[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
|
- $32 - $3791
- Product name: [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
- CAS: 1360705-96-9
- MF: C22H20Cl2N4O4
- MW: 475.32
- EINECS:
- MDL Number:MFCD22666407
- Synonyms:[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone;ML 210 - CID 49766530;[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone;CID 49766530;ML 210;Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-;ML 210 >=98% (HPLC);(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone
65 prices
Selected condition:
Brand
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10
- 2mg
- 500mg
- 10mM(1mLinDMSO)
- 1mL(10mMinDMSO)
- 5mg
- 10mg
- 25MG
- 50mg
- 100MG
- 250mg
- 1g
- ManufacturerACHEMBLOCK
- Product numberV155036
- Product descriptionML 210 98%
- Packaging25MG
- Price$105
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV155036
- Product descriptionML 210 98%
- Packaging100MG
- Price$350
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3040DH
- Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
- Packaging50mg
- Price$498
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3040DH
- Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
- Packaging10mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging5mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging100mg
- Price$473
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging250mg
- Price$977
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging1g
- Price$2171
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberBA3403
- Product descriptionML-210
- Packaging50mg
- Price$432
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3403
- Product descriptionML-210
- Packaging100mg
- Price$604
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3403
- Product descriptionML-210
- Packaging5mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3403
- Product descriptionML-210
- Packaging1mL(10mMinDMSO)
- Price$84
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3403
- Product descriptionML-210
- Packaging10mg
- Price$144
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3403
- Product descriptionML-210
- Packaging25mg
- Price$270
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-100003
- Product descriptionML-210 99.93%
- Packaging25mg
- Price$304
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100003
- Product descriptionML-210 99.93%
- Packaging10mg
- Price$168
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | V155036 | ML 210 98% | 25MG | $105 | 2026-05-27 | Buy |
| ACHEMBLOCK | V155036 | ML 210 98% | 100MG | $350 | 2026-05-27 | Buy |
| AK Scientific | 3040DH | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone | 50mg | $498 | 2021-12-16 | Buy |
| AK Scientific | 3040DH | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone | 10mg | $178 | 2021-12-16 | Buy |
| Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 5mg | $69 | 2021-12-16 | Buy |
| Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 100mg | $473 | 2021-12-16 | Buy |
| Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 250mg | $977 | 2021-12-16 | Buy |
| Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 1g | $2171 | 2021-12-16 | Buy |
| ApexBio Technology | BA3403 | ML-210 | 50mg | $432 | 2026-05-06 | Buy |
| ApexBio Technology | BA3403 | ML-210 | 100mg | $604 | 2026-05-06 | Buy |
| ApexBio Technology | BA3403 | ML-210 | 5mg | $81 | 2026-05-06 | Buy |
| ApexBio Technology | BA3403 | ML-210 | 1mL(10mMinDMSO) | $84 | 2026-05-06 | Buy |
| ApexBio Technology | BA3403 | ML-210 | 10mg | $144 | 2026-05-06 | Buy |
| ApexBio Technology | BA3403 | ML-210 | 25mg | $270 | 2026-05-06 | Buy |
| Arctom | HY-100003 | ML-210 99.93% | 25mg | $304 | 2026-05-26 | Buy |
| Arctom | HY-100003 | ML-210 99.93% | 10mg | $168 | 2026-05-26 | Buy |
Properties
Boiling point :644.7±55.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C22H20Cl2N4O4/c1-14-20(28(30)31)19(25-32-14)22(29)27-12-10-26(11-13-27)21(15-2-6-17(23)7-3-15)16-4-8-18(24)9-5-16/h2-9,21H,10-13H2,1H3
InChIKey :VIBHJPDPEVVDTB-UHFFFAOYSA-N
SMILES :Cc1onc(C(=O)N2CCN(CC2)C(c3ccc(Cl)cc3)c4ccc(Cl)cc4)c1[N+]([O-])=O
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C22H20Cl2N4O4/c1-14-20(28(30)31)19(25-32-14)22(29)27-12-10-26(11-13-27)21(15-2-6-17(23)7-3-15)16-4-8-18(24)9-5-16/h2-9,21H,10-13H2,1H3
InChIKey :VIBHJPDPEVVDTB-UHFFFAOYSA-N
SMILES :Cc1onc(C(=O)N2CCN(CC2)C(c3ccc(Cl)cc3)c4ccc(Cl)cc4)c1[N+]([O-])=O
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
ML210 (CAS 1360705-96-9) is selectively synthetic lethal to HRAS expressing cells compared to isogenic non-HRAS cells (IC50= 7.1 nM for BJeLR (expressing HRASg12v) cells vs IC50= 272 nM for BJeH-LT (non-HRAS expressing) cells.1ML210 is able to inhibit glutathione peroxidase 4 (GPX4), an important selenoenzyme that protects cells from ferroptosis caused by iron catalyzed formation of free radicals from lipid peroxides.2,3Treatment of several treatment-resistant cancer cell lines exhibiting a high mesenchymal state with ML210 resulted in selective induction of ferroptosis.3Related product price
- Paraquat dichloride
$21-897.44 - Methyl butyrate
$10-22601 - ML216
$32-2250




