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ChemicalBook >> CAS DataBase List >> 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide

1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide

1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide price.
  • $29 - $3728.1
  • Product name: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide
  • CAS: 202463-68-1
  • MF: C21H19Cl2IN4O2
  • MW: 557.21
  • EINECS:
  • MDL Number:MFCD01861180
  • Synonyms:AM-281 ,99%;AM 281;CS-1127;AM281;AM-281;1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide AM 281;1H-Pyrazole-3-carboxamide,1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-;1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide;1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide
44 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
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Package
  • 10
  • 1mg
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  • 1g
  • Manufactureraablocks
  • Product numberAA00285Y
  • Product description1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE ≥98%
  • Packaging5mg
  • Price$86
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00285Y
  • Product description1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE ≥98%
  • Packaging1mg
  • Price$29
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00285Y
  • Product description1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE ≥98%
  • Packaging10mg
  • Price$158
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00285Y
  • Product description1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE 99%
  • Packaging50mg
  • Price$460
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227309
  • Product descriptionAM281 97.00%
  • Packaging50MG
  • Price$1000
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227309
  • Product descriptionAM281 97.00%
  • Packaging10MG
  • Price$345
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1865BB
  • Product description1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1865BB
  • Product description1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB6603
  • Product descriptionAM 281
  • Packaging50mg
  • Price$505
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6603
  • Product descriptionAM 281
  • Packaging5mg
  • Price$65
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB6603
  • Product descriptionAM 281
  • Packaging10mg
  • Price$125
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-13505
  • Product descriptionAM281 98.60%
  • Packaging1mg
  • Price$99
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-13505
  • Product descriptionAM281 98.60%
  • Packaging5mg
  • Price$209
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-13505
  • Product descriptionAM281 98.60%
  • Packaging25mg
  • Price$665
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-13505
  • Product descriptionAM281 98.60%
  • Packaging10mg
  • Price$333
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-13505
  • Product descriptionAM281 98.60%
  • Packaging50mg
  • Price$1045
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00285Y 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE ≥98% 5mg $86 2026-05-28 Buy
aablocks AA00285Y 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE ≥98% 1mg $29 2026-05-28 Buy
aablocks AA00285Y 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE ≥98% 10mg $158 2026-05-28 Buy
aablocks AA00285Y 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-4-MORPHOLINYL-1H-PYRAZOLE-3-CARBOXAMIDE 99% 50mg $460 2026-05-28 Buy
ACHEMBLOCK Y227309 AM281 97.00% 50MG $1000 2026-05-27 Buy
ACHEMBLOCK Y227309 AM281 97.00% 10MG $345 2026-05-27 Buy
AK Scientific 1865BB 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide 1mg $133 2021-12-16 Buy
AK Scientific 1865BB 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide 10mg $268 2021-12-16 Buy
ApexBio Technology B6603 AM 281 50mg $505 2026-05-06 Buy
ApexBio Technology B6603 AM 281 5mg $65 2026-05-06 Buy
ApexBio Technology B6603 AM 281 10mg $125 2026-05-06 Buy
Arctom HY-13505 AM281 98.60% 1mg $99 2026-05-26 Buy
Arctom HY-13505 AM281 98.60% 5mg $209 2026-05-26 Buy
Arctom HY-13505 AM281 98.60% 25mg $665 2026-05-26 Buy
Arctom HY-13505 AM281 98.60% 10mg $333 2026-05-26 Buy
Arctom HY-13505 AM281 98.60% 50mg $1045 2026-05-26 Buy

Properties

Density :1.70±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >6 mg/mL
form :solid
pka :10.76±0.20(Predicted)
color :white
InChI :1S/C21H19Cl2IN4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-4-15(22)12-17(18)23)20(13)14-2-5-16(24)6-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
InChIKey :AJFFBPZYXRNAIC-UHFFFAOYSA-N
SMILES :Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(I)cc3)C(=O)NN4CCOCC4

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AM 281 is a potent, selective analog of the cannabinoid receptor (CB1) antagonist SR 141716A. Potent CB1 ( CB1 receptor )antagonist/inverse agonist (Ki=14nM). AM 281 increases locomotor activity following systemic administration in vivo. Reported to be an analog of SR141716A.

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