Amifostine
|
- $34 - $2000
- Product name: Amifostine
- CAS: 20537-88-6
- MF: C5H15N2O3PS
- MW: 214.22
- EINECS:633-786-4
- MDL Number:MFCD00233058
- Synonyms:Ethyol;γphos;Fosteamine;2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;Ethiotas;S-2-[(3-Aminopropyl)amino]ethanethiol dihydrogen phosphate ester;Amifostine,2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;AMifostine anhydrous
14 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- AvaChem
- ChemScene
- Medical Isotopes, Inc.
- Tocris
- TRC
Package
- 100
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- 5g
- Manufactureraablocks
- Product numberAA0029YA
- Product descriptionAmifostine 98%(HPLC)
- Packaging5mg
- Price$53
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA0029YA
- Product descriptionAmifostine 98%(HPLC)
- Packaging10mg
- Price$88
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA0029YA
- Product descriptionAmifostine 98%(HPLC)
- Packaging25mg
- Price$168
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA0029YA
- Product descriptionAmifostine 98%(HPLC)
- Packaging50mg
- Price$318
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA0029YA
- Product descriptionAmifostine 98%(HPLC)
- Packaging100mg
- Price$472
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH037
- Product descriptionAmifostine
- Packaging5mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2611
- Product descriptionAmifostine
- Packaging100mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2611
- Product descriptionAmifostine
- Packaging1g
- Price$259
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2611
- Product descriptionAmifostine
- Packaging5g
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2875
- Product descriptionAmifostine ≥98.0%
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2875
- Product descriptionAmifostine ≥98.0%
- Packaging50mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number6335
- Product descriptionAmifostine
- Packaging50mg
- Price$2000
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number6655
- Product descriptionAmifostine
- Packaging100
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA576810
- Product descriptionAmifostine
- Packaging100mg
- Price$55
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0029YA | Amifostine 98%(HPLC) | 5mg | $53 | 2021-12-16 | Buy |
| aablocks | AA0029YA | Amifostine 98%(HPLC) | 10mg | $88 | 2021-12-16 | Buy |
| aablocks | AA0029YA | Amifostine 98%(HPLC) | 25mg | $168 | 2021-12-16 | Buy |
| aablocks | AA0029YA | Amifostine 98%(HPLC) | 50mg | $318 | 2021-12-16 | Buy |
| aablocks | AA0029YA | Amifostine 98%(HPLC) | 100mg | $472 | 2021-12-16 | Buy |
| AK Scientific | H037 | Amifostine | 5mg | $34 | 2021-12-16 | Buy |
| AvaChem | 2611 | Amifostine | 100mg | $129 | 2021-12-16 | Buy |
| AvaChem | 2611 | Amifostine | 1g | $259 | 2021-12-16 | Buy |
| AvaChem | 2611 | Amifostine | 5g | $790 | 2021-12-16 | Buy |
| ChemScene | CS-2875 | Amifostine ≥98.0% | 10mg | $65 | 2021-12-16 | Buy |
| ChemScene | CS-2875 | Amifostine ≥98.0% | 50mg | $272 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 6335 | Amifostine | 50mg | $2000 | 2021-12-16 | Buy |
| Tocris | 6655 | Amifostine | 100 | $102 | 2021-12-16 | Buy |
| TRC | A576810 | Amifostine | 100mg | $55 | 2021-12-16 | Buy |
Properties
Melting point :160-1610C
Boiling point :441.7±51.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in Water.
pka :1.28±0.10(Predicted)
form :powder
color :White
Water Solubility :Soluble to 100 mM in water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChI :InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10)
InChIKey :JKOQGQFVAUAYPM-UHFFFAOYSA-N
SMILES :S(P(O)(O)=O)CCNCCCN
CAS DataBase Reference :20537-88-6(CAS DataBase Reference)
Boiling point :441.7±51.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in Water.
pka :1.28±0.10(Predicted)
form :powder
color :White
Water Solubility :Soluble to 100 mM in water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChI :InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10)
InChIKey :JKOQGQFVAUAYPM-UHFFFAOYSA-N
SMILES :S(P(O)(O)=O)CCNCCCN
CAS DataBase Reference :20537-88-6(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Amifostine, an organic thiophosphate, was introduced for the reduction of cisplatin-induced renal toxicity in patients with advanced ovarian cancer. It is also a radio-protective agent. Amifostine is a prodrug which is rapidly dephosphorylated, preferentially in non-tumor tissues to the active thiol. This agent binds to chemotherapeutic drugs and free radicals released by radiotherapy. The protective effect of amifostine was observed in a wide range of normal organs including bone marrow and gastrointestinal mucosa without interfering with the anti-tumor effect of chemohadiotherapy, indicating an increased therapeutic index for existing cancer treatment. Amifostine is also being evaluated as a cytoprotective in other types of tumors including lung, breast, head and neck cancers. It was reported to be a potent mucolytic with potential in cystic fibrosis.Related product price
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Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Hubei Jusheng Technology Co.,Ltd.
Shanghai Longyu Biotechnology Co., Ltd.
CONIER CHEM AND PHARMA LIMITED
Hefei TNJ Chemical Industry Co.,Ltd.
AFINE CHEMICALS LIMITED
