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ChemicalBook >> CAS DataBase List >> Chloromethyl chloroformate

Chloromethyl chloroformate

Chloromethyl chloroformate price.
  • $90.65 - $818
  • Product name: Chloromethyl chloroformate
  • CAS: 22128-62-7
  • MF: C2H2Cl2O2
  • MW: 128.94
  • EINECS:244-793-3
  • MDL Number:MFCD00077688
  • Synonyms:CHLOROFORMIC ACID CHLOROMETHYL ESTER;CHLOROMETHYL CHLOROFORMATE;CMCF;JMC;CHLOROMETHYL CHLOROFORMATE (JMC)(INTERMEDIATE OF TENOFOVIR DISOPROXIL FUMARATE);Chloromethylchloroformate,97%;chlorocarbonicacidchloromethylester ;Chloromethyl Chloroformate (JMC)
9 prices
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Brand
  • AHH
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
Package
  • 1g
  • 10g
  • 10ml
  • 25g
  • 50mL
  • 50g
  • 100g
  • 500g
  • ManufacturerAHH
  • Product numberMT-05788
  • Product descriptionChloromethyl chloroformate 97%
  • Packaging500g
  • Price$636
  • Updated2026-05-26
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number68651
  • Product descriptionChloroformicAcidChloromethylEster
  • Packaging1g
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number23181
  • Product descriptionChloromethyl chloroformate ≥98.0% (GC)
  • Packaging50mL
  • Price$818
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number23181
  • Product descriptionChloromethyl chloroformate ≥98.0% (GC)
  • Packaging10ml
  • Price$227
  • Updated2026-04-30
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  • ManufacturerTCI Chemical
  • Product numberC1396
  • Product descriptionChloromethyl Chloroformate >95.0%(GC)(T)
  • Packaging25g
  • Price$221
  • Updated2026-04-30
  • Buy
  • ManufacturerTCI Chemical
  • Product numberC1396
  • Product descriptionChloromethyl Chloroformate >95.0%(GC)(T)
  • Packaging100g
  • Price$580
  • Updated2026-04-30
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberL09527
  • Product descriptionChloromethyl chloroformate 97%
  • Packaging10g
  • Price$90.65
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberL09527
  • Product descriptionChloromethyl chloroformate 97%
  • Packaging50g
  • Price$344.65
  • Updated2026-04-24
  • Buy
  • ManufacturerTRC
  • Product numberC366500
  • Product descriptionChloroformicAcidChloromethylEster
  • Packaging50g
  • Price$275
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-05788 Chloromethyl chloroformate 97% 500g $636 2026-05-26 Buy
Medical Isotopes, Inc. 68651 ChloroformicAcidChloromethylEster 1g $620 2021-12-16 Buy
Sigma-Aldrich 23181 Chloromethyl chloroformate ≥98.0% (GC) 50mL $818 2026-04-30 Buy
Sigma-Aldrich 23181 Chloromethyl chloroformate ≥98.0% (GC) 10ml $227 2026-04-30 Buy
TCI Chemical C1396 Chloromethyl Chloroformate >95.0%(GC)(T) 25g $221 2026-04-30 Buy
TCI Chemical C1396 Chloromethyl Chloroformate >95.0%(GC)(T) 100g $580 2026-04-30 Buy
Thermo Scientific Chemicals L09527 Chloromethyl chloroformate 97% 10g $90.65 2026-04-24 Buy
Thermo Scientific Chemicals L09527 Chloromethyl chloroformate 97% 50g $344.65 2026-04-24 Buy
TRC C366500 ChloroformicAcidChloromethylEster 50g $275 2021-12-16 Buy

Properties

Melting point :<-20°C
Boiling point :107-108 °C(lit.)
Density :1.449 g/mL at 20 °C
refractive index :n20/D 1.428
Flash point :95°C
storage temp. :2-8°C
solubility :Chloroform (Soluble), Methanol (Slightly)
form :clear liquid
color :Colorless to Light yellow to Light orange
Water Solubility :Slightly miscible with water.
Sensitive :Moisture Sensitive
BRN :506426
Stability :Extremely Moisture Sensitive, Hygroscopic
InChI :1S/C2H2Cl2O2/c3-1-6-2(4)5/h1H2
InChIKey :JYWJULGYGOLCGW-UHFFFAOYSA-N
SMILES :ClCOC(Cl)=O
CAS DataBase Reference :22128-62-7(CAS DataBase Reference)
EPA Substance Registry System :Carbonochloridic acid, chloromethyl ester (22128-62-7)

Safety Information

Symbol(GHS): Corrosion (GHS05)Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.

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