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ChemicalBook >> CAS DataBase List >> [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone price.
  • $32 - $3791
  • Product name: [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
  • CAS: 1360705-96-9
  • MF: C22H20Cl2N4O4
  • MW: 475.32
  • EINECS:
  • MDL Number:MFCD22666407
  • Synonyms:[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone;ML 210 - CID 49766530;[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone;CID 49766530;ML 210;Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-;ML 210 >=98% (HPLC);(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone
65 prices
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Brand
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10
  • 2mg
  • 500mg
  • 10mM(1mLinDMSO)
  • 1mL(10mMinDMSO)
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100MG
  • 250mg
  • 1g
  • ManufacturerACHEMBLOCK
  • Product numberV155036
  • Product descriptionML 210 98%
  • Packaging25MG
  • Price$105
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberV155036
  • Product descriptionML 210 98%
  • Packaging100MG
  • Price$350
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3040DH
  • Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
  • Packaging50mg
  • Price$498
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3040DH
  • Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
  • Packaging10mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging5mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging100mg
  • Price$473
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging250mg
  • Price$977
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA824339
  • Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
  • Packaging1g
  • Price$2171
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3403
  • Product descriptionML-210
  • Packaging50mg
  • Price$432
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3403
  • Product descriptionML-210
  • Packaging100mg
  • Price$604
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3403
  • Product descriptionML-210
  • Packaging5mg
  • Price$81
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3403
  • Product descriptionML-210
  • Packaging1mL(10mMinDMSO)
  • Price$84
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3403
  • Product descriptionML-210
  • Packaging10mg
  • Price$144
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3403
  • Product descriptionML-210
  • Packaging25mg
  • Price$270
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-100003
  • Product descriptionML-210 99.93%
  • Packaging25mg
  • Price$304
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100003
  • Product descriptionML-210 99.93%
  • Packaging10mg
  • Price$168
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK V155036 ML 210 98% 25MG $105 2026-05-27 Buy
ACHEMBLOCK V155036 ML 210 98% 100MG $350 2026-05-27 Buy
AK Scientific 3040DH [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone 50mg $498 2021-12-16 Buy
AK Scientific 3040DH [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone 10mg $178 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 5mg $69 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 100mg $473 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 250mg $977 2021-12-16 Buy
Ambeed A824339 (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% 1g $2171 2021-12-16 Buy
ApexBio Technology BA3403 ML-210 50mg $432 2026-05-06 Buy
ApexBio Technology BA3403 ML-210 100mg $604 2026-05-06 Buy
ApexBio Technology BA3403 ML-210 5mg $81 2026-05-06 Buy
ApexBio Technology BA3403 ML-210 1mL(10mMinDMSO) $84 2026-05-06 Buy
ApexBio Technology BA3403 ML-210 10mg $144 2026-05-06 Buy
ApexBio Technology BA3403 ML-210 25mg $270 2026-05-06 Buy
Arctom HY-100003 ML-210 99.93% 25mg $304 2026-05-26 Buy
Arctom HY-100003 ML-210 99.93% 10mg $168 2026-05-26 Buy

Properties

Boiling point :644.7±55.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C22H20Cl2N4O4/c1-14-20(28(30)31)19(25-32-14)22(29)27-12-10-26(11-13-27)21(15-2-6-17(23)7-3-15)16-4-8-18(24)9-5-16/h2-9,21H,10-13H2,1H3
InChIKey :VIBHJPDPEVVDTB-UHFFFAOYSA-N
SMILES :Cc1onc(C(=O)N2CCN(CC2)C(c3ccc(Cl)cc3)c4ccc(Cl)cc4)c1[N+]([O-])=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML210 (CAS 1360705-96-9) is selectively synthetic lethal to HRAS expressing cells compared to isogenic non-HRAS cells (IC50= 7.1 nM for BJeLR (expressing HRASg12v) cells vs IC50= 272 nM for BJeH-LT (non-HRAS expressing) cells.1ML210 is able to inhibit glutathione peroxidase 4 (GPX4), an important selenoenzyme that protects cells from ferroptosis caused by iron catalyzed formation of free radicals from lipid peroxides.2,3Treatment of several treatment-resistant cancer cell lines exhibiting a high mesenchymal state with ML210 resulted in selective induction of ferroptosis.3

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