3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide
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- $32 - $1500
- Product name: 3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide
- CAS: 420831-40-9
- MF: C19H21BrN2O3S
- MW: 437.35
- EINECS:
- MDL Number:MFCD03140195
- Synonyms:N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide;SIRT2 Inhibitor,AK-7;N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide SIRT2 Inhibitor,AK-7;SIRT2 Inhibitor II;SIRT2 INHIBITOR II;AK7;AK 7;AK 7, >=98%;3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide;AK-7
69 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO
- 100MG
- 50
- 10mM*1mLinDMSO(Solid+Solvent)
- 250mg
- 1g
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA00C0UC
- Product description3-(Azepan-1-Ylsulfonyl)-N-(3-Bromophenyl)Benzamide ≥98%
- Packaging5mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UC
- Product description3-(Azepan-1-Ylsulfonyl)-N-(3-Bromophenyl)Benzamide 99%
- Packaging25mg
- Price$84
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UC
- Product description3-(Azepan-1-Ylsulfonyl)-N-(3-Bromophenyl)Benzamide 99%
- Packaging50mg
- Price$139
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16070
- Product descriptionAK-7 98%
- Packaging25MG
- Price$130
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16070
- Product descriptionAK-7 98%
- Packaging100MG
- Price$380
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3511-M005
- Product descriptionAK-7 ≥98%(NMR)
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3511-M005
- Product descriptionAK-7 ≥98%(NMR)
- Packaging5mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3511-M025
- Product descriptionAK-7 ≥98%(NMR)
- Packaging25mg
- Price$240
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberY1898
- Product description3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1898
- Product description3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide
- Packaging250mg
- Price$1169
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA566314
- Product descriptionAK-7 98+%
- Packaging25mg
- Price$287
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA566314
- Product descriptionAK-7 98+%
- Packaging50mg
- Price$373
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA566314
- Product descriptionAK-7 98+%
- Packaging10mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4713
- Product descriptionAK-7
- Packaging10mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4713
- Product descriptionAK-7
- Packaging10mg
- Price$149
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4713
- Product descriptionAK-7
- Packaging100mg
- Price$771
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C0UC | 3-(Azepan-1-Ylsulfonyl)-N-(3-Bromophenyl)Benzamide ≥98% | 5mg | $32 | 2026-05-28 | Buy |
| aablocks | AA00C0UC | 3-(Azepan-1-Ylsulfonyl)-N-(3-Bromophenyl)Benzamide 99% | 25mg | $84 | 2026-05-28 | Buy |
| aablocks | AA00C0UC | 3-(Azepan-1-Ylsulfonyl)-N-(3-Bromophenyl)Benzamide 99% | 50mg | $139 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16070 | AK-7 98% | 25MG | $130 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16070 | AK-7 98% | 100MG | $380 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3511-M005 | AK-7 ≥98%(NMR) | 5mg | $80 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3511-M005 | AK-7 ≥98%(NMR) | 5mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3511-M025 | AK-7 ≥98%(NMR) | 25mg | $240 | 2026-05-06 | Buy |
| AK Scientific | Y1898 | 3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide | 10mg | $192 | 2021-12-16 | Buy |
| AK Scientific | Y1898 | 3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide | 250mg | $1169 | 2021-12-16 | Buy |
| Ambeed | A566314 | AK-7 98+% | 25mg | $287 | 2021-12-16 | Buy |
| Ambeed | A566314 | AK-7 98+% | 50mg | $373 | 2021-12-16 | Buy |
| Ambeed | A566314 | AK-7 98+% | 10mg | $169 | 2021-12-16 | Buy |
| ApexBio Technology | B4713 | AK-7 | 10mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B4713 | AK-7 | 10mg | $149 | 2026-05-06 | Buy |
| ApexBio Technology | B4713 | AK-7 | 100mg | $771 | 2026-05-06 | Buy |
Properties
Density :1.469±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥15mg/mL
form :powder
pka :12.28±0.70(Predicted)
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C19H21BrN2O3S/c20-16-8-6-9-17(14-16)21-19(23)15-7-5-10-18(13-15)26(24,25)22-11-3-1-2-4-12-22/h5-10,13-14H,1-4,11-12H2,(H,21,23)
InChIKey :IYAYHZZWYNXHEQ-UHFFFAOYSA-N
SMILES :C(NC1=CC=CC(Br)=C1)(=O)C1=CC=CC(S(N2CCCCCC2)(=O)=O)=C1
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥15mg/mL
form :powder
pka :12.28±0.70(Predicted)
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C19H21BrN2O3S/c20-16-8-6-9-17(14-16)21-19(23)15-7-5-10-18(13-15)26(24,25)22-11-3-1-2-4-12-22/h5-10,13-14H,1-4,11-12H2,(H,21,23)
InChIKey :IYAYHZZWYNXHEQ-UHFFFAOYSA-N
SMILES :C(NC1=CC=CC(Br)=C1)(=O)C1=CC=CC(S(N2CCCCCC2)(=O)=O)=C1
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
The sirtuin SIRT2 is a deacetylase which targets α-tubulin, histone 4, forkhead transcription factors, and several other substrates. It has roles in metabolic diseases, cancer, age-related disorders, and neurodegenerative diseases, potentially including Alzheimer’s, Huntington’s, and Parkinson’s diseases. AK-7 is a cell- and brain-permeable inhibitor of SIRT2 (IC50 = 15.5 μM). In culture, it dimishes neuronal cell death induced by mutant huntingtin fragment. In addition, AK-7 down-regulates cholesterol biosynthetic gene expression and reduces total cholesterol levels in neurons in vivo.More related product prices
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