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ChemicalBook >> CAS DataBase List >> Methyl phosphorodichloridite

Methyl phosphorodichloridite

Methyl phosphorodichloridite price.
  • $28 - $2600
  • Product name: Methyl phosphorodichloridite
  • CAS: 3279-26-3
  • MF: CH3Cl2OP
  • MW: 132.91
  • EINECS:221-915-3
  • MDL Number:MFCD00000524
  • Synonyms:METHYL DICHLOROPHOSPHITE, TECHNICAL GRADE;O-Methyl Phosphorodichloridite;Methoxydichlorophosphine;Methoxyphosphonous Dichloride;O-Methyl Phosphorodichloridit;Methyl Dichlorophosphite [Phosphitylating Agent];Methyl dichlorophosphite,98%;Methyl dichlorophosphite, 98% 5ML
Price20 Properties Safety Information Description
20 prices
Selected condition：
Brand
  • aablocks
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 1g
  • 5g
  • 10g
  • 25G
  • 50g
  • 100g
  • 250G
  • Manufactureraablocks
  • Product numberAA003RZC
  • Product descriptionMethyl Dichlorophosphite 95%
  • Packaging1g
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003RZC
  • Product descriptionMethyl Dichlorophosphite 95%
  • Packaging5g
  • Price$140
  • Updated2026-05-28
  • Buy
  • ManufacturerAHH
  • Product numberMT-18663
  • Product descriptionMethyl phosphorodichloridite 97%
  • Packaging50g
  • Price$295
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7327
  • Product descriptionMethyl dichlorophosphite
  • Packaging10g
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0014736
  • Product descriptionMETHYL DICHLOROPHOSPHITE 95.00%
  • Packaging250G
  • Price$2600
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0014736
  • Product descriptionMETHYL DICHLOROPHOSPHITE 95.00%
  • Packaging5G
  • Price$475
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0014736
  • Product descriptionMETHYL DICHLOROPHOSPHITE 95.00%
  • Packaging25G
  • Price$675
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR929489
  • Product descriptionMethyl phosphorodichloridite 95%
  • Packaging1g
  • Price$28
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR929489
  • Product descriptionMethylphosphorodichloridite 95%
  • Packaging10g
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR929489
  • Product descriptionMethyl phosphorodichloridite 95%
  • Packaging5g
  • Price$90
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFM03057
  • Product descriptionMethyl dichlorophosphite
  • Packaging10g
  • Price$900
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFM03057
  • Product descriptionMethyl dichlorophosphite
  • Packaging25g
  • Price$900
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFM03057
  • Product descriptionMethyl dichlorophosphite
  • Packaging5g
  • Price$900
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFM03057
  • Product descriptionMethyl dichlorophosphite
  • Packaging50g
  • Price$973.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFM03057
  • Product descriptionMethyl dichlorophosphite
  • Packaging100g
  • Price$1622
  • Updated2026-06-04
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number9311
  • Product descriptionDichloroMethylPhosphite
  • Packaging10g
  • Price$190
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003RZC Methyl Dichlorophosphite 95% 1g $52 2026-05-28 Buy
aablocks AA003RZC Methyl Dichlorophosphite 95% 5g $140 2026-05-28 Buy
AHH MT-18663 Methyl phosphorodichloridite 97% 50g $295 2026-05-26 Buy
AK Scientific X7327 Methyl dichlorophosphite 10g $175 2021-12-16 Buy
American Custom Chemicals Corporation ING0014736 METHYL DICHLOROPHOSPHITE 95.00% 250G $2600 2021-12-16 Buy
American Custom Chemicals Corporation ING0014736 METHYL DICHLOROPHOSPHITE 95.00% 5G $475 2021-12-16 Buy
American Custom Chemicals Corporation ING0014736 METHYL DICHLOROPHOSPHITE 95.00% 25G $675 2021-12-16 Buy
Apolloscientific OR929489 Methyl phosphorodichloridite 95% 1g $28 2026-06-04 Buy
Apolloscientific OR929489 Methylphosphorodichloridite 95% 10g $218 2021-12-16 Buy
Apolloscientific OR929489 Methyl phosphorodichloridite 95% 5g $90 2026-06-04 Buy
Biosynth FM03057 Methyl dichlorophosphite 10g $900 2026-06-04 Buy
Biosynth FM03057 Methyl dichlorophosphite 25g $900 2026-06-04 Buy
Biosynth FM03057 Methyl dichlorophosphite 5g $900 2026-06-04 Buy
Biosynth FM03057 Methyl dichlorophosphite 50g $973.5 2026-06-04 Buy
Biosynth FM03057 Methyl dichlorophosphite 100g $1622 2026-06-04 Buy
Medical Isotopes, Inc. 9311 DichloroMethylPhosphite 10g $190 2021-12-16 Buy
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Properties

Melting point :-91 °C (lit.)
Boiling point :93-95 °C (lit.)
Density :1.376 g/mL at 20 °C (lit.)
refractive index :n20/D 1.474(lit.)
Flash point :104 °F
storage temp. :−20°C
solubility :soluble in Chloroform, Dichloromethane, Ethyl Acetate
form :liquid
color :Colorless to Almost colorless
Water Solubility :Reacts with water. Soluble in chloroform, dichloromethane and ethyl acetate.
Sensitive :Moisture Sensitive
BRN :1697452
Stability :Flammable.
InChI :1S/CH3Cl2OP/c1-4-5(2)3/h1H3
InChIKey :HCSDJECSMANTCX-UHFFFAOYSA-N
SMILES :COP(Cl)Cl
CAS DataBase Reference :3279-26-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): Flame (GHS02)Corrosion (GHS05)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methyl phosphorodichloridite is a reagent for the phosphite coupling method of oligonucleotide synthesis. It is employed in the preparation of phosphonamidate- and phosphonate-linked phosphonopeptides, 2-(2-iodophenyl)ethyl methyl phosphite derivative of an alcohol, deoxyoligonucleotides on a polymer support, cis- and trans-2-oxo-2-propionyl-1,3,2-oxazaphosphorinane, phosphorodichloridothioates and oxazaphosphorinanes.

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. Alfa Aesar TCI (Shanghai) Development Co., Ltd. Energy Chemical Shanghai Longsheng chemical Co.,Ltd. Shanghai Hanhong Scientific Co.,Ltd. Chemsky（shanghai）International Co.,Ltd. Shandong Xiya Chemical Co., Ltd Syntechem Co.,Ltd