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ChemicalBook >> CAS DataBase List >> (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one price.
  • $6 - $910
  • Product name: (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
  • CAS: 42399-49-5
  • MF: C16H15NO3S
  • MW: 301.36
  • EINECS:255-799-0
  • MDL Number:MFCD01321316
  • Synonyms:HYDROXY LACTAM;(2S-CIS)-(+)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE;(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one ,99%;DiltiazeM IMpurity E;3-hydroxy-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one;(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one;(2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one;Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem
Price30 Properties Safety Information Description
30 prices
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Brand
  • aablocks
  • AK Scientific
  • Alichem
  • Ambeed
  • Biosynth
  • Chemenu
  • Chem-Impex
  • Crysdot
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  • TCI Chemical
  • TRC
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  • Manufactureraablocks
  • Product numberAA00329Q
  • Product description(2S-Cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one 97%
  • Packaging5g
  • Price$10
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00329Q
  • Product description(2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 99%
  • Packaging25g
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00329Q
  • Product description(2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 99%
  • Packaging100g
  • Price$27
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00329Q
  • Product description(2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 99%
  • Packaging500g
  • Price$93
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11189
  • Product descriptionDiltiazemImpurityE
  • Packaging5mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number42399495
  • Product description(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
  • Packaging100g
  • Price$166.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156981
  • Product description(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+%
  • Packaging100g
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156981
  • Product description(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+%
  • Packaging25g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156981
  • Product description(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+%
  • Packaging500g
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156981
  • Product description(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFD21106
  • Product descriptionDes[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem
  • Packaging25g
  • Price$150
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD21106
  • Product descriptionDes[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem
  • Packaging50g
  • Price$172.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD21106
  • Product descriptionDes[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem
  • Packaging100g
  • Price$290
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD21106
  • Product descriptionDes[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem
  • Packaging250g
  • Price$542.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFD21106
  • Product descriptionDes[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem
  • Packaging500g
  • Price$910
  • Updated2026-06-04
  • Buy
  • ManufacturerChemenu
  • Product numberCM160164
  • Product description(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 95%
  • Packaging100g
  • Price$173
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00329Q (2S-Cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5h)-one 97% 5g $10 2021-12-16 Buy
aablocks AA00329Q (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 99% 25g $10 2026-05-28 Buy
aablocks AA00329Q (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 99% 100g $27 2026-05-28 Buy
aablocks AA00329Q (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 99% 500g $93 2026-05-28 Buy
AK Scientific J11189 DiltiazemImpurityE 5mg $36 2021-12-16 Buy
Alichem 42399495 (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 100g $166.6 2021-12-16 Buy
Ambeed A156981 (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+% 100g $31 2021-12-16 Buy
Ambeed A156981 (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+% 25g $11 2021-12-16 Buy
Ambeed A156981 (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+% 500g $106 2021-12-16 Buy
Ambeed A156981 (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 99+% 5g $6 2021-12-16 Buy
Biosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 25g $150 2026-06-04 Buy
Biosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 50g $172.5 2026-06-04 Buy
Biosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 100g $290 2026-06-04 Buy
Biosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 250g $542.5 2026-06-04 Buy
Biosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 500g $910 2026-06-04 Buy
Chemenu CM160164 (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one 95% 100g $173 2021-12-16 Buy
Next Last

Properties

Melting point :203-206 °C(lit.)
alpha :112 º (c=0.5 in MeOH)
Boiling point :545.4±50.0 °C(Predicted)
Density :1.2458 (rough estimate)
refractive index :114 ° (C=0.5, MeOH)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :12.37±0.40(Predicted)
color :Off-White
InChI :InChI=1S/C16H15NO3S/c1-20-11-8-6-10(7-9-11)15-14(18)16(19)17-12-4-2-3-5-13(12)21-15/h2-9,14-15,18H,1H3,(H,17,19)/t14-,15+/m1/s1
InChIKey :LHBHZALHFIQJGJ-CABCVRRESA-N
SMILES :S1C2=CC=CC=C2NC(=O)[C@H](O)[C@@H]1C1=CC=C(OC)C=C1
CAS DataBase Reference :42399-49-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

A key intermediate used for Diltiazem synthesis.

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Suppliers and manufacturers

Suzhou Kaiyuan Minsheng Sci&Tech Corp. Ltd. Shengbaolai Biotechnology Co., Ltd J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. TCI (Shanghai) Development Co., Ltd. Energy Chemical Adamas Reagent, Ltd. Shanghai Longsheng chemical Co.,Ltd. Nanjing Chemlin Chemical Co., Ltd Chemsky（shanghai）International Co.,Ltd.