Delta9-tetrahydrocannabivarin

Properties

Safety Information

Description

Tetrahydrocannabivarin is the propyl analog of Δ9-THC found naturally in Cannabis that acts as a central cannabinoid receptor type 1 (CB1) antagonist (Ki = 75.4 nM) and peripheral cannabinoid (CB2) partial agonist (Ki = 62.8 nM). It also activates transient receptor potential (TRP) channels of the ankyrin type-1 (TRPA1), vanilloid type-1 (TRPV1), and TRPV2 (EC50s = 1.5, 1.5, and 4.1 μM, respectively) and acts as an antagonist of TRPM8 (IC50 = 0.87 μM). This product is intended for forensic and research applications.

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