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ChemicalBook >> CAS DataBase List >> 6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE

6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE

6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE price.
  • $36 - $879
  • Product name: 6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE
  • CAS: 287204-45-9
  • MF: C21H15Cl2FN4O
  • MW: 429.27
  • EINECS:
  • MDL Number:MFCD10565929
  • Synonyms:6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE;PD 180790;PD 180970;PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, 6-(2,6-DICHLOROPHENYL)-2-[(4-FLUORO-3-METHYLPHENYL)AMINO]-8-METHYL-;6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one;PF-1515965;6-(2,6-dichlorophenyl)-2-(4-fluoro-3-methylanilino)-8-methylpyrido[2,3-d]pyrimidin-7-one;PD-180970,PD180970
24 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • Manufactureraablocks
  • Product numberAA00BHTP
  • Product descriptionPD 180970 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BHTP
  • Product descriptionPD 180970
  • Packaging5mg
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BHTP
  • Product descriptionPD 180970
  • Packaging10mg
  • Price$91
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BHTP
  • Product descriptionPD 180970
  • Packaging25mg
  • Price$138
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BHTP
  • Product descriptionPD 180970
  • Packaging50mg
  • Price$197
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227381
  • Product descriptionPD180970 97.00%
  • Packaging25MG
  • Price$175
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227381
  • Product descriptionPD180970 97.00%
  • Packaging100MG
  • Price$525
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2636BB
  • Product description6-(2,6-Dichlorophenyl)-2-[(4-Fluoro-3-Methylphenyl)amino]-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8606
  • Product descriptionPD 180970
  • Packaging10mg
  • Price$231
  • Updated2026-05-06
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1137
  • Product descriptionPD180970
  • Packaging10mg
  • Price$143
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1137
  • Product descriptionPD180970
  • Packaging50mg
  • Price$506
  • Updated2026-05-19
  • Buy
  • ManufacturerBiosynth
  • Product numberFD102315
  • Product descriptionPD-180970
  • Packaging10mg
  • Price$439.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD102315
  • Product descriptionPD-180970
  • Packaging25mg
  • Price$879
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD102315
  • Product descriptionPD-180970
  • Packaging5mg
  • Price$258.5
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number30619
  • Product descriptionPD 180970 ≥98%
  • Packaging10mg
  • Price$236
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number30619
  • Product descriptionPD 180970 ≥98%
  • Packaging5mg
  • Price$128
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00BHTP PD 180970 ≥98% 1mg $36 2026-05-28 Buy
aablocks AA00BHTP PD 180970 5mg $63 2026-05-28 Buy
aablocks AA00BHTP PD 180970 10mg $91 2026-05-28 Buy
aablocks AA00BHTP PD 180970 25mg $138 2026-05-28 Buy
aablocks AA00BHTP PD 180970 50mg $197 2026-05-28 Buy
ACHEMBLOCK Y227381 PD180970 97.00% 25MG $175 2026-05-27 Buy
ACHEMBLOCK Y227381 PD180970 97.00% 100MG $525 2026-05-27 Buy
AK Scientific 2636BB 6-(2,6-Dichlorophenyl)-2-[(4-Fluoro-3-Methylphenyl)amino]-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One 1mg $133 2021-12-16 Buy
ApexBio Technology A8606 PD 180970 10mg $231 2026-05-06 Buy
Axon Medchem Axon1137 PD180970 10mg $143 2026-05-19 Buy
Axon Medchem Axon1137 PD180970 50mg $506 2026-05-19 Buy
Biosynth FD102315 PD-180970 10mg $439.5 2026-06-04 Buy
Biosynth FD102315 PD-180970 25mg $879 2026-06-04 Buy
Biosynth FD102315 PD-180970 5mg $258.5 2026-06-04 Buy
Cayman Chemical 30619 PD 180970 ≥98% 10mg $236 2026-04-30 Buy
Cayman Chemical 30619 PD 180970 ≥98% 5mg $128 2026-04-30 Buy

Properties

Boiling point :590.6±60.0 °C(Predicted)
Density :1.449±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :3.02±0.20(Predicted)
form :A solid
color :yellow
InChI :1S/C21H15Cl2FN4O/c1-11-8-13(6-7-17(11)24)26-21-25-10-12-9-14(20(29)28(2)19(12)27-21)18-15(22)4-3-5-16(18)23/h3-10H,1-2H3,(H,25,26,27)
InChIKey :SLCFEJAMCRLYRG-UHFFFAOYSA-N
SMILES :CN1C(=O)C(=Cc2cnc(Nc3ccc(F)c(C)c3)nc12)c4c(Cl)cccc4Cl

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.

Description

PD 180970 is an ATP-competitive inhibitor of p210 tyrosine kinase which selectively induces apoptosis in chronic myeloid leukemia (CML) K562 cells.

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