Carbonic Anhydrase IX/XII Inhibitor II(U-104)
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- $11 - $2491
- Product name: Carbonic Anhydrase IX/XII Inhibitor II(U-104)
- CAS: 178606-66-1
- MF: C13H12FN3O3S
- MW: 309.32
- EINECS:
- MDL Number:MFCD00159265
- Synonyms:NSC 213841;Carbonic Anhydrase IX/XII Inhibitor II(U-104);MST-104 ;4-[[[(4-Fluorophenyl)amino]carbonyl]amino]benzenesulfonamide;CS-1653;arbonic Anhydrase IX/XII Inhibitor II(U-104);NSC-213841; MST-104;U104;U 104;4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzesulfonamide
71 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10μg
- 10mM*1mLinDMSO
- 100.00mg
- 10
- 50.00mg
- 250.00mg
- 500mg
- 25μL
- 100μL
- 50
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- 5G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00ABMJ
- Product descriptionU-104 98%
- Packaging1mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABMJ
- Product descriptionU-104 98%
- Packaging5mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABMJ
- Product descriptionU-104 98%
- Packaging10mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABMJ
- Product descriptionU-104 98%
- Packaging50mg
- Price$61
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABMJ
- Product descriptionU-104 98%
- Packaging100mg
- Price$94
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABMJ
- Product descriptionU-104 98%
- Packaging250mg
- Price$158
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33724
- Product descriptionU-104 98%
- Packaging250MG
- Price$245
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33724
- Product descriptionU-104 98%
- Packaging1G
- Price$610
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33724
- Product descriptionU-104 98%
- Packaging5G
- Price$1920
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX5935
- Product descriptionU-104
- Packaging25mg
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5935
- Product descriptionU-104
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5935
- Product descriptionU-104
- Packaging5mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112487
- Product descriptionU-104 98+%
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112487
- Product descriptionU-104 98+%
- Packaging10mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112487
- Product descriptionU-104 98+%
- Packaging50mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA112487
- Product descriptionU-104 98+%
- Packaging100mg
- Price$293
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABMJ | U-104 98% | 1mg | $11 | 2026-05-28 | Buy |
| aablocks | AA00ABMJ | U-104 98% | 5mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00ABMJ | U-104 98% | 10mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00ABMJ | U-104 98% | 50mg | $61 | 2026-05-28 | Buy |
| aablocks | AA00ABMJ | U-104 98% | 100mg | $94 | 2026-05-28 | Buy |
| aablocks | AA00ABMJ | U-104 98% | 250mg | $158 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33724 | U-104 98% | 250MG | $245 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33724 | U-104 98% | 1G | $610 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33724 | U-104 98% | 5G | $1920 | 2026-05-27 | Buy |
| AK Scientific | X5935 | U-104 | 25mg | $211 | 2021-12-16 | Buy |
| AK Scientific | X5935 | U-104 | 10mg | $130 | 2021-12-16 | Buy |
| AK Scientific | X5935 | U-104 | 5mg | $116 | 2021-12-16 | Buy |
| Ambeed | A112487 | U-104 98+% | 5mg | $104 | 2021-12-16 | Buy |
| Ambeed | A112487 | U-104 98+% | 10mg | $134 | 2021-12-16 | Buy |
| Ambeed | A112487 | U-104 98+% | 50mg | $226 | 2021-12-16 | Buy |
| Ambeed | A112487 | U-104 98+% | 100mg | $293 | 2021-12-16 | Buy |
Properties
Melting point :242-243℃
Density :1.523±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
form :powder
pka :9.94±0.12(Predicted)
color :white to beige
biological source :rabbit
InChIKey :YJQZNWPYLCNRLP-UHFFFAOYSA-N
SMILES :Fc1ccc(cc1)NC(=O)Nc2ccc(cc2)[S](=O)(=O)N
Density :1.523±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
form :powder
pka :9.94±0.12(Predicted)
color :white to beige
biological source :rabbit
InChIKey :YJQZNWPYLCNRLP-UHFFFAOYSA-N
SMILES :Fc1ccc(cc1)NC(=O)Nc2ccc(cc2)[S](=O)(=O)N
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Carbonic anhydrases are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to form bicarbonate ion plus a proton. Carbonic anhydrases IX (CAIX) and CAXII are hypoxia and HIF-1-inducible proteins located in cellular transmembranes that regulate intra- and extracellular pH under hypoxic conditions and promote tumor cell survival and invasion in hypoxic microenvironments. U-104 is a ureido-sulfonamide inhibitor of transmembrane CAIX (Ki = 45.1 nM) and CAXII (Ki = 4.5 nM). It demonstrates reduced affinity for the cytosolic isoforms, CAI and CAII (Kis = 5.08 and 9.64 μM, respectively). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models.More related product prices
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