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ChemicalBook >> CAS DataBase List >> (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID

(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID

(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID price.
  • $56 - $10648
  • Product name: (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
  • CAS: 197142-36-2
  • MF: C11H17NO4
  • MW: 227.26
  • EINECS:
  • MDL Number:MFCD08691404
  • Synonyms:(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID;(1s,3s,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;(1S,3S,5S)-N2-BOC-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID;N-Boc-L-cis-4,5-methanoproline;-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;(1S,3S,5S)-2-Boc-2-aza-bicyclo[3.1.0]hexane-3-dicarboxylic acid;(3S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;(1S,3S,5S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Price57 Properties Safety Information Description
57 prices
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  • aablocks
  • ACHEMBLOCK
  • Acrotein
  • Activate Scientific
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  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 98%
  • Packaging50mg
  • Price$56
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 98%
  • Packaging100mg
  • Price$67
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging250mg
  • Price$69
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging500mg
  • Price$130
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging1g
  • Price$247
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging5g
  • Price$936
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging10g
  • Price$1574
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002AJE
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging25g
  • Price$3197
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberH-8784
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging5G
  • Price$1235
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberH-8784
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 95%
  • Packaging1G
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8784
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95%
  • Packaging1G
  • Price$325
  • Updated2026-05-27
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  • ManufacturerAcrotein
  • Product numberA-7867
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97%
  • Packaging0.5g
  • Price$330
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberA-7867
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 97%
  • Packaging1g
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberA-7867
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97%
  • Packaging1g
  • Price$495
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberA-7867
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97%
  • Packaging0.25g
  • Price$220
  • Updated2026-05-25
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59843
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee
  • Packaging1g
  • Price$555
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 98% 50mg $56 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 98% 100mg $67 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 250mg $69 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 500mg $130 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 1g $247 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 5g $936 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 10g $1574 2026-05-28 Buy
aablocks AA002AJE (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 25g $3197 2026-05-28 Buy
ACHEMBLOCK H-8784 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 5G $1235 2026-05-27 Buy
ACHEMBLOCK H-8784 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 95% 1G $500 2021-12-16 Buy
ACHEMBLOCK H-8784 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 95% 1G $325 2026-05-27 Buy
Acrotein A-7867 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% 0.5g $330 2026-05-25 Buy
Acrotein A-7867 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 97% 1g $495 2021-12-16 Buy
Acrotein A-7867 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% 1g $495 2026-05-25 Buy
Acrotein A-7867 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% 0.25g $220 2026-05-25 Buy
Activate Scientific AS59843 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee 1g $555 2021-12-16 Buy
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Properties

Boiling point :355.9±25.0 °C(Predicted)
Density :1.276±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :4.03±0.20(Predicted)
Appearance :Light yellow to yellow Solid

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

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