Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone price.
  • $30 - $2839
  • Product name: 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
  • CAS: 314245-33-5
  • MF: C18H21FN2O
  • MW: 300.37
  • EINECS:232-983-9
  • MDL Number:MFCD01917473
  • Synonyms:1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone;1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE;IU1;1-(1-(4-fluorophenyl)-2,5-diMethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone;Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-;IU1; IU-1; IU 1;IU-1 (USP14 inhibitor IU1);CS-1901;1-[1-(4-Fluorophenyl)-2,5-dimethylpyrrol-3-yl]-2-(pyrrolidin-1-yl)ethanone
Price68 Properties Safety Information Description
68 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 10mM(1mLinDMSO)
  • 10mM(in1mLDMSO)
  • 200mg
  • 250mg
  • 1G
  • 5G
  • 10mM(in 1mL DMSO)
  • 2.5G
  • Manufactureraablocks
  • Product numberAA00C0TR
  • Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone ≥98%
  • Packaging5mg
  • Price$42
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C0TR
  • Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
  • Packaging10mg
  • Price$81
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C0TR
  • Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
  • Packaging25mg
  • Price$137
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C0TR
  • Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
  • Packaging50mg
  • Price$222
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C0TR
  • Product description1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone
  • Packaging100mg
  • Price$379
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15308
  • Product descriptionIU1 98%
  • Packaging100MG
  • Price$350
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15308
  • Product descriptionIU1 98%
  • Packaging25MG
  • Price$130
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15308
  • Product descriptionIU1 98%
  • Packaging5MG
  • Price$50
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15308
  • Product descriptionIU1 98%
  • Packaging1G
  • Price$1250
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5673
  • Product descriptionIU1
  • Packaging100mg
  • Price$1174
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5673
  • Product descriptionIU1
  • Packaging10mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001404
  • Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
  • Packaging5MG
  • Price$401.06
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001404
  • Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
  • Packaging5G
  • Price$1018
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001404
  • Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
  • Packaging2.5G
  • Price$818
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001404
  • Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
  • Packaging1G
  • Price$613
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4002
  • Product descriptionIU1
  • Packaging50mg
  • Price$220
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C0TR 1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone ≥98% 5mg $42 2026-05-28 Buy
aablocks AA00C0TR 1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone 10mg $81 2026-05-28 Buy
aablocks AA00C0TR 1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone 25mg $137 2026-05-28 Buy
aablocks AA00C0TR 1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone 50mg $222 2026-05-28 Buy
aablocks AA00C0TR 1-(1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone 100mg $379 2026-05-28 Buy
ACHEMBLOCK M15308 IU1 98% 100MG $350 2026-05-27 Buy
ACHEMBLOCK M15308 IU1 98% 25MG $130 2026-05-27 Buy
ACHEMBLOCK M15308 IU1 98% 5MG $50 2026-05-27 Buy
ACHEMBLOCK M15308 IU1 98% 1G $1250 2026-05-27 Buy
AK Scientific SYN5673 IU1 100mg $1174 2021-12-16 Buy
AK Scientific SYN5673 IU1 10mg $198 2021-12-16 Buy
American Custom Chemicals Corporation INB0001404 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% 5MG $401.06 2021-12-16 Buy
American Custom Chemicals Corporation INB0001404 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% 5G $1018 2021-12-16 Buy
American Custom Chemicals Corporation INB0001404 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% 2.5G $818 2021-12-16 Buy
American Custom Chemicals Corporation INB0001404 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% 1G $613 2021-12-16 Buy
ApexBio Technology A4002 IU1 50mg $220 2026-05-06 Buy
Next Last

Properties

Boiling point :437.0±45.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :powder
pka :8.20±0.20(Predicted)
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
InChIKey :JUWDSDKJBMFLHE-UHFFFAOYSA-N
SMILES :FC1=CC=C(N2C(C)=CC(C(CN3CCCC3)=O)=C2C)C=C1

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Polybiquitinylation designates proteins for proteasomal degradation. USP14 is one of several deubiquitinating enzymes (DUBs) responsible for shortening proteasome-bound ubiquitin chains, which is known to antagonize the degradation of ubiquitin-protein conjugates. IU1 is a reversible, small molecule inhibitor of deubiquitination by USP14 that demonstrates an IC50 value of 4-5 μM. IU1 selectively stimulates ubiquitin-dependent protein degradation in vitro at 34 μM and in MEF cells at 50 μM. At 75 μM, IU1 reduces accumulation of oxidized proteins in HEK293 cells, alleviating cytotoxicity induced by oxidative stress.

More related product prices

P-5091 Pictilisib (GDC-0941) NSC697923 PR-619 587841-73-4 MG-132 NSC632839hydrochloride ZPCK 1262888-28-7 WP1130

Related product price

Suppliers and manufacturers

Dideu Industries Group Limited
IU1
$1.10
IU1 CAS:314245-33-5
career henan chemical co
1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
$7.00
1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone CAS:314245-33-5
ATK CHEMICAL COMPANY LIMITED
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
Chongqing Chemdad Co., Ltd 3B Pharmachem (Wuhan) International Co.,Ltd. WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. Jinan Trio PharmaTech Co., Ltd.