N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide)
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- $9 - $1800
- Product name: N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide)
- CAS: 17328-16-4
- MF: C16H14Cl2N2O4S
- MW: 401.27
- EINECS:
- MDL Number:MFCD00028183
- Synonyms:4',4'''-Sulfonylbis(α-chloroacetanilide);Bis[4-(chloroacetylamino)phenyl] sulfone;N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide);N,N'-[Sulfonylbis(4,1-phenylene)]bis(2-chloroacetamide);TC-E 5003 (NSC-30176);1-phenylene)bis(2-chloroacetamide);N'-(Sulfonyldi-4;N,N'-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide)
55 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Synthonix
- Tocris
- TRC
- Usbiological
Package
- 50
- 003
- 1mg
- 5mg
- 10mg
- 001
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1G
- 002
- 5G
- 10g
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 97%
- Packaging5mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 97%
- Packaging10mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 97%
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 97%
- Packaging25mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 97%
- Packaging50mg
- Price$47
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 97%
- Packaging100mg
- Price$70
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00B5VI
- Product descriptionTc-e 5003 ≥95%
- Packaging250mg
- Price$120
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127600
- Product descriptionTC-E 5003 98%
- Packaging1G
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127600
- Product descriptionTC-E 5003 98%
- Packaging5G
- Price$525
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number5881CA
- Product descriptionSulfone,bis((4-chloroacetylamino)phenyl)
- Packaging5g
- Price$802
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging250mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging100mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging50mg
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging25mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging1mg
- Price$13
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00B5VI | Tc-e 5003 97% | 5mg | $15 | 2026-05-28 | Buy |
| aablocks | AA00B5VI | Tc-e 5003 97% | 10mg | $22 | 2026-05-28 | Buy |
| aablocks | AA00B5VI | Tc-e 5003 97% | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA00B5VI | Tc-e 5003 97% | 25mg | $30 | 2026-05-28 | Buy |
| aablocks | AA00B5VI | Tc-e 5003 97% | 50mg | $47 | 2026-05-28 | Buy |
| aablocks | AA00B5VI | Tc-e 5003 97% | 100mg | $70 | 2026-05-28 | Buy |
| aablocks | AA00B5VI | Tc-e 5003 ≥95% | 250mg | $120 | 2026-05-28 | Buy |
| ACHEMBLOCK | U127600 | TC-E 5003 98% | 1G | $160 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127600 | TC-E 5003 98% | 5G | $525 | 2026-05-27 | Buy |
| AK Scientific | 5881CA | Sulfone,bis((4-chloroacetylamino)phenyl) | 5g | $802 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 250mg | $272 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 100mg | $160 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 50mg | $106 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 25mg | $71 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 10mg | $42 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 1mg | $13 | 2021-12-16 | Buy |
Properties
Melting point :191-192 °C
Boiling point :704.2±60.0 °C(Predicted)
Density :1.504±0.06 g/cm3(Predicted)
storage temp. :-20°C (des.)
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :11.56±0.70(Predicted)
form :solid
color :Brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :704.2±60.0 °C(Predicted)
Density :1.504±0.06 g/cm3(Predicted)
storage temp. :-20°C (des.)
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :11.56±0.70(Predicted)
form :solid
color :Brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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Description
TC-E 5003 is an inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50 = 1.5 μM for human PRMT1 in a methylation assay). It is selective for PRMT1 over PRMT4/CARM1 and SET7/9 methyltransferases, with less than 5% inhibition at a concentration of 50 μM for SET7/9. TC-E 5003 inhibits growth of MCF-7a breast cancer and LNCaP prostate cancer cells (GI50s = 1.97 and 4.49 μM, respectively) and decreases androgen-dependent gene transcription in vitro. TC-E 5003 (80 mg/kg) also has antimalarial properties and eradicates P. berghei in mice.Related product price
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Suppliers and manufacturers
Fuxin Pharmaceutical
Career Henan Chemica Co
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Bide Pharmatech Ltd.
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.




