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ChemicalBook >> CAS DataBase List >> 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE

4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE

4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE price.
  • $6 - $3510
  • Product name: 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE
  • CAS: 426844-51-1
  • MF: C5H9ClF2N2O
  • MW: 186.59
  • EINECS:
  • MDL Number:MFCD06797014
  • Synonyms:(2S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride;4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE;-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride;4,4-Difluoro-l-prolinaMide, HCl;(S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride;(S)-4,4-difluoropyrrolidine-2-carboxamide HCl;(2S)-4,4-difluoro-2-pyrrolidinecarboxamide, HCl;(2S)-4,4-difluoropyrrolidine-2-carboxamide
Price58 Properties Safety Information Description
58 prices
Selected condition：
Brand
  • aablocks
  • Abosyn
  • ACHEMBLOCK
  • Activate Scientific
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth
  • Chemenu
  • Chem-Impex
  • Crysdot
  • Matrix Scientific
  • Sigma-Aldrich
  • SynQuest Laboratories
  • Synthonix
  • Thermo Scientific Chemicals
  • TRC
  • Usbiological
Package
  • 100mg
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  • 1g
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  • 2.5g
  • 5.00g
  • 5g
  • 10.00g
  • 10g
  • 25g
  • Manufactureraablocks
  • Product numberAA003CJI
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97%
  • Packaging10g
  • Price$98
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CJI
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97%
  • Packaging25g
  • Price$225
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CJI
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97%
  • Packaging1g
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CJI
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97%
  • Packaging250mg
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CJI
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97%
  • Packaging100mg
  • Price$6
  • Updated2026-05-28
  • Buy
  • ManufacturerAbosyn
  • Product number90-6736
  • Product description4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE 95+(Puritymayvarybetweenbatches)
  • Packaging5g
  • Price$80
  • Updated2026-05-21
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS75579
  • Product description(2S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride 97%
  • Packaging25G
  • Price$255
  • Updated2026-05-27
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS110236
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% ee
  • Packaging1g
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS110236
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% ee
  • Packaging5G
  • Price$582
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV5909
  • Product description4,4-Difluoro-L-prolinamide hydrochloride
  • Packaging500mg
  • Price$163
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number426844511
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamidehydrochloride
  • Packaging5g
  • Price$634.94
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number426844511
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamidehydrochloride
  • Packaging10g
  • Price$656.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number426844511
  • Product description(S)-4,4-Difluoropyrrolidine-2-carboxamidehydrochloride
  • Packaging25g
  • Price$1280
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0012766
  • Product description4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE 95.00%
  • Packaging5G
  • Price$1237.01
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0012766
  • Product description4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$715.52
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC409000
  • Product description4,4-Difluoro-L-Prolinamide hydrochloride 97%
  • Packaging25g
  • Price$515
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003CJI (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% 10g $98 2026-05-28 Buy
aablocks AA003CJI (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% 25g $225 2026-05-28 Buy
aablocks AA003CJI (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% 1g $15 2026-05-28 Buy
aablocks AA003CJI (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% 250mg $12 2026-05-28 Buy
aablocks AA003CJI (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% 100mg $6 2026-05-28 Buy
Abosyn 90-6736 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE 95+(Puritymayvarybetweenbatches) 5g $80 2026-05-21 Buy
ACHEMBLOCK S75579 (2S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride 97% 25G $255 2026-05-27 Buy
Activate Scientific AS110236 (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% ee 1g $218 2021-12-16 Buy
Activate Scientific AS110236 (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride 97% ee 5G $582 2021-12-16 Buy
AK Scientific V5909 4,4-Difluoro-L-prolinamide hydrochloride 500mg $163 2021-12-16 Buy
Alichem 426844511 (S)-4,4-Difluoropyrrolidine-2-carboxamidehydrochloride 5g $634.94 2021-12-16 Buy
Alichem 426844511 (S)-4,4-Difluoropyrrolidine-2-carboxamidehydrochloride 10g $656.5 2021-12-16 Buy
Alichem 426844511 (S)-4,4-Difluoropyrrolidine-2-carboxamidehydrochloride 25g $1280 2021-12-16 Buy
American Custom Chemicals Corporation HCH0012766 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE 95.00% 5G $1237.01 2021-12-16 Buy
American Custom Chemicals Corporation HCH0012766 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE 95.00% 1G $715.52 2021-12-16 Buy
Apolloscientific PC409000 4,4-Difluoro-L-Prolinamide hydrochloride 97% 25g $515 2026-06-04 Buy
Next Last

Properties

Melting point :222°C
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Pale Grey to Light Grey
optical activity :[α]/D 23±5°, c = 0.5 in H2O
InChI :InChI=1/C5H8F2N2O.ClH/c6-5(7)1-3(4(8)10)9-2-5;/h3,9H,1-2H2,(H2,8,10);1H/t3-;/s3
InChIKey :RRQDQYAEZGKHOB-OQFXAWDINA-N
SMILES :C1[C@@H](C(N)=O)NCC1(F)F.Cl |&1:1,r|

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4,4-Difluoro-L-prolinamide hydrochloride can be used as a building block in the synthesis of cyanopyrrolidine based DPP-IV inhibitors.

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Suppliers and manufacturers

Jiangxi Kaixin Biomedical Co., Ltd. Shanghai Lingfu Pharmaceutical Research Co. LTD Aikon International Limited Shanghai AQ BioPharma Co., Ltd. Alfa Aesar Bide Pharmatech Ltd. Shanghai AQBioPharma Co., Ltd. Shanghai Synteam Biochem CO.,ltd Sigma-Aldrich Tongling HengYou Biotechnology Co., Ltd.