2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE
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- $28 - $1000
- Product name: 2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE
- CAS: 349085-38-7
- MF: C18H21N5O3
- MW: 355.39
- EINECS:
- MDL Number:MFCD02007349
- Synonyms:2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE;HC 030031;2-(1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)-N-(4-isopropylphenyl)acetamide;1,2,3,6-Tetrahydro-1,3-diMethyl-N-[4-(1-Methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetaMide;7H-Purine-7-acetamide, 1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-;HC-030031;HC 030031;HC030031;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide;HC 030031 1G
64 prices
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 25MG
- 500mg
- 50
- 1 unit
- 10
- 10 mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 10mg
- 50mg
- 100mg
- 200mg
- 250MG
- 1g
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA0037KL
- Product description1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide ≥98%
- Packaging5mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037KL
- Product description1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide ≥98%
- Packaging10mg
- Price$53
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037KL
- Product description1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide
- Packaging50mg
- Price$98
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037KL
- Product description1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide
- Packaging100mg
- Price$139
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037KL
- Product description1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide
- Packaging200mg
- Price$176
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037KL
- Product description1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide ≥98%
- Packaging1g
- Price$877
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10329
- Product descriptionHC-030031 98%
- Packaging250MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10329
- Product descriptionHC-030031 98%
- Packaging1G
- Price$730
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2459AH
- Product description2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2100
- Product descriptionHC-030031
- Packaging50mg
- Price$121
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB2100
- Product descriptionHC-030031
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB2100
- Product descriptionHC-030031
- Packaging10mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB2100
- Product descriptionHC-030031
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-15064
- Product descriptionHC-030031 99.65%
- Packaging5mg
- Price$34
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15064
- Product descriptionHC-030031 99.65%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$35
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15064
- Product descriptionHC-030031 99.65%
- Packaging10mM*1mLinDMSO(Solution)
- Price$37
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0037KL | 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide ≥98% | 5mg | $31 | 2026-05-28 | Buy |
| aablocks | AA0037KL | 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide ≥98% | 10mg | $53 | 2026-05-28 | Buy |
| aablocks | AA0037KL | 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide | 50mg | $98 | 2026-05-28 | Buy |
| aablocks | AA0037KL | 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide | 100mg | $139 | 2026-05-28 | Buy |
| aablocks | AA0037KL | 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide | 200mg | $176 | 2026-05-28 | Buy |
| aablocks | AA0037KL | 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide ≥98% | 1g | $877 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10329 | HC-030031 98% | 250MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10329 | HC-030031 98% | 1G | $730 | 2026-05-27 | Buy |
| AK Scientific | 2459AH | 2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide | 10mg | $137 | 2021-12-16 | Buy |
| ApexBio Technology | B2100 | HC-030031 | 50mg | $121 | 2026-05-06 | Buy |
| ApexBio Technology | B2100 | HC-030031 | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | B2100 | HC-030031 | 10mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | B2100 | HC-030031 | 10mg | $45 | 2021-12-16 | Buy |
| Arctom | HY-15064 | HC-030031 99.65% | 5mg | $34 | 2026-05-26 | Buy |
| Arctom | HY-15064 | HC-030031 99.65% | 10mM*1mLinDMSO(Solid+Solvent) | $35 | 2026-05-26 | Buy |
| Arctom | HY-15064 | HC-030031 99.65% | 10mM*1mLinDMSO(Solution) | $37 | 2026-05-26 | Buy |
Properties
Melting point :221-223°C
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble10mg/mL, clear
form :White solid
pka :13.71±0.70(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C18H21N5O3/c1-11(2)12-5-7-13(8-6-12)20-14(24)9-23-10-19-16-15(23)17(25)22(4)18(26)21(16)3/h5-8,10-11H,9H2,1-4H3,(H,20,24)
InChIKey :HEQDZPHDVAOBLN-UHFFFAOYSA-N
SMILES :N1(CC(NC2=CC=C(C(C)C)C=C2)=O)C2=C(N(C)C(=O)N(C)C2=O)N=C1
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble10mg/mL, clear
form :White solid
pka :13.71±0.70(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C18H21N5O3/c1-11(2)12-5-7-13(8-6-12)20-14(24)9-23-10-19-16-15(23)17(25)22(4)18(26)21(16)3/h5-8,10-11H,9H2,1-4H3,(H,20,24)
InChIKey :HEQDZPHDVAOBLN-UHFFFAOYSA-N
SMILES :N1(CC(NC2=CC=C(C(C)C)C=C2)=O)C2=C(N(C)C(=O)N(C)C2=O)N=C1
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
Transient receptor potential cation channel A1 (TRPA1) is an ankyrin-like ion channel which acts as a sensor for chemical irritants, pain, and cold. It is activated by allyl isothiocyanate (AITC), formalin, hydrogen peroxide, tear gas, and other compounds. HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 μM, respectively). It does not block currents mediated by TRPV1, TRPV3, TRPV4 hERG, or NaV1.2 channels. HC-030031 can be used in cells or delivered to animals orally, by inhalation, or by injection. Oral administration (100 mg/kg) of HC-030031 significantly reversed mechanical hypersensitivity in rat models of chronic inflammatory or neuropathic pain, while local injection (100 μg) into inflamed mouse hind paws attenuated mechanical, but not heat, hypersensitivity.More related product prices
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