(4Z)-7-[(rel-1S,2s,5r)-5-((1,1'-biphenyl-4-yl)methoxy)-2-(4-morpholinyl)-3-oxocyclopentyl]-4-heptenoic acid calcium salt
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- $91 - $1263
- Product name: (4Z)-7-[(rel-1S,2s,5r)-5-((1,1'-biphenyl-4-yl)methoxy)-2-(4-morpholinyl)-3-oxocyclopentyl]-4-heptenoic acid calcium salt
- CAS: 81496-19-7
- MF: C29H37CaNO5
- MW: 519.7
- EINECS:
- MDL Number:MFCD05665139
- Synonyms:AH23848 CALCIUM SALT;AH23848 hemicalcium salt;COFQPJQSNPAAKY-LCCMWPRESA-M;(4Z)-7-[(rel-1S,2S,5R)-5-((1,1′-Biphenyl-4-yl)methoxy)-2-(4-morpholinyl)-3-oxocyclopentyl]- 4-heptenoic acid hemicalcium salt;(4Z)-7-[(rel-1S,2s,5r)-5-((1,1'-biphenyl-4-yl)methoxy)-2-(4-morpholinyl)-3-oxocyclopentyl]-4-heptenoic acid calcium salt
13 prices
Selected condition:
Brand
- aablocks
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- Manufactureraablocks
- Product numberAA00G5LF
- Product descriptionAH 23848 (calcium salt) ≥90%
- Packaging5mg
- Price$293
- Updated2026-05-28
- Buy
- ManufacturerApexBio Technology
- Product numberC5649
- Product descriptionAH 23848 (calcium salt)
- Packaging1mg
- Price$120
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5649
- Product descriptionAH 23848 (calcium salt)
- Packaging10mg
- Price$662
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5649
- Product descriptionAH 23848 (calcium salt)
- Packaging5mg
- Price$360
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5649
- Product descriptionAH 23848 (calcium salt)
- Packaging25mg
- Price$1263
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number19023
- Product descriptionAH 23848 (calcium salt) ≥90%
- Packaging10mg
- Price$539
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number19023
- Product descriptionAH 23848 (calcium salt) ≥90%
- Packaging1mg
- Price$91
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number19023
- Product descriptionAH 23848 (calcium salt) ≥90%
- Packaging25mg
- Price$739
- Updated2023-01-06
- Buy
- ManufacturerCayman Chemical
- Product number19023
- Product descriptionAH 23848 (calcium salt) ≥90%
- Packaging5mg
- Price$293
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0082846
- Product descriptionAH23848 hemicalcium salt 97.0%
- Packaging5mg
- Price$742
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0082846
- Product descriptionAH23848 hemicalcium salt 97.0%
- Packaging10mg
- Price$1192
- Updated2026-06-04
- Buy
- ManufacturerSigma-Aldrich
- Product numberA8227
- Product descriptionAH23848 hemicalcium salt ≥90% (HPLC), powder
- Packaging25mg
- Price$1130
- Updated2026-04-30
- Buy
- ManufacturerSigma-Aldrich
- Product numberA8227
- Product descriptionAH23848 hemicalcium salt ≥90% (HPLC), powder
- Packaging5mg
- Price$326
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00G5LF | AH 23848 (calcium salt) ≥90% | 5mg | $293 | 2026-05-28 | Buy |
| ApexBio Technology | C5649 | AH 23848 (calcium salt) | 1mg | $120 | 2026-05-06 | Buy |
| ApexBio Technology | C5649 | AH 23848 (calcium salt) | 10mg | $662 | 2026-05-06 | Buy |
| ApexBio Technology | C5649 | AH 23848 (calcium salt) | 5mg | $360 | 2026-05-06 | Buy |
| ApexBio Technology | C5649 | AH 23848 (calcium salt) | 25mg | $1263 | 2026-05-06 | Buy |
| Cayman Chemical | 19023 | AH 23848 (calcium salt) ≥90% | 10mg | $539 | 2026-04-30 | Buy |
| Cayman Chemical | 19023 | AH 23848 (calcium salt) ≥90% | 1mg | $91 | 2026-04-30 | Buy |
| Cayman Chemical | 19023 | AH 23848 (calcium salt) ≥90% | 25mg | $739 | 2023-01-06 | Buy |
| Cayman Chemical | 19023 | AH 23848 (calcium salt) ≥90% | 5mg | $293 | 2026-04-30 | Buy |
| ChemScene | CS-0082846 | AH23848 hemicalcium salt 97.0% | 5mg | $742 | 2026-06-04 | Buy |
| ChemScene | CS-0082846 | AH23848 hemicalcium salt 97.0% | 10mg | $1192 | 2026-06-04 | Buy |
| Sigma-Aldrich | A8227 | AH23848 hemicalcium salt ≥90% (HPLC), powder | 25mg | $1130 | 2026-04-30 | Buy |
| Sigma-Aldrich | A8227 | AH23848 hemicalcium salt ≥90% (HPLC), powder | 5mg | $326 | 2026-04-30 | Buy |
Properties
storage temp. :-20°C
solubility :DMSO: 18 mg/mL at ≤60 °C
form :solid
color :off-white
InChIKey :JDEBIDDIERGZQY-XVFRBOAOSA-L
SMILES :O=C(C[C@@H](OCC1=CC=C(C2=CC=CC=C2)C=C1)[C@H]3CC/C=C\CCC(O[Ca]OC(CC/C=C\CC[C@@H]4[C@H](OCC5=CC=C(C6=CC=CC=C6)C=C5)CC([C@H]4N7CCOCC7)=O)=O)=O)[C@H]3N8CCOCC8
solubility :DMSO: 18 mg/mL at ≤60 °C
form :solid
color :off-white
InChIKey :JDEBIDDIERGZQY-XVFRBOAOSA-L
SMILES :O=C(C[C@@H](OCC1=CC=C(C2=CC=CC=C2)C=C1)[C@H]3CC/C=C\CCC(O[Ca]OC(CC/C=C\CC[C@@H]4[C@H](OCC5=CC=C(C6=CC=CC=C6)C=C5)CC([C@H]4N7CCOCC7)=O)=O)=O)[C@H]3N8CCOCC8
Safety Information
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Description
Thromboxane (TXA2) activates the T prostanoid (TP) receptor. Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. AH-23848 is a dual antagonist of TP and EP4 receptors. It originally was found to inhibit TXA2-induced platelet aggregation (IC50 = 0.26 μM) and the contraction of human bronchial smooth muscle induced by the TP agonist U-46619. AH-23848 was subsequently demonstrated to impair PGE2-mediated relaxation of piglet saphenous vein by antagonizing the PGE2 receptor EP4. By inhibiting EP4, it likewise suppresses serum-induced cAMP generation, cyclin A synthesis, and the proliferation of fibroblasts, as well as reduces metastasis in a mouse model of metastatic breast cancer.Related product price
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