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ChemicalBook >> CAS DataBase List >> 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione price.
  • $12 - $650
  • Product name: 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione
  • CAS: 764667-64-3
  • MF: C14H11F3O5
  • MW: 316.23
  • EINECS:
  • MDL Number:MFCD12407134
  • Synonyms:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione;5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-1,3-dioxane-4,6-dion;5-[1-hydroxy-2-92,4,5-trifluorophenyl0ethylidene]-2,2-dimethyl;1,3-Dioxane-4,6-dione,5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-;5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)-4,6-dionethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione;5-(1-Hydroxy-2-(2,4,5-trifluorophenyl);ethylidene);Sitagliptin Impurity 96
Price23 Properties Safety Information Description
23 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Ambeed
  • Chemenu
  • Crysdot
  • Medical Isotopes, Inc.
  • Synthonix
  • TRC
Package
  • 100mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • Manufactureraablocks
  • Product numberAA005BME
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging1g
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BME
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging5g
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BME
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging10g
  • Price$60
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BME
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging25g
  • Price$119
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ1748
  • Product description5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
  • Packaging1g
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA408083
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging10g
  • Price$60
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA408083
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging5g
  • Price$40
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA408083
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging1g
  • Price$13
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA408083
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging25g
  • Price$125
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA408083
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging100g
  • Price$450
  • Updated2026-06-05
  • Buy
  • ManufacturerChemenu
  • Product numberCM181663
  • Product description5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging10g
  • Price$87
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM181663
  • Product description5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging25g
  • Price$176
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM181663
  • Product description5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging5g
  • Price$52
  • Updated2026-05-26
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12035301
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging25g
  • Price$166
  • Updated2026-05-27
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number59081
  • Product description5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
  • Packaging1g
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerSynthonix
  • Product numberH57534
  • Product description5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%
  • Packaging25g
  • Price$420
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005BME 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 1g $12 2026-05-28 Buy
aablocks AA005BME 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 5g $36 2026-05-28 Buy
aablocks AA005BME 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 10g $60 2026-05-28 Buy
aablocks AA005BME 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 25g $119 2026-05-28 Buy
AK Scientific Z1748 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 1g $71 2021-12-16 Buy
Ambeed A408083 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 10g $60 2026-06-05 Buy
Ambeed A408083 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 5g $40 2026-06-05 Buy
Ambeed A408083 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 1g $13 2026-06-05 Buy
Ambeed A408083 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 25g $125 2026-06-05 Buy
Ambeed A408083 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 100g $450 2026-06-05 Buy
Chemenu CM181663 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 10g $87 2026-05-26 Buy
Chemenu CM181663 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 25g $176 2026-05-26 Buy
Chemenu CM181663 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 5g $52 2026-05-26 Buy
Crysdot CD12035301 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 25g $166 2026-05-27 Buy
Medical Isotopes, Inc. 59081 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 1g $650 2021-12-16 Buy
Synthonix H57534 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97% 25g $420 2026-05-06 Buy
Next Last

Properties

Melting point :117 °C (decomp)
Boiling point :489.0±45.0 °C(Predicted)
Density :1.462±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
pka :4.50±1.00(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).

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Sitagliptin Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate 243139-71-1 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE 3-OXO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID METHYL ESTER 762240-92-6 762240-99-3 Sitagliptin Defuoro IMpurity 3 2,4,5-Trifluorophenylacetic acid 658-93-5 Ethyl trifluoroacetate 81228-09-3 85068-27-5 Sitagliptin phosphate N'-[(2Z)-Piperazin-2-ylidene]trifluoroacetohydrazide 1204818-19-8 Sodium octadecyl fumarate 165047-24-5 2,2-Dimethyl-1,3-dioxane-4,6-dione VINYLIDENE CHLORIDE

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. Xinxiang JuYuan Biological Technology Co., Ltd. Chemsky（shanghai）International Co.,Ltd. Bide Pharmatech Ltd. Wuxi Zhongkun Biochemical Technology Co., Ltd. Shanghai YuLue Chemical Co., Ltd. Shanghai Kewel Chemical Co., Ltd. Nanjing Chalf-Pharm Technology Co., Ltd. Chizhou Kailong Import and Export Trade Co., Ltd. Nanjing XiZe Biotechnology CO., Ltd.