265015
- Product descriptionSalermide 98%
- Packaging250MG
- Price$710
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2029AH
- Product descriptionSalermide
- Packaging100mg
- Price$779
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA557147
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
- Packaging25mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA557147
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
- Packaging50mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA557147
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA557147
- Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
- Packaging10mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7594
- Product descriptionSalermide
- Packaging10mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7594
- Product descriptionSalermide
- Packaging50mg
- Price$280
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-101073
- Product descriptionSalermide 98.0%
- Packaging50mg
- Price$228
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008SPP | N-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99% | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA008SPP | N-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99% | 5mg | $12 | 2026-05-28 | Buy |
| aablocks | AA008SPP | N-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99% | 10mg | $14 | 2026-05-28 | Buy |
| aablocks | AA008SPP | N-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99% | 25mg | $17 | 2026-05-28 | Buy |
| aablocks | AA008SPP | N-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide 99% | 50mg | $23 | 2026-05-28 | Buy |
| aablocks | AA008SPP | N-(3-(((2-Hydroxynaphthalen-1-Yl)Methylene)Amino)Phenyl)-2-Phenylpropanamide ≥98%(HPLC) | 100mg | $43 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD265015 | Salermide 98% | 100MG | $355 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD265015 | Salermide 98% | 250MG | $710 | 2026-05-27 | Buy |
| AK Scientific | 2029AH | Salermide | 100mg | $779 | 2021-12-16 | Buy |
| Ambeed | A557147 | N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% | 25mg | $88 | 2021-12-16 | Buy |
| Ambeed | A557147 | N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% | 50mg | $115 | 2021-12-16 | Buy |
| Ambeed | A557147 | N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% | 5mg | $51 | 2021-12-16 | Buy |
| Ambeed | A557147 | N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% | 10mg | $67 | 2021-12-16 | Buy |
| ApexBio Technology | B7594 | Salermide | 10mg | $70 | 2026-05-06 | Buy |
| ApexBio Technology | B7594 | Salermide | 50mg | $280 | 2026-05-06 | Buy |
| Arctom | HY-101073 | Salermide 98.0% | 50mg | $228 | 2026-05-26 | Buy |
Properties
Melting point :>250 °C
Boiling point :666.7±50.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.90±0.50(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C26H22N2O2/c1-18(19-8-3-2-4-9-19)26(30)28-22-12-7-11-21(16-22)27-17-24-23-13-6-5-10-20(23)14-15-25(24)29/h2-18,29H,1H3,(H,28,30)/b27-17+
InChIKey :HQSSEGBEYORUBY-WPWMEQJKSA-N
SMILES :CC(C(=O)Nc1cccc(c1)\N=C\c2c(O)ccc3ccccc23)c4ccccc4
Boiling point :666.7±50.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.90±0.50(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C26H22N2O2/c1-18(19-8-3-2-4-9-19)26(30)28-22-12-7-11-21(16-22)27-17-24-23-13-6-5-10-20(23)14-15-25(24)29/h2-18,29H,1H3,(H,28,30)/b27-17+
InChIKey :HQSSEGBEYORUBY-WPWMEQJKSA-N
SMILES :CC(C(=O)Nc1cccc(c1)\N=C\c2c(O)ccc3ccccc23)c4ccccc4
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 μM) by reactivating proapototic genes that are repressed by SIRT1.Related product price
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