3-Chloro-5-hydroxy-benzoic acid
|
- $9 - $1460.2
- Product name: 3-Chloro-5-hydroxy-benzoic acid
- CAS: 53984-36-4
- MF: C7H5ClO3
- MW: 172.57
- EINECS:
- MDL Number:MFCD04114327
- Synonyms:5-(hydroxy)-3-chlorobenzoic acid;5-Chloro-m-salicylic Acid;3-chloro-5-hydroxy BA;Benzoic acid, 3-chloro-5-hydroxy-;GPR81 Agonist, 3Cl-5OH-BA ;GPR81 Agonist, 3Cl-5OH-BA - CAS 53984-36-4 - Calbiochem;3-chloro-5-hydroxybenzoic Acid, 10 mM in DMSO;3-Chloro-5-hydroxy-benzoic acid
93 prices
Selected condition：
Brand
- A2B
- aablocks
- ACHEMBLOCK
- Activate Scientific
- AK Scientific
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Atlantic Research Chemicals
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- J&W Pharmlab
- Matrix Scientific
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
Package
- 25mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in 1mL DMSO)
- 500mg
- 10mM*1mLinDMSO(Solution)
- 200mg
- 250mgs:
- 1.00g
- 1mlx10mM(inDMSO)
- 10mM(in1mLDMSO)
- 5MG
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- 25g
- 100G
- ManufacturerA2B
- Product numberAI52093
- Product description3-Chloro-5-hydroxybenzoic acid 97%
- Packaging250mg
- Price$9
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI52093
- Product description3-Chloro-5-hydroxybenzoic acid 97%
- Packaging1g
- Price$14
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI52093
- Product description3-Chloro-5-hydroxybenzoic acid 97%
- Packaging5g
- Price$42
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI52093
- Product description3-Chloro-5-hydroxybenzoic acid 97%
- Packaging10g
- Price$82
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI52093
- Product description3-Chloro-5-hydroxybenzoic acid 97%
- Packaging25g
- Price$189
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00I9K1
- Product description3-Chloro-5-Hydroxybenzoic Acid 95%
- Packaging25g
- Price$214
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I9K1
- Product description3-Chloro-5-Hydroxybenzoic Acid 95%
- Packaging1g
- Price$16
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I9K1
- Product description3-Chloro-5-Hydroxybenzoic Acid 95%
- Packaging250mg
- Price$10
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I9K1
- Product description3-Chloro-5-Hydroxybenzoic Acid 95%
- Packaging10g
- Price$93
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I9K1
- Product description3-Chloro-5-Hydroxybenzoic Acid 95%
- Packaging5g
- Price$48
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberS71255
- Product description3-chloro-5-hydroxybenzoic acid 95%
- Packaging25G
- Price$320
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS71255
- Product description3-chloro-5-hydroxybenzoic acid 95%
- Packaging100G
- Price$960
- Updated2026-05-27
- Buy
- ManufacturerActivate Scientific
- Product numberAS27380
- Product description3-Chloro-5-hydroxybenzoic Acid 96%
- Packaging25g
- Price$622
- Updated2026-06-04
- Buy
- ManufacturerActivate Scientific
- Product numberAS27380
- Product description3-Chloro-5-hydroxybenzoic Acid 96%
- Packaging5g
- Price$198
- Updated2026-06-04
- Buy
- ManufacturerActivate Scientific
- Product numberAS27380
- Product description3-Chloro-5-hydroxybenzoic Acid 96%
- Packaging1g
- Price$62
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberX8059
- Product description3-Chloro-5-hydroxybenzoic acid 98%(HPLC)
- Packaging1g
- Price$35
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A2B | AI52093 | 3-Chloro-5-hydroxybenzoic acid 97% | 250mg | $9 | 2026-05-25 | Buy |
| A2B | AI52093 | 3-Chloro-5-hydroxybenzoic acid 97% | 1g | $14 | 2026-05-25 | Buy |
| A2B | AI52093 | 3-Chloro-5-hydroxybenzoic acid 97% | 5g | $42 | 2026-05-25 | Buy |
| A2B | AI52093 | 3-Chloro-5-hydroxybenzoic acid 97% | 10g | $82 | 2026-05-25 | Buy |
| A2B | AI52093 | 3-Chloro-5-hydroxybenzoic acid 97% | 25g | $189 | 2026-05-25 | Buy |
| aablocks | AA00I9K1 | 3-Chloro-5-Hydroxybenzoic Acid 95% | 25g | $214 | 2026-05-29 | Buy |
| aablocks | AA00I9K1 | 3-Chloro-5-Hydroxybenzoic Acid 95% | 1g | $16 | 2026-05-29 | Buy |
| aablocks | AA00I9K1 | 3-Chloro-5-Hydroxybenzoic Acid 95% | 250mg | $10 | 2026-05-29 | Buy |
| aablocks | AA00I9K1 | 3-Chloro-5-Hydroxybenzoic Acid 95% | 10g | $93 | 2026-05-29 | Buy |
| aablocks | AA00I9K1 | 3-Chloro-5-Hydroxybenzoic Acid 95% | 5g | $48 | 2026-05-29 | Buy |
| ACHEMBLOCK | S71255 | 3-chloro-5-hydroxybenzoic acid 95% | 25G | $320 | 2026-05-27 | Buy |
| ACHEMBLOCK | S71255 | 3-chloro-5-hydroxybenzoic acid 95% | 100G | $960 | 2026-05-27 | Buy |
| Activate Scientific | AS27380 | 3-Chloro-5-hydroxybenzoic Acid 96% | 25g | $622 | 2026-06-04 | Buy |
| Activate Scientific | AS27380 | 3-Chloro-5-hydroxybenzoic Acid 96% | 5g | $198 | 2026-06-04 | Buy |
| Activate Scientific | AS27380 | 3-Chloro-5-hydroxybenzoic Acid 96% | 1g | $62 | 2026-06-04 | Buy |
| AK Scientific | X8059 | 3-Chloro-5-hydroxybenzoic acid 98%(HPLC) | 1g | $35 | 2026-06-04 | Buy |
Properties
Melting point :244.0 to 248.0 °C
Boiling point :364.8±27.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble15mg/mL (clear solution)
pka :3.71±0.10(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C7H5ClO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)
InChIKey :RJOLIYHZZKAIET-UHFFFAOYSA-N
SMILES :C(O)(=O)C1=CC(O)=CC(Cl)=C1
CAS DataBase Reference :53984-36-4
Boiling point :364.8±27.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble15mg/mL (clear solution)
pka :3.71±0.10(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C7H5ClO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)
InChIKey :RJOLIYHZZKAIET-UHFFFAOYSA-N
SMILES :C(O)(=O)C1=CC(O)=CC(Cl)=C1
CAS DataBase Reference :53984-36-4
Safety Information
| Symbol(GHS): |
 
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
GPR81, also known as hydroxycarboxylic acid receptor 1 (HCAR1), is a recently de-orphanized receptor that is activated by lactic acid (EC50 ~ 1.5 mM) but not by other hydroxycarboxylic acids. 3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 = 16 μM) that is inactive against the related GPR109a (HCAR2) receptor. It is similarly effective at GPR81 receptors from a variety of mammalian species and is bioavailable, stimulating lipolysis (increased serum free fatty acids) in mice fed high fat chow for 10 weeks. 3-chloro-5-hydroxy BA, like lactate, blocks basal ghrelin secretion by primary gastric mucosal cells.More related product prices
5-CHLOROVANILLIC ACIDRelated product price
-
5-CHLOROVANILLIC ACID
$10-1387.39 -
82477-67-6
$7-1998 -
2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
$18-1793
Suppliers and manufacturers
Beyond Pharmaceutical Co., Ltd
J & K SCIENTIFIC LTD.
Yangzhou Siyu Chemical Co.,Ltd.
TCI (Shanghai) Development Co., Ltd.
Shandong Xiya Chemical Co., Ltd
Wuhan ariel chemical Co., LTD.
Wuhan Haizheng Industry & Trade Development Co. Ltd
Shanghai Topbiochem Technology Co., Ltd
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
TOKYO CHEMICAL INDUSTRY CO., LTD.