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ChemicalBook >> CAS DataBase List >> 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride

6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride

6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride price.
  • $12 - $1800
  • Product name: 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride
  • CAS: 72873-74-6
  • MF: C16H12FN3S
  • MW: 297.35
  • EINECS:
  • MDL Number:MFCD00869367
  • Synonyms:6-(4-FLUOROPHENYL)-5-(4-PYRIDYL)-2,3-DIHYDROIMIDAZO[2,1-B]-THIAZOLE;6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PRIDYL)IMIDAZO-[2,1,B]-THAIZOLE;6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDYL)IMIDAZO[2,1-B]THIAZOLE;SKF-86002;SKF 86002 DIHYDROCHLORIDE;6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole;4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene;5-(4-Pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo[2,1-b]thiazole
Price58 Properties Safety Information Description
58 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 2mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 10mM*1mLinDMSO
  • 10mg
  • 25mg
  • 50mg
  • 50.00mg
  • 100.00mg
  • 100MG
  • 250mg
  • 250.00mg
  • 1G
  • Manufactureraablocks
  • Product numberAA005E4Z
  • Product descriptionSKF-86002 98%
  • Packaging1mg
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005E4Z
  • Product descriptionSKF-86002 98%
  • Packaging2mg
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005E4Z
  • Product descriptionSKF-86002 98%
  • Packaging5mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005E4Z
  • Product descriptionSKF-86002 98%
  • Packaging10mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005E4Z
  • Product descriptionSKF-86002 98%
  • Packaging25mg
  • Price$34
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM22581
  • Product descriptionSKF-86002 98%
  • Packaging100MG
  • Price$225
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM22581
  • Product descriptionSKF-86002 98%
  • Packaging1G
  • Price$1125
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1314AC
  • Product description6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b]thiazole
  • Packaging100mg
  • Price$278
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging1g
  • Price$554
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging250mg
  • Price$206
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging25mg
  • Price$43
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging50mg
  • Price$72
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging5mg
  • Price$23
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging10mg
  • Price$28
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging1mg
  • Price$15
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98%
  • Packaging2mg
  • Price$18
  • Updated2026-06-05
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005E4Z SKF-86002 98% 1mg $12 2026-05-28 Buy
aablocks AA005E4Z SKF-86002 98% 2mg $15 2026-05-28 Buy
aablocks AA005E4Z SKF-86002 98% 5mg $19 2026-05-28 Buy
aablocks AA005E4Z SKF-86002 98% 10mg $23 2026-05-28 Buy
aablocks AA005E4Z SKF-86002 98% 25mg $34 2026-05-28 Buy
ACHEMBLOCK M22581 SKF-86002 98% 100MG $225 2026-05-27 Buy
ACHEMBLOCK M22581 SKF-86002 98% 1G $1125 2026-05-27 Buy
AK Scientific 1314AC 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b]thiazole 100mg $278 2021-12-16 Buy
Ambeed A251928 SKF-86002 98% 1g $554 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 250mg $206 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 25mg $43 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 50mg $72 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 5mg $23 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 10mg $28 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 1mg $15 2026-06-05 Buy
Ambeed A251928 SKF-86002 98% 2mg $18 2026-06-05 Buy
Next Last

Properties

Melting point :189-190 °C(lit.)
Boiling point :476.1±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: 9 mg/mL, soluble
form :solid
pka :4.36±0.10(Predicted)
color :off-white
InChI :InChI=1S/C16H12FN3S/c17-13-3-1-11(2-4-13)14-15(12-5-7-18-8-6-12)20-9-10-21-16(20)19-14/h1-8H,9-10H2
InChIKey :YOELZIQOLWZLQC-UHFFFAOYSA-N
SMILES :S1CCN2C(C3C=CN=CC=3)=C(C3=CC=C(F)C=C3)N=C12

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SKF 86002 is a bicyclic imidazole that specifically inhibits p38 MAP kinase, and is also described as a cytokine-suppressant and an anti-inflammatory compound. SKF 86002 has been shown to inhibit Cox (cyclooxygenase) activity and 5-LO (5-lipoxygenase). Osteoblastic cell studies report that SKF 86002 inhibits the production of IL-6. SKF 86002 has been shown to block the activation of TNF-translation and potently inhibit IL-1.

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Suppliers and manufacturers

Angel Pharmatech, Ltd. Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd. Syntechem Co.,Ltd Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Haoyuan Chemexpress Co., Ltd. LETOPHARM LIMITED Shanghai Lollane Biological Technology Co.,Ltd. EMMX Biotechnology LLC