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ChemicalBook >> CAS DataBase List >> AKTI-1/2

AKTI-1/2

AKTI-1/2 price.
  • $29 - $2200
  • Product name: AKTI-1/2
  • CAS: 612847-09-3
  • MF: C34H29N7O
  • MW: 551.64
  • EINECS:1592732-453-0
  • MDL Number:MFCD09026909
  • Synonyms:3-[1-[[4-(7-phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one;Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem;CS-1595;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-on;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-γ],guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-iMidazo[4,5-g]quinoxalin-7-yl)phenyl]Methyl]-4-piperidinyl]-
Price65 Properties Safety Information Description
65 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 10mM(in 1mL DMSO)
  • 500μg
  • 2mg
  • 2.5MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO
  • 100mg
  • 250mg
  • 1g
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII ≥98%
  • Packaging1mg
  • Price$61
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII
  • Packaging2mg
  • Price$69
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII ≥97%
  • Packaging5mg
  • Price$90
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII
  • Packaging10mg
  • Price$144
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII
  • Packaging25mg
  • Price$243
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII
  • Packaging50mg
  • Price$338
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EC9W
  • Product descriptionAKT inhibitor VIII
  • Packaging100mg
  • Price$476
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230492
  • Product descriptionAKT Inhibitor VIII 98%
  • Packaging25MG
  • Price$330
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230492
  • Product descriptionAKT Inhibitor VIII 98%
  • Packaging10MG
  • Price$185
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230492
  • Product descriptionAKT Inhibitor VIII 98%
  • Packaging100MG
  • Price$680
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX2144
  • Product descriptionAKT Inhibitor VIII
  • Packaging250mg
  • Price$1454
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000362
  • Product descriptionAKTI-1/2 INHIBITOR 95.00%
  • Packaging2.5MG
  • Price$715
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000362
  • Product descriptionAKTI-1/2 INHIBITOR 95.00%
  • Packaging25MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000362
  • Product descriptionAKTI-1/2 INHIBITOR 95.00%
  • Packaging1MG
  • Price$240.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3149
  • Product descriptionAKT inhibitor VIII
  • Packaging25mg
  • Price$385
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3149
  • Product descriptionAKT Inhibitor VIII
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00EC9W AKT inhibitor VIII ≥98% 1mg $61 2026-05-28 Buy
aablocks AA00EC9W AKT inhibitor VIII 2mg $69 2026-05-28 Buy
aablocks AA00EC9W AKT inhibitor VIII ≥97% 5mg $90 2026-05-28 Buy
aablocks AA00EC9W AKT inhibitor VIII 10mg $144 2026-05-28 Buy
aablocks AA00EC9W AKT inhibitor VIII 25mg $243 2026-05-28 Buy
aablocks AA00EC9W AKT inhibitor VIII 50mg $338 2026-05-28 Buy
aablocks AA00EC9W AKT inhibitor VIII 100mg $476 2026-05-28 Buy
ACHEMBLOCK Y230492 AKT Inhibitor VIII 98% 25MG $330 2026-05-27 Buy
ACHEMBLOCK Y230492 AKT Inhibitor VIII 98% 10MG $185 2026-05-27 Buy
ACHEMBLOCK Y230492 AKT Inhibitor VIII 98% 100MG $680 2026-05-27 Buy
AK Scientific X2144 AKT Inhibitor VIII 250mg $1454 2021-12-16 Buy
American Custom Chemicals Corporation INB0000362 AKTI-1/2 INHIBITOR 95.00% 2.5MG $715 2021-12-16 Buy
American Custom Chemicals Corporation INB0000362 AKTI-1/2 INHIBITOR 95.00% 25MG $1963.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0000362 AKTI-1/2 INHIBITOR 95.00% 1MG $240.45 2021-12-16 Buy
ApexBio Technology A3149 AKT inhibitor VIII 25mg $385 2026-05-06 Buy
ApexBio Technology A3149 AKT Inhibitor VIII 25mg $350 2021-12-16 Buy
Next Last

Properties

Melting point :242-245°C (dec.)
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
InChIKey :BIWGYFZAEWGBAL-UHFFFAOYSA-N
SMILES :N6(CCC(CC6)[n]7c8c(nc7O)cccc8)Cc1ccc(cc1)c2nc3c(nc2c5ccccc5)cc4[nH]cnc4c3
CAS DataBase Reference :612847-09-3

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 μM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin regulation of forkhead box 01 activity at 1 μM in rat hepatoma cells.

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Suppliers and manufacturers

career henan chemical co
AKTI-1/2
$2.00 /1kg
AKTI-1/2 CAS:612847-09-3
TargetMol Chemicals Inc.
AKT inhibitor VIII
$61.00 /2mg
AKT inhibitor VIII CAS:612847-09-3
ATK CHEMICAL COMPANY LIMITED
Jinan Carbotang Biotech Co.,Ltd.
CONIER CHEM AND PHARMA LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.