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ChemicalBook >> CAS DataBase List >> N4-(6-Aminopyrimidin-4-yl)-sulfanilamide HCl

N4-(6-Aminopyrimidin-4-yl)-sulfanilamide HCl

$16 - $1737
Product name: N4-(6-Aminopyrimidin-4-yl)-sulfanilamide HCl
CAS: 21886-12-4
MF: C10H12ClN5O2S
MW: 301.75
EINECS:
MDL Number:MFCD00023272
Synonyms:4-[(6-amino-4-pyrimidinyl)amino]-benzenesulfonamide hydrochloride;XBXQRCJKDCEQBS-UHFFFAOYSA-N;PNU 112455A;PNU 112455A HYDROCHLORIDE;4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride;anticooperative,Cyclin dependent kinase,PNU112455A hydrochloride,Alzheimer's,site,disease,competitive,PNU112455A,PNU-112455A hydrochloride,inhibit,CDK,Inhibitor,ATP;4-[(6-amino-4-pyrimidinyl)amino]-benzenesulfonamide, monohydrochloride;PNU112455A hydrochloride, 10 mM in DMSO

Price41 Properties Safety Information Description

41 prices

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Brand

aablocks
ACHEMBLOCK
Ambeed
American Custom Chemicals Corporation
Arctom
Cayman Chemical
Chemenu
ChemScene
CSNpharm
DC Chemicals
Sigma-Aldrich
TRC

Package

10mM*1mLinDMSO(Solution)
1mg
5mg
10mM*1mLinDMSO(Solid+Solvent)
10mg
25mg
50mg
100MG
250MG
1G
5G
10G

Manufactureraablocks
Product numberAA00BCGV
Product descriptionPNU 112455A hydrochloride 97%
Packaging10mg
Price$49
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BCGV
Product descriptionPNU 112455A hydrochloride 97%
Packaging1mg
Price$16
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BCGV
Product descriptionPNU 112455A hydrochloride 97%
Packaging5mg
Price$34
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BCGV
Product descriptionPNU 112455A hydrochloride 97%
Packaging25mg
Price$82
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberX210290
Product description4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride 97%
Packaging100MG
Price$300
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberX210290
Product description4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride 97%
Packaging250MG
Price$530
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberX210290
Product description4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride 97%
Packaging1G
Price$1590
Updated2026-05-27
Buy

ManufacturerAmbeed
Product numberA245488
Product description4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%
Packaging1g
Price$1737
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA245488
Product description4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%
Packaging250mg
Price$709
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA245488
Product description4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%
Packaging100mg
Price$382
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA245488
Product description4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%
Packaging50mg
Price$200
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA245488
Product description4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%
Packaging10mg
Price$112
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA245488
Product description4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%
Packaging5mg
Price$63
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberCHM0162665
Product description4-[(6-AMINOPYRIMIDIN-4-YL)AMINO]BENZENE-1-SULFONAMIDE HYDROCHLORIDE 95.00%
Packaging1G
Price$621.69
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberCHM0162665
Product description4-[(6-AMINOPYRIMIDIN-4-YL)AMINO]BENZENE-1-SULFONAMIDE HYDROCHLORIDE 95.00%
Packaging5G
Price$838.12
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberCHM0162665
Product description4-[(6-AMINOPYRIMIDIN-4-YL)AMINO]BENZENE-1-SULFONAMIDE HYDROCHLORIDE 95.00%
Packaging10G
Price$1183.57
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00BCGV	PNU 112455A hydrochloride 97%	10mg	$49	2026-05-28	Buy
aablocks	AA00BCGV	PNU 112455A hydrochloride 97%	1mg	$16	2026-05-28	Buy
aablocks	AA00BCGV	PNU 112455A hydrochloride 97%	5mg	$34	2026-05-28	Buy
aablocks	AA00BCGV	PNU 112455A hydrochloride 97%	25mg	$82	2026-05-28	Buy
ACHEMBLOCK	X210290	4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride 97%	100MG	$300	2026-05-27	Buy
ACHEMBLOCK	X210290	4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride 97%	250MG	$530	2026-05-27	Buy
ACHEMBLOCK	X210290	4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride 97%	1G	$1590	2026-05-27	Buy
Ambeed	A245488	4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%	1g	$1737	2021-12-16	Buy
Ambeed	A245488	4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%	250mg	$709	2021-12-16	Buy
Ambeed	A245488	4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%	100mg	$382	2021-12-16	Buy
Ambeed	A245488	4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%	50mg	$200	2021-12-16	Buy
Ambeed	A245488	4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%	10mg	$112	2021-12-16	Buy
Ambeed	A245488	4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamidehydrochloride 97%	5mg	$63	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0162665	4-[(6-AMINOPYRIMIDIN-4-YL)AMINO]BENZENE-1-SULFONAMIDE HYDROCHLORIDE 95.00%	1G	$621.69	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0162665	4-[(6-AMINOPYRIMIDIN-4-YL)AMINO]BENZENE-1-SULFONAMIDE HYDROCHLORIDE 95.00%	5G	$838.12	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0162665	4-[(6-AMINOPYRIMIDIN-4-YL)AMINO]BENZENE-1-SULFONAMIDE HYDROCHLORIDE 95.00%	10G	$1183.57	2021-12-16	Buy

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Properties

storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: soluble5mg/mL (clear solution)
form :powder
color :white to beige

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PNU 112455A hydrochloride is a selective and ATP-competitive inhibitor of CDK2/cyclin E (K_i = 2 μM) and CDK5/p35 (p25) (K_i = 2 μM). It binds to the ATP-binding pocket of CDK2 and does not affect the activities of c-met, IGF-1 receptor tyrosine kinase, cAMP-dependent kinase and ERK2 at concentrations as high as 100 μM.

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Suppliers and manufacturers

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Rechem science Co., Ltd. Shanghai Chaolan Chemical Technology Center Wuxi Donghe Pharmaceutical Technology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Shanghai Kaiwei Chemical Technology Co., Ltd. Chunchuang (Wuhan) Technology Co., Ltd

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N4-(6-Aminopyrimidin-4-yl)-sulfanilamide HCl

Properties

Safety Information

Description

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