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ChemicalBook >> CAS DataBase List >> 1-Boc-3-(cyanomethylene)azetidine

1-Boc-3-(cyanomethylene)azetidine

1-Boc-3-(cyanomethylene)azetidine price.
  • $4 - $4059
  • Product name: 1-Boc-3-(cyanomethylene)azetidine
  • CAS: 1153949-11-1
  • MF: C10H14N2O2
  • MW: 194.23
  • EINECS:606-276-4
  • MDL Number:MFCD12761241
  • Synonyms:1-Boc-3-(cyanomethylene)azetidine;3-Cyanomethylene-azetidine-1-carboxylic acid tert-butyl ester;tert-butyl 3-(cyanoMethylidene)azetidine-1-carboxylate;3-(Cyanomethylene)-1-azetidinecarboxylic acid tert-butyl ester;1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine;P-Hydroxy phenyl butanone (Raspberry ketone);tert-Butyl 3-(cyanomethylene);1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine
Price36 Properties Safety Information Description
36 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Acrotein
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Chemenu
  • Chem-Impex
  • Crysdot
  • Matrix Scientific
  • Synthonix
  • TCI Chemical
  • TRC
Package
  • 5MG
  • 200MG
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  • 5g
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  • 2.5kg
  • Manufactureraablocks
  • Product numberAA000FTX
  • Product descriptiontert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98%
  • Packaging1g
  • Price$8
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000FTX
  • Product descriptiontert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98%
  • Packaging5g
  • Price$10
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000FTX
  • Product descriptiontert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98%
  • Packaging10g
  • Price$16
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000FTX
  • Product descriptiontert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98%
  • Packaging25g
  • Price$19
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000FTX
  • Product descriptiontert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98%
  • Packaging100g
  • Price$72
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberC-3409
  • Product description1-Boc-3-(cyanomethylene)azetidine 97%
  • Packaging25G
  • Price$18
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberC-3409
  • Product description1-Boc-3-(cyanomethylene)azetidine 97%
  • Packaging1G
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberC-3409
  • Product description1-Boc-3-(cyanomethylene)azetidine 97%
  • Packaging5G
  • Price$4
  • Updated2026-05-27
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  • ManufacturerAcrotein
  • Product numberAT-0788
  • Product description1-Boc-3-(cyanomethylene)-azetidine 97%
  • Packaging5g
  • Price$29.15
  • Updated2026-05-25
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  • ManufacturerAcrotein
  • Product numberAT-0788
  • Product description1-Boc-3-(cyanomethylene)-azetidine 97%
  • Packaging1g
  • Price$21.45
  • Updated2021-12-16
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  • ManufacturerAcrotein
  • Product numberAT-0788
  • Product description1-Boc-3-(cyanomethylene)-azetidine 97%
  • Packaging25g
  • Price$100.74
  • Updated2026-05-25
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  • ManufacturerAcrotein
  • Product numberAT-0788
  • Product description1-Boc-3-(cyanomethylene)-azetidine 97%
  • Packaging100g
  • Price$268.13
  • Updated2026-05-25
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  • ManufacturerAK Scientific
  • Product numberJ56933
  • Product description1-Boc-3-(cyanomethylene)azetidine
  • Packaging1g
  • Price$14
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number1153949111
  • Product descriptiontert-Butyl3-(cyanomethylene)azetidine-1-carboxylate
  • Packaging100g
  • Price$400
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0290724
  • Product descriptionTERT-BUTYL-3-(CYANOMETHYLENE)AZETIDINE-1-CARBOXYLATE 95.00%
  • Packaging5MG
  • Price$497.62
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR930876
  • Product descriptiontert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 97%
  • Packaging500g
  • Price$985
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000FTX tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98% 1g $8 2026-05-25 Buy
aablocks AA000FTX tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98% 5g $10 2026-05-25 Buy
aablocks AA000FTX tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98% 10g $16 2026-05-25 Buy
aablocks AA000FTX tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98% 25g $19 2026-05-25 Buy
aablocks AA000FTX tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 98% 100g $72 2026-05-25 Buy
ACHEMBLOCK C-3409 1-Boc-3-(cyanomethylene)azetidine 97% 25G $18 2026-05-27 Buy
ACHEMBLOCK C-3409 1-Boc-3-(cyanomethylene)azetidine 97% 1G $30 2021-12-16 Buy
ACHEMBLOCK C-3409 1-Boc-3-(cyanomethylene)azetidine 97% 5G $4 2026-05-27 Buy
Acrotein AT-0788 1-Boc-3-(cyanomethylene)-azetidine 97% 5g $29.15 2026-05-25 Buy
Acrotein AT-0788 1-Boc-3-(cyanomethylene)-azetidine 97% 1g $21.45 2021-12-16 Buy
Acrotein AT-0788 1-Boc-3-(cyanomethylene)-azetidine 97% 25g $100.74 2026-05-25 Buy
Acrotein AT-0788 1-Boc-3-(cyanomethylene)-azetidine 97% 100g $268.13 2026-05-25 Buy
AK Scientific J56933 1-Boc-3-(cyanomethylene)azetidine 1g $14 2021-12-16 Buy
Alichem 1153949111 tert-Butyl3-(cyanomethylene)azetidine-1-carboxylate 100g $400 2021-12-16 Buy
American Custom Chemicals Corporation CHM0290724 TERT-BUTYL-3-(CYANOMETHYLENE)AZETIDINE-1-CARBOXYLATE 95.00% 5MG $497.62 2021-12-16 Buy
Apolloscientific OR930876 tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate 97% 500g $985 2026-06-04 Buy
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Properties

Boiling point :309.7±35.0 °C(Predicted)
Density :1.215
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
pka :-1.88±0.20(Predicted)
form :powder to crystal
color :White to Orange to Green
InChI :InChI=1S/C10H14N2O2/c1-10(2,3)14-9(13)12-6-8(7-12)4-5-11/h4H,6-7H2,1-3H3
InChIKey :BESFCRTTXQYNBW-UHFFFAOYSA-N
SMILES :N1(C(OC(C)(C)C)=O)C/C(=C\C#N)/C1

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.

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Related product price

Suppliers and manufacturers

Shaanxi Didu New Materials Co. Ltd
1-Boc-3-(cyanomethylene)azetidine
$1.50
1-Boc-3-(cyanomethylene)azetidine CAS:1153949-11-1
Firsky International Trade (Wuhan) Co., Ltd
1-Boc-3-(cyanomethylene)azetidine
$30.00
1-Boc-3-(cyanomethylene)azetidine CAS:1153949-11-1
Hangzhou ICH Biofarm Co., Ltd
Tert-butyl 3-(cyanomethylene)azetidine-1-carboxylate
Tert-butyl 3-(cyanomethylene)azetidine-1-carboxylate CAS:1153949-11-1
Henan Fengda Chemical Co., Ltd
1-Boc-3-(cyanomethylene)azetidine
$500.00
1-Boc-3-(cyanomethylene)azetidine CAS:1153949-11-1
Cangzhou Kangrui Pharma Tech Co. Ltd.,
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate CAS:1153949-11-1
Hefei Lbao Physical & Chemical Science Co.,Ltd
1-Boc-3-(cyanomethylene)azetidine
1-Boc-3-(cyanomethylene)azetidine CAS:1153949-11-1
SHANGHAI SAGACHEM CO., LTD.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED