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ChemicalBook >> CAS DataBase List >> Benzamide, N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-

Benzamide, N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-

Benzamide, N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- price.
  • $82 - $1365
  • Product name: Benzamide, N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-
  • CAS: 174664-65-4
  • MF: C10H10N2O4
  • MW: 222.2
  • EINECS:
  • MDL Number:MFCD03453553
  • Synonyms:Benzamide, N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-;N-Hydroxy-3-[3-(hydroxyaMino)-3-oxo-1-propen-1-yl]benzaMide;CBHAHDAC inhibitor;N-Hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide
29 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA001ZRY
  • Product descriptionBenzamide,N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- ≥98%
  • Packaging5mg
  • Price$91
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001ZRY
  • Product descriptionBenzamide,N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- ≥98%
  • Packaging10mg
  • Price$169
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001ZRY
  • Product descriptionBenzamide,N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- ≥98%
  • Packaging25mg
  • Price$264
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD263472
  • Product descriptionN-hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide 95%
  • Packaging5MG
  • Price$315
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD263472
  • Product descriptionN-hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide 95%
  • Packaging10MG
  • Price$500
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD263472
  • Product descriptionN-hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide 95%
  • Packaging25MG
  • Price$1000
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1665AH
  • Product descriptionCBHA
  • Packaging5mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001854
  • Product descriptionCBHA 95.00%
  • Packaging5MG
  • Price$195.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4327
  • Product descriptionCBHA
  • Packaging25mg
  • Price$273
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4327
  • Product descriptionCBHA
  • Packaging10mg
  • Price$231
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4327
  • Product descriptionCBHA
  • Packaging10mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4327
  • Product descriptionCBHA
  • Packaging5mg
  • Price$122
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4327
  • Product descriptionCBHA
  • Packaging5mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4327
  • Product descriptionCBHA
  • Packaging25mg
  • Price$364
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-W014004
  • Product descriptionm-Carboxycinnamic acid bishydroxamide 98.0%
  • Packaging10mg
  • Price$342
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-W014004
  • Product descriptionm-Carboxycinnamic acid bishydroxamide 98.0%
  • Packaging5mg
  • Price$214
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001ZRY Benzamide,N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- ≥98% 5mg $91 2026-05-28 Buy
aablocks AA001ZRY Benzamide,N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- ≥98% 10mg $169 2026-05-28 Buy
aablocks AA001ZRY Benzamide,N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]- ≥98% 25mg $264 2026-05-28 Buy
ACHEMBLOCK AD263472 N-hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide 95% 5MG $315 2026-05-27 Buy
ACHEMBLOCK AD263472 N-hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide 95% 10MG $500 2026-05-27 Buy
ACHEMBLOCK AD263472 N-hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide 95% 25MG $1000 2026-05-27 Buy
AK Scientific 1665AH CBHA 5mg $189 2021-12-16 Buy
American Custom Chemicals Corporation INB0001854 CBHA 95.00% 5MG $195.8 2021-12-16 Buy
ApexBio Technology C4327 CBHA 25mg $273 2021-12-16 Buy
ApexBio Technology C4327 CBHA 10mg $231 2026-05-06 Buy
ApexBio Technology C4327 CBHA 10mg $173 2021-12-16 Buy
ApexBio Technology C4327 CBHA 5mg $122 2026-05-06 Buy
ApexBio Technology C4327 CBHA 5mg $91 2021-12-16 Buy
ApexBio Technology C4327 CBHA 25mg $364 2026-05-06 Buy
Arctom HY-W014004 m-Carboxycinnamic acid bishydroxamide 98.0% 10mg $342 2026-05-26 Buy
Arctom HY-W014004 m-Carboxycinnamic acid bishydroxamide 98.0% 5mg $214 2026-05-26 Buy

Properties

Density :1.431±0.06 g/cm3(Predicted)
storage temp. :-20C
solubility :≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
pka :8.69±0.10(Predicted)
form :Off-white solid
color :off-white
Sensitive :Light Sensitive
InChI :1S/C10H10N2O4/c13-9(11-15)5-4-7-2-1-3-8(6-7)10(14)12-16/h1-6,15-16H,(H,11,13)(H,12,14)/b5-4+
InChIKey :OYKBQNOPCSXWBL-SNAWJCMRSA-N
SMILES :N(O)C(=O)c1cc(ccc1)\C=C\C(=O)NO

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Histone deacetylase (HDAC) inhibitors hyperacetylate histones and increase transcriptional activity in selected genes. Importantly, HDAC inhibitors induce apoptosis in some cancer cells and show promise in the treatment of certain forms of cancer. CBHA is a potent HDAC inhibitor, exhibiting ID50 values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively. CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 μM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/kg. The efficacy of CBHA for suppressing tumor growth in mice is enhanced by the addition of retinoic acid.

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