1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone
![1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone price.](/CAS/GIF/117690-79-6.gif)
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- $10 - $2984
- Product name: 1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone
- CAS: 117690-79-6
- MF: C19H28N4O3
- MW: 360.45
- EINECS:
- MDL Number:MFCD00876422
- Synonyms:LY 255283;1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOLE-5-YL)HEPTYL]OXY]PHENYL]-ETHANONE;5'-Ethyl-2'-hydroxy-4'-[6-methyl-6-(1H-tetrazol-5-yl)heptyloxy]acetophenone;CGS 23356;1-[5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-tetrazol-5-yl)heptoxy]phenyl]ethanone;Ethanone, 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(2H-tetrazol-5-yl)heptyl]oxy]phenyl]-;1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one;parcnchyma,LTB4,Leukotriene Receptor,inhibit,BLT2,LY255283,lung,Inhibitor,LY-255283
52 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 5mg
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA007QR4
- Product description1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98%
- Packaging50mg
- Price$128
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007QR4
- Product description1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98%
- Packaging100mg
- Price$229
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007QR4
- Product description1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98%
- Packaging25mg
- Price$71
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007QR4
- Product description1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98%
- Packaging10mg
- Price$33
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007QR4
- Product description1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98%
- Packaging5mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007QR4
- Product description1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98%
- Packaging1mg
- Price$10
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227356
- Product descriptionLY255283 97.00%
- Packaging100MG
- Price$225
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227356
- Product descriptionLY255283 97.00%
- Packaging50MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1134AH
- Product description1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1h-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone
- Packaging25mg
- Price$388
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging25mg
- Price$315
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging10mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging5mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging50mg
- Price$608
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging100mg
- Price$796
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging250mg
- Price$1193
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA646553
- Product descriptionLy255283 98+%
- Packaging1g
- Price$2984
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007QR4 | 1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98% | 50mg | $128 | 2026-05-28 | Buy |
| aablocks | AA007QR4 | 1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98% | 100mg | $229 | 2026-05-28 | Buy |
| aablocks | AA007QR4 | 1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98% | 25mg | $71 | 2026-05-28 | Buy |
| aablocks | AA007QR4 | 1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98% | 10mg | $33 | 2026-05-28 | Buy |
| aablocks | AA007QR4 | 1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98% | 5mg | $19 | 2026-05-28 | Buy |
| aablocks | AA007QR4 | 1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one ≥98% | 1mg | $10 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227356 | LY255283 97.00% | 100MG | $225 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227356 | LY255283 97.00% | 50MG | $140 | 2026-05-27 | Buy |
| AK Scientific | 1134AH | 1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1h-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone | 25mg | $388 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 25mg | $315 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 10mg | $144 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 5mg | $86 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 50mg | $608 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 100mg | $796 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 250mg | $1193 | 2021-12-16 | Buy |
| Ambeed | A646553 | Ly255283 98+% | 1g | $2984 | 2021-12-16 | Buy |
Properties
Melting point :160-162 °C
Boiling point :573.4±60.0 °C(Predicted)
Density :1.157±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >20mg/mL
pka :5.11±0.10(Predicted)
form :powder
color :off-white to light yellow
InChI :1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12,25H,5-10H2,1-4H3,(H,20,21,22,23)
InChIKey :WCGXJPFHTHQNJL-UHFFFAOYSA-N
SMILES :CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c2nnn[nH]2
Boiling point :573.4±60.0 °C(Predicted)
Density :1.157±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >20mg/mL
pka :5.11±0.10(Predicted)
form :powder
color :off-white to light yellow
InChI :1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12,25H,5-10H2,1-4H3,(H,20,21,22,23)
InChIKey :WCGXJPFHTHQNJL-UHFFFAOYSA-N
SMILES :CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c2nnn[nH]2
Safety Information
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Description
Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4) have been potential drug development targets for several years. The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100 nM. LY255283 exhibits IC50 values of ~950 nM and >10 μM at human recombinant BLT2 and BLT1 receptors, respectively. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM, and inhibits the binding of radiolabeled LTB4 to eosinophil membranes with an IC50 of 260 nM.More related product prices
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