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ChemicalBook >> CAS DataBase List >> 1-benzyl-3-(4-chlorophenyl)-5-MethyliMidazolidine-2,4-dione

1-benzyl-3-(4-chlorophenyl)-5-MethyliMidazolidine-2,4-dione

1-benzyl-3-(4-chlorophenyl)-5-MethyliMidazolidine-2,4-dione price.
  • $41 - $1900
  • Product name: 1-benzyl-3-(4-chlorophenyl)-5-MethyliMidazolidine-2,4-dione
  • CAS: 37468-32-9
  • MF: C17H15ClN2O2
  • MW: 314.77
  • EINECS:
  • MDL Number:MFCD19441284
  • Synonyms:1-benzyl-3-(4-chlorophenyl)-5-MethyliMidazolidine-2,4-dione;3-(4-Chlorophenyl)-5-methyl-1-(phenylmethyl)-2,4-Imidazolidinedione;2,4-Imidazolidinedione, 3-(4-chlorophenyl)-5-methyl-1-(phenylmethyl)-;ALLO1,ALLO 1;ALLO-1
21 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00C9MX
  • Product descriptionALLO-1 ≥98%
  • Packaging5mg
  • Price$108
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MX
  • Product descriptionALLO-1 98%byHPLC
  • Packaging10mg
  • Price$180
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MX
  • Product descriptionALLO-1 98%byHPLC
  • Packaging25mg
  • Price$331
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MX
  • Product descriptionALLO-1 98%byHPLC
  • Packaging50mg
  • Price$533
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MX
  • Product descriptionALLO-1 98%byHPLC
  • Packaging100mg
  • Price$889
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5263
  • Product descriptionALLO-1
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4582
  • Product descriptionALLO-1
  • Packaging25mg
  • Price$602
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4582
  • Product descriptionALLO-1
  • Packaging10mg
  • Price$267
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4582
  • Product descriptionALLO-1
  • Packaging5mg
  • Price$148
  • Updated2026-05-06
  • Buy
  • ManufacturerCayman Chemical
  • Product number17776
  • Product descriptionALLO-1 ≥98%
  • Packaging5mg
  • Price$108
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number17776
  • Product descriptionALLO-1 ≥98%
  • Packaging10mg
  • Price$196
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number17776
  • Product descriptionALLO-1 ≥98%
  • Packaging1mg
  • Price$41
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number17776
  • Product descriptionALLO-1 ≥98%
  • Packaging25mg
  • Price$437
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0082726
  • Product descriptionALLO-1
  • Packaging1mg
  • Price$93
  • Updated2026-06-04
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8570
  • Product descriptionALLO-1 >98%
  • Packaging100mg
  • Price$450
  • Updated2026-05-24
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8570
  • Product descriptionALLO-1 >98%
  • Packaging1g
  • Price$1900
  • Updated2026-05-24
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C9MX ALLO-1 ≥98% 5mg $108 2026-05-28 Buy
aablocks AA00C9MX ALLO-1 98%byHPLC 10mg $180 2026-05-28 Buy
aablocks AA00C9MX ALLO-1 98%byHPLC 25mg $331 2026-05-28 Buy
aablocks AA00C9MX ALLO-1 98%byHPLC 50mg $533 2026-05-28 Buy
aablocks AA00C9MX ALLO-1 98%byHPLC 100mg $889 2026-05-28 Buy
AK Scientific SYN5263 ALLO-1 10mg $160 2021-12-16 Buy
ApexBio Technology C4582 ALLO-1 25mg $602 2026-05-06 Buy
ApexBio Technology C4582 ALLO-1 10mg $267 2026-05-06 Buy
ApexBio Technology C4582 ALLO-1 5mg $148 2026-05-06 Buy
Cayman Chemical 17776 ALLO-1 ≥98% 5mg $108 2026-04-30 Buy
Cayman Chemical 17776 ALLO-1 ≥98% 10mg $196 2026-04-30 Buy
Cayman Chemical 17776 ALLO-1 ≥98% 1mg $41 2026-04-30 Buy
Cayman Chemical 17776 ALLO-1 ≥98% 25mg $437 2026-04-30 Buy
ChemScene CS-0082726 ALLO-1 1mg $93 2026-06-04 Buy
DC Chemicals DC8570 ALLO-1 >98% 100mg $450 2026-05-24 Buy
DC Chemicals DC8570 ALLO-1 >98% 1g $1900 2026-05-24 Buy

Properties

Boiling point :452.0±55.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :-1.30±0.40(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Hedgehog (Hh) proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of the GPCR-like receptor, Smoothened (SMO). In vertebrates, this ultimately leads to the activation of the zinc-finger transcription factors of the Gli family. Overactivation of this pathway contributes to certain cancers. ALLO-1 is a SMO antagonist that inhibits both wild-type (IC50 = 50 nM) and mutant SMO, including the D473H SMO mutant (IC50s = 300-1000 nM). This compound binds to the SMO cysteine-rich domain, which is a different mechanism of interaction compared to other known SMO ligands that bind the transmembrane pocket.