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ChemicalBook >> CAS DataBase List >> Diethyl cyanomethylphosphonate

Diethyl cyanomethylphosphonate

Diethyl cyanomethylphosphonate price.
  • $6 - $3019.7
  • Product name: Diethyl cyanomethylphosphonate
  • CAS: 2537-48-6
  • MF: C6H12NO3P
  • MW: 177.14
  • EINECS:219-806-0
  • MDL Number:MFCD00001893
  • Synonyms:(Cyanomethyl)diethoxyphosphine oxide;2-(Diethylphosphonyl)acetonitrile;Diethyl cyanomethanephosphonate;Phosphonic acid, (cyanomethyl)-, diethyl ester;Cyanomethylphosphonic acid diethyl ester~Diethyl phosphonoacetonitrile;Diethylcyanomethylphosphonate,98+%;Diethyl (cyanomethyl)phosphonate 98%;LABOTEST-BB LT00233137
Price69 Properties Safety Information Description
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  • ManufacturerAcrotein
  • Product numberAC-7425
  • Product descriptionDiethyl (cyanomethyl)phosphonate 97%
  • Packaging25g
  • Price$24.75
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberAC-7425
  • Product descriptionDiethyl (cyanomethyl)phosphonate 97%
  • Packaging100g
  • Price$64.9
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberAC-7425
  • Product descriptionDiethyl (cyanomethyl)phosphonate 97%
  • Packaging500g
  • Price$176.91
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20469
  • Product descriptionDiethyl cyanomethyl phosphonate >99%(GC)
  • Packaging100g
  • Price$74
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ90229
  • Product descriptionDiethyl cyanomethylphosphonate
  • Packaging500g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberU838
  • Product descriptionDiethyl cyanomethyl phosphonate 98%(GC)
  • Packaging500g
  • Price$199
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20469
  • Product descriptionDiethyl cyanomethyl phosphonate >99%(GC)
  • Packaging500g
  • Price$267
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberU838
  • Product descriptionDiethyl cyanomethyl phosphonate 98%(GC)
  • Packaging1kg
  • Price$334
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberU838
  • Product descriptionDiethyl cyanomethyl phosphonate 98%(GC)
  • Packaging25g
  • Price$23
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberU838
  • Product descriptionDiethyl cyanomethyl phosphonate 98%(GC)
  • Packaging100g
  • Price$55
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20469
  • Product descriptionDiethyl cyanomethyl phosphonate >99%(GC)
  • Packaging25g
  • Price$30
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberU838
  • Product descriptionDiethyl cyanomethyl phosphonate 98%(GC)
  • Packaging5g
  • Price$16
  • Updated2026-06-04
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging100g
  • Price$18
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging10g
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging25g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging1kg
  • Price$118
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein AC-7425 Diethyl (cyanomethyl)phosphonate 97% 25g $24.75 2026-05-25 Buy
Acrotein AC-7425 Diethyl (cyanomethyl)phosphonate 97% 100g $64.9 2026-05-25 Buy
Acrotein AC-7425 Diethyl (cyanomethyl)phosphonate 97% 500g $176.91 2026-05-25 Buy
AK Scientific J20469 Diethyl cyanomethyl phosphonate >99%(GC) 100g $74 2026-06-04 Buy
AK Scientific J90229 Diethyl cyanomethylphosphonate 500g $180 2021-12-16 Buy
AK Scientific U838 Diethyl cyanomethyl phosphonate 98%(GC) 500g $199 2026-06-04 Buy
AK Scientific J20469 Diethyl cyanomethyl phosphonate >99%(GC) 500g $267 2026-06-04 Buy
AK Scientific U838 Diethyl cyanomethyl phosphonate 98%(GC) 1kg $334 2026-06-04 Buy
AK Scientific U838 Diethyl cyanomethyl phosphonate 98%(GC) 25g $23 2026-06-04 Buy
AK Scientific U838 Diethyl cyanomethyl phosphonate 98%(GC) 100g $55 2026-06-04 Buy
AK Scientific J20469 Diethyl cyanomethyl phosphonate >99%(GC) 25g $30 2026-06-04 Buy
AK Scientific U838 Diethyl cyanomethyl phosphonate 98%(GC) 5g $16 2026-06-04 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 100g $18 2021-12-16 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 10g $7 2021-12-16 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 25g $10 2021-12-16 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 1kg $118 2021-12-16 Buy
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Properties

Boiling point :101-102 °C0.4 mm Hg(lit.)
Density :1.095 g/mL at 25 °C(lit.)
refractive index :n20/D 1.434(lit.)
Flash point :>230 °F
storage temp. :Inert atmosphere,2-8°C
solubility :Chloroform (Soluble), Methanol (Slightly)
form :Liquid
color :Clear colorless to light yellow
Specific Gravity :1.1261.095
Water Solubility :Miscible with water, chloroform, terahydrofuran, ethyl acetate and methylene chloride.
BRN :1772981
InChI :InChI=1S/C6H12NO3P/c1-3-9-11(8,6-5-7)10-4-2/h3-4,6H2,1-2H3
InChIKey :KWMBADTWRIGGGG-UHFFFAOYSA-N
SMILES :P(CC#N)(=O)(OCC)OCC
CAS DataBase Reference :2537-48-6(CAS DataBase Reference)
NIST Chemistry Reference :Diethyl cyanomethylphosphonate(2537-48-6)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.

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Weifang Mingran Chemical Co., Ltd. Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. Weifang Siyuan Chemical Co., Ltd. Lianyungang Xuanyuan Chemical Co., Ltd Suzhou Zehou Biotechnology Co. , Ltd. Creasyn Finechem(Tianjin) Co., Ltd. J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. Beijing Donghualituo Techonlogy Development Co.,Ltd. Anqing PhiChem Corporation