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ChemicalBook >> CAS DataBase List >> 5-Fluorocytosine

5-Fluorocytosine

5-Fluorocytosine price.
  • $3 - $1500
  • Product name: 5-Fluorocytosine
  • CAS: 2022-85-7
  • MF: C4H4FN3O
  • MW: 129.09
  • EINECS:217-968-7
  • MDL Number:MFCD00006035
  • Synonyms:4-amino-5-fluoro-2(1h)-pyrimidinon ;4-Amino-5-fluoro-2(1H)-pyrmidinone ;5-fluorocystosine ;5-fluorocytosin ;5-fluoro-cytosin ;fluocytosine ;4-Amino-5-Fluoro-2(1H)-pyrimidine, Flucytosine, 5-FC;5-Fluorocytosine98%
Price126 Properties Safety Information Description
126 prices
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Brand
  • aablocks
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • Usbiological
Package
  • 5MG
  • 10mg
  • 25mg
  • 100mg
  • 200mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 250mg
  • 500mg
  • 1g
  • 10mM*1mLinDMSO(Solution)
  • f0175000
  • y0001262
  • 2.5g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • 100.00g
  • 250g
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  • 1kg
  • 10mM(in1mLDMSO)
  • 500g
  • 10mM(in 1mL DMSO)
  • 4x25g
  • 1000.00g
  • 1000g
  • 2Kg
  • 2000g
  • 5kg
  • 0.3 mg
  • 50 mg
  • Manufactureraablocks
  • Product numberAA002829
  • Product description5-Fluorocytosine 95%
  • Packaging1g
  • Price$3
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002829
  • Product description5-Fluorocytosine 95%
  • Packaging5g
  • Price$4
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002829
  • Product description5-Fluorocytosine 95%
  • Packaging10g
  • Price$5
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA002829
  • Product description5-Fluorocytosine 95%
  • Packaging25g
  • Price$7
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002829
  • Product description5-Fluorocytosine 95%
  • Packaging100g
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002829
  • Product description5-Fluorocytosine 97%
  • Packaging500g
  • Price$87
  • Updated2026-05-28
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-F0077-G001
  • Product description5-Fluorocytosine ≥99%(TLC)
  • Packaging1g
  • Price$141
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-F0077-G001
  • Product description5-Fluorocytosine ≥99%(TLC)
  • Packaging1g
  • Price$158
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-F0077-G005
  • Product description5-Fluorocytosine ≥99%(TLC)
  • Packaging5g
  • Price$631
  • Updated2026-05-06
  • Buy
  • ManufacturerAHH
  • Product numberMT-13095
  • Product description5-Fluorocytosine 98%
  • Packaging100g
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-13095
  • Product description5-Fluorocytosine 97%
  • Packaging100g
  • Price$345
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-13095
  • Product description5-Fluorocytosine 97%
  • Packaging100g
  • Price$345
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberE353
  • Product description5-Fluorocytosine
  • Packaging4x25g
  • Price$67
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ10796
  • Product descriptionFluorocytosine 99%(HPLC),powder
  • Packaging1g
  • Price$95
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberE353
  • Product description5-Fluorocytosine 98%
  • Packaging100g
  • Price$55
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberE353
  • Product description5-Fluorocytosine 98%
  • Packaging25g
  • Price$23
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002829 5-Fluorocytosine 95% 1g $3 2026-05-28 Buy
aablocks AA002829 5-Fluorocytosine 95% 5g $4 2026-05-28 Buy
aablocks AA002829 5-Fluorocytosine 95% 10g $5 2026-05-28 Buy
aablocks AA002829 5-Fluorocytosine 95% 25g $7 2026-05-28 Buy
aablocks AA002829 5-Fluorocytosine 95% 100g $19 2026-05-28 Buy
aablocks AA002829 5-Fluorocytosine 97% 500g $87 2026-05-28 Buy
Adipogen Life Sciences CDX-F0077-G001 5-Fluorocytosine ≥99%(TLC) 1g $141 2021-12-16 Buy
Adipogen Life Sciences CDX-F0077-G001 5-Fluorocytosine ≥99%(TLC) 1g $158 2026-05-06 Buy
Adipogen Life Sciences CDX-F0077-G005 5-Fluorocytosine ≥99%(TLC) 5g $631 2026-05-06 Buy
AHH MT-13095 5-Fluorocytosine 98% 100g $345 2021-12-16 Buy
AHH MT-13095 5-Fluorocytosine 97% 100g $345 2026-05-25 Buy
AHH MT-13095 5-Fluorocytosine 97% 100g $345 2026-05-26 Buy
AK Scientific E353 5-Fluorocytosine 4x25g $67 2021-12-16 Buy
AK Scientific J10796 Fluorocytosine 99%(HPLC),powder 1g $95 2026-06-04 Buy
AK Scientific E353 5-Fluorocytosine 98% 100g $55 2026-06-04 Buy
AK Scientific E353 5-Fluorocytosine 98% 25g $23 2026-06-04 Buy
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Properties

Melting point :298-300 °C (dec.) (lit.)
Density :1.3990 (estimate)
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :Sparingly soluble in water, slightly soluble in ethanol (96 per cent)
form :Crystalline Powder
pka :3.26(at 25℃)
color :White to almost white
Water Solubility :1.5g/100mL (25 ºC)
Sensitive :Light Sensitive
Merck :14,4125
BRN :127285
BCS Class :1
Stability :Light Sensitive
InChI :1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
InChIKey :XRECTZIEBJDKEO-UHFFFAOYSA-N
SMILES :NC1=NC(=O)NC=C1F
LogP :-1.36 at 22.1℃ and pH6.4-6.9
Dissociation constant :2.74-10.71 at 21.4℃
CAS DataBase Reference :2022-85-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

5-Fluorocytosine (5-FC), a fluorinated pyrimidine analog, is a synthetic antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil. 5-fluorouracil, a widely used cytotoxic drug, is further metabolized to fluorinated ribo- and deoxyribonucleotides, resulting in the inhibition of DNA and protein synthesis, which has multiple effects including inhibition of Candida species and C. neoformans infections and cytotoxicity towards cancer cells. In combination with a retroviral replicating vector carrying a cytosine deaminase prodrug-activating gene, 5-FC has been shown to selectively eliminate CT26 and Tu-2449 tumor cells in vitro (IC50s = 4.2 and 1.5 μM, respectively) and to significantly improve survival and reduce tumor size (at a dose of 500 mg/kg) in two different syngeneic mouse glioma models.

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