AGM-1470
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- $61 - $14980
- Product name: AGM-1470
- CAS: 129298-91-5
- MF: C19H28ClNO6
- MW: 401.88
- EINECS:
- MDL Number:MFCD00870281
- Synonyms:NSC642492;O-(chloroacetylcarbamoyl)fumagillol;O-(CHLOROACETYLCARBAMOYL)FUMAGILLOLTNP-470 AGM-1470;[(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] N-(2-chloroacetyl)carbamate;AGM-1470;Carbamic acid, (chloroacetyl)-, (3R,4S,5S,6R)-5-methoxy-4-[ (2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester;Tnp-470;N-(2-Chloroacetyl)carbamicacid(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-ylester
42 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 2.5g
- 10mM*1mLinDMSO(Solidorliquid+Solvent)
- 5g
- 10g
- 1 mg
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA000YZD
- Product descriptionNsc642492 ≥98%
- Packaging5mg
- Price$101
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YZD
- Product descriptionNsc642492 ≥98%
- Packaging10mg
- Price$191
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YZD
- Product descriptionNsc642492 ≥98%
- Packaging25mg
- Price$451
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product number7768BA
- Product descriptionO-(Chloroacetylcarbamoyl)fumagillol
- Packaging10mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009209
- Product descriptionTNP-470 95.00%
- Packaging10MG
- Price$726.44
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging25mg
- Price$742
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging10mg
- Price$346
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging5mg
- Price$182
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging10mM*1mLinDMSO(Solution)
- Price$183
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging5mg
- Price$167
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging10mM*1mLinDMSO(Solidorliquid+Solvent)
- Price$173
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging1mg
- Price$84
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging10mg
- Price$266
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberEFA29891
- Product descriptionTNP-470
- Packaging25mg
- Price$1060.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberEFA29891
- Product descriptionTNP-470
- Packaging50mg
- Price$1475
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberEFA29891
- Product descriptionTNP-470
- Packaging100mg
- Price$2360
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000YZD | Nsc642492 ≥98% | 5mg | $101 | 2026-05-25 | Buy |
| aablocks | AA000YZD | Nsc642492 ≥98% | 10mg | $191 | 2026-05-25 | Buy |
| aablocks | AA000YZD | Nsc642492 ≥98% | 25mg | $451 | 2026-05-25 | Buy |
| AK Scientific | 7768BA | O-(Chloroacetylcarbamoyl)fumagillol | 10mg | $302 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009209 | TNP-470 95.00% | 10MG | $726.44 | 2021-12-16 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 25mg | $742 | 2026-05-06 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 10mg | $346 | 2026-05-06 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 5mg | $182 | 2026-05-06 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 10mM*1mLinDMSO(Solution) | $183 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 5mg | $167 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 10mM*1mLinDMSO(Solidorliquid+Solvent) | $173 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 1mg | $84 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 10mg | $266 | 2026-05-26 | Buy |
| Biosynth | EFA29891 | TNP-470 | 25mg | $1060.5 | 2026-06-04 | Buy |
| Biosynth | EFA29891 | TNP-470 | 50mg | $1475 | 2026-06-04 | Buy |
| Biosynth | EFA29891 | TNP-470 | 100mg | $2360 | 2026-06-04 | Buy |
Properties
Melting point :90-93°C
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
form :White to light yellow solid
pka :7.19±0.46(Predicted)
color :White to Pale Yellow Waxy
Stability :Hygroscopic
InChIKey :MSHZHSPISPJWHW-PVDLLORBSA-N
SMILES :ClCC(=O)NC(=O)O[C@H]1[C@H]([C@@H]([C@]3(OC3)CC1)[C@]2(O[C@@H]2CC=C(C)C)C)OC
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
form :White to light yellow solid
pka :7.19±0.46(Predicted)
color :White to Pale Yellow Waxy
Stability :Hygroscopic
InChIKey :MSHZHSPISPJWHW-PVDLLORBSA-N
SMILES :ClCC(=O)NC(=O)O[C@H]1[C@H]([C@@H]([C@]3(OC3)CC1)[C@]2(O[C@@H]2CC=C(C)C)C)OC
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
TNP-470 is a synthetic analog of fumagillin that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2; IC50 = 2 μM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo. It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and microsporidiosis.More related product prices
Methyl acetate Styrene oxide Tribenuron methyl Methyl salicylate Kresoxim-methyl 74223-64-6 ETHYLENE OXIDE Methyl bromideRelated product price
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Methyl acetate
$7.62-1334.03 -
Sineptina
$17-1177.83 -
Styrene oxide
$7.62-5197.5
Suppliers and manufacturers
3B Pharmachem (Wuhan) International Co.,Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Sigma-Aldrich
Hubei Yangxin Medical Technology Co., Ltd.
Jinan Yaoyan Pharmaceutical Co., Ltd.
Shanghai Jizhi Biochemical Technology Co. Ltd.
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
