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ChemicalBook >> CAS DataBase List >> 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione

5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione

5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione price.
  • $7 - $2544
  • Product name: 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
  • CAS: 830346-48-0
  • MF: C13H9BrF4N2O2
  • MW: 381.12
  • EINECS:
  • MDL Number:MFCD12546646
  • Synonyms:5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione;Elagolix Impurity 19;5-bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-4-hydroxy-6-methylpyrimidin-2(1H)-one;1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione;1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione;1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-bromo-6-methylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-;5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
Price28 Properties Safety Information Description
28 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • BLDpharm
  • Chemenu
  • ChemScene
  • Crysdot
  • Synthonix
  • TRC
Package
  • 5MG
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • 1000g
  • Manufactureraablocks
  • Product numberAA00G81Q
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95%
  • Packaging25g
  • Price$48
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G81Q
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95%
  • Packaging50g
  • Price$94
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G81Q
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95%
  • Packaging5g
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G81Q
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 98%
  • Packaging1g
  • Price$7
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number9860CS
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione
  • Packaging5g
  • Price$492
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA521045
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95%
  • Packaging5g
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA521045
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95%
  • Packaging1g
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0620593
  • Product description5-BROMO-1-([2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL]METHYL)-6-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 95.00%
  • Packaging5MG
  • Price$459.24
  • Updated2021-12-16
  • Buy
  • ManufacturerBLDpharm
  • Product numberBD303941
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+%
  • Packaging25g
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerBLDpharm
  • Product numberBD303941
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+%
  • Packaging250mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerBLDpharm
  • Product numberBD303941
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+%
  • Packaging1g
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerBLDpharm
  • Product numberBD303941
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+%
  • Packaging5g
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerBLDpharm
  • Product numberBD303941
  • Product description5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+%
  • Packaging100g
  • Price$1103
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105031
  • Product description5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98%
  • Packaging1000g
  • Price$2544
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105031
  • Product description5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98%
  • Packaging25g
  • Price$109
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM105031
  • Product description5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98%
  • Packaging100g
  • Price$353
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00G81Q 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95% 25g $48 2026-05-28 Buy
aablocks AA00G81Q 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95% 50g $94 2026-05-28 Buy
aablocks AA00G81Q 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95% 5g $23 2026-05-28 Buy
aablocks AA00G81Q 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 98% 1g $7 2026-05-28 Buy
AK Scientific 9860CS 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 5g $492 2021-12-16 Buy
Ambeed A521045 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95% 5g $97 2021-12-16 Buy
Ambeed A521045 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95% 1g $29 2021-12-16 Buy
American Custom Chemicals Corporation HCH0620593 5-BROMO-1-([2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL]METHYL)-6-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 95.00% 5MG $459.24 2021-12-16 Buy
BLDpharm BD303941 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+% 25g $334 2021-12-16 Buy
BLDpharm BD303941 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+% 250mg $13 2021-12-16 Buy
BLDpharm BD303941 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+% 1g $29 2021-12-16 Buy
BLDpharm BD303941 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+% 5g $98 2021-12-16 Buy
BLDpharm BD303941 5-Bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 95+% 100g $1103 2021-12-16 Buy
Chemenu CM105031 5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98% 1000g $2544 2021-12-16 Buy
Chemenu CM105031 5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98% 25g $109 2026-05-26 Buy
Chemenu CM105031 5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98% 100g $353 2026-05-26 Buy
Next Last

Properties

Melting point :>230°C (dec.)
Density :1.684±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka :7.83±0.40(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C13H9BrF4N2O2/c1-6-10(14)11(21)19-12(22)20(6)5-7-8(13(16,17)18)3-2-4-9(7)15/h2-4H,5H2,1H3,(H,19,21,22)
InChIKey :RDQPTRWUBKZZFJ-UHFFFAOYSA-N
SMILES :C1(=O)N(CC2=C(C(F)(F)F)C=CC=C2F)C(C)=C(Br)C(=O)N1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.

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Suppliers and manufacturers

Hangzhou Cheminspire Technology Co., Ltd. ChengDu TongChuangYuan Pharmaceutical Co.Ltd Adamas Reagent, Ltd. Shanghai Boc Chemical Co.,Ltd T&W GROUP Suzhou Sino Rare Chemical Co., Ltd. Bide Pharmatech Ltd. Chengdu Climb Pharmaceutical Technology Co., Ltd. Shanghai Kewel Chemical Co., Ltd. SanoChem (Chengdu) Tech. Co., Ltd.