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ChemicalBook >> CAS DataBase List >> Nalpha-methylhistamine dihydrochloride

Nalpha-methylhistamine dihydrochloride

Nalpha-methylhistamine dihydrochloride price.
  • $131 - $3301
  • Product name: Nalpha-methylhistamine dihydrochloride
  • CAS: 16503-22-3
  • MF: C6H11N3.2HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD00134838
  • Synonyms:n-Methylhistamine dihydrochloride;NAMH dihydrochloride;[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride;Nα-Methylhistamine dihydrochloride;Nα-Methylhistamine;2-(1H-Imidazol-4-yl)-N-methylethanamine dihydrochloride;Nα Methylhistamine dihydrochloride,NαMethylhistamine dihydrochloride;Nα-Methylhistamine dihydrochloride
Price28 Properties Safety Information Description
28 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2.5g
  • 5g
  • 10g
  • Manufactureraablocks
  • Product numberAA001V5C
  • Product description[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97%
  • Packaging5mg
  • Price$240
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001V5C
  • Product description[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97%
  • Packaging10mg
  • Price$360
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001V5C
  • Product description[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97%
  • Packaging25mg
  • Price$640
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001V5C
  • Product description[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97%
  • Packaging50mg
  • Price$1022
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number6570BB
  • Product descriptionNalpha-Methylhistaminedihydrochloride
  • Packaging2.5g
  • Price$1502
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6570BB
  • Product descriptionNalpha-Methylhistaminedihydrochloride
  • Packaging5g
  • Price$2160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6570BB
  • Product descriptionNalpha-Methylhistaminedihydrochloride
  • Packaging100mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0003720
  • Product descriptionN-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$384.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6357
  • Product descriptionNα-Methylhistamine dihydrochloride
  • Packaging10mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6357
  • Product descriptionNα-Methylhistamine dihydrochloride
  • Packaging25mg
  • Price$1657
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6357
  • Product descriptionNα-Methylhistamine dihydrochloride
  • Packaging50mg
  • Price$959
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberRAA50322
  • Product descriptionN±-Methylhistamine dihydrochloride
  • Packaging1g
  • Price$1239
  • Updated2026-06-05
  • Buy
  • ManufacturerBiosynth
  • Product numberRAA50322
  • Product descriptionN±-Methylhistamine dihydrochloride
  • Packaging100mg
  • Price$389
  • Updated2026-06-05
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020684
  • Product descriptionN-Methylhistamine dihydrochloride ≥98%
  • Packaging500mg
  • Price$531
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020684
  • Product descriptionN-Methylhistamine dihydrochloride ≥98%
  • Packaging250mg
  • Price$284
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0020684
  • Product descriptionN-Methylhistamine dihydrochloride ≥98%
  • Packaging50mg
  • Price$144
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001V5C [2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97% 5mg $240 2026-05-28 Buy
aablocks AA001V5C [2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97% 10mg $360 2026-05-28 Buy
aablocks AA001V5C [2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97% 25mg $640 2026-05-28 Buy
aablocks AA001V5C [2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride ≥97% 50mg $1022 2026-05-28 Buy
AK Scientific 6570BB Nalpha-Methylhistaminedihydrochloride 2.5g $1502 2021-12-16 Buy
AK Scientific 6570BB Nalpha-Methylhistaminedihydrochloride 5g $2160 2021-12-16 Buy
AK Scientific 6570BB Nalpha-Methylhistaminedihydrochloride 100mg $322 2021-12-16 Buy
American Custom Chemicals Corporation INB0003720 N-ALPHA-METHYLHISTAMINE DIHYDROCHLORIDE 95.00% 100MG $384.3 2021-12-16 Buy
ApexBio Technology B6357 Nα-Methylhistamine dihydrochloride 10mg $228 2021-12-16 Buy
ApexBio Technology B6357 Nα-Methylhistamine dihydrochloride 25mg $1657 2026-05-06 Buy
ApexBio Technology B6357 Nα-Methylhistamine dihydrochloride 50mg $959 2021-12-16 Buy
Biosynth RAA50322 N±-Methylhistamine dihydrochloride 1g $1239 2026-06-05 Buy
Biosynth RAA50322 N±-Methylhistamine dihydrochloride 100mg $389 2026-06-05 Buy
ChemScene CS-0020684 N-Methylhistamine dihydrochloride ≥98% 500mg $531 2026-06-04 Buy
ChemScene CS-0020684 N-Methylhistamine dihydrochloride ≥98% 250mg $284 2026-06-04 Buy
ChemScene CS-0020684 N-Methylhistamine dihydrochloride ≥98% 50mg $144 2026-06-04 Buy
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Properties

Melting point :173-176°C
storage temp. :2-8°C
solubility :H2O: >20mg/mL
form :solid
color :white
Water Solubility :Soluble to 100 mM in water
Stability :Hygroscopic
InChI :1S/C6H11N3.2ClH/c1-7-3-2-6-4-8-5-9-6;;/h4-5,7H,2-3H2,1H3,(H,8,9);2*1H
InChIKey :AYUQICXJAMPXPF-UHFFFAOYSA-N
SMILES :Cl[H].Cl[H].CNCCc1c[nH]cn1

Safety Information

Symbol(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Production of N-alpha-methyl-histamine, which is a histamine 3 receptor (H3R) agonist, is promoted in Helicobacter pylori infected human gastric mucosa. NAMH acts directly on H2Rs in animals to stimulate acid secretion and to be a H2R agonist. NAMH dose dependently stimulated cAMP productions in CHO-H2R cells. This production was inhibited by famotidine but not by thioperamide. Control CHO cells were unresponsive to either histamine or NAMH. In addition, the effect of NAMH, in terms of cAMP production in CHO-H2R cells, was more potent than that of histamine-that is, with a lower EC50 concentration and higher maximal cAMP production. Both NAMH and histamine, but not R-alpha-methyl-histamine, effectively inhibited [(3)H] tiotidine binding to CHO-H2R cells. These results confirm that NAMH, which is produced in the gastric mucosa by H pylori, is a potent H2R agonist as well as a H3R agonist.

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