BAY 11-7085
|
- $15 - $5744
- Product name: BAY 11-7085
- CAS: 196309-76-9
- MF: C13H15NO2S
- MW: 249.33
- EINECS:
- MDL Number:MFCD01862602
- Synonyms:BAY 117083 (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile;(2E)-3-[[4-(1,1-DIMETHYLETHYL)PHENYL]SULFONYL]-2-PROPENENITRILE;BAY 11-7085 - CAS 196309-76-9 - Calbiochem;CS-1876;BAY117085;BAY11-7085;BAY 11-7085;BAY-11-7085;BAY 11-7083;(E)-3-(T-BUTYLPHENYLSULFONYL)-2-PROPENENITRILE;(E)3-[(4-T-BUTYLPHENYL)SULFONYL]-2-PROPENENITRILE
66 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 10mM(in1mLDMSO)
- 50mg
- 100mg
- 200mg
- 10mM(in 1mL DMSO)
- 250MG
- 1.00g
- 1G
- 5G
- 5.00g
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98%
- Packaging1mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98%
- Packaging5mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98%
- Packaging10mg
- Price$45
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98%
- Packaging25mg
- Price$57
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product description(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N)
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98%
- Packaging50mg
- Price$96
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98
- Packaging100mg
- Price$186
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product descriptionBay 11-7085 98
- Packaging200mg
- Price$236
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0073SR
- Product description(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N)
- Packaging50mg
- Price$444
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109429
- Product description(E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile 95.00%
- Packaging250MG
- Price$460
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109429
- Product description(E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile 95.00%
- Packaging1G
- Price$1190
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109429
- Product description(E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile 95.00%
- Packaging5G
- Price$4760
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY1192
- Product description(E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile
- Packaging5g
- Price$5744
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000108
- Product descriptionBAY 11-7085 95.00%
- Packaging10MG
- Price$685.21
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000108
- Product descriptionBAY 11-7085 95.00%
- Packaging5MG
- Price$168.3
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3033
- Product descriptionBAY 11-7085
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0073SR | Bay 11-7085 98% | 1mg | $15 | 2026-05-28 | Buy |
| aablocks | AA0073SR | Bay 11-7085 98% | 5mg | $32 | 2026-05-28 | Buy |
| aablocks | AA0073SR | Bay 11-7085 98% | 10mg | $45 | 2026-05-28 | Buy |
| aablocks | AA0073SR | Bay 11-7085 98% | 25mg | $57 | 2026-05-28 | Buy |
| aablocks | AA0073SR | (E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N) | 10mg | $99 | 2021-12-16 | Buy |
| aablocks | AA0073SR | Bay 11-7085 98% | 50mg | $96 | 2026-05-28 | Buy |
| aablocks | AA0073SR | Bay 11-7085 98 | 100mg | $186 | 2026-05-28 | Buy |
| aablocks | AA0073SR | Bay 11-7085 98 | 200mg | $236 | 2026-05-28 | Buy |
| aablocks | AA0073SR | (E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N) | 50mg | $444 | 2021-12-16 | Buy |
| ACHEMBLOCK | U109429 | (E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile 95.00% | 250MG | $460 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109429 | (E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile 95.00% | 1G | $1190 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109429 | (E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile 95.00% | 5G | $4760 | 2026-05-27 | Buy |
| AK Scientific | Y1192 | (E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile | 5g | $5744 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000108 | BAY 11-7085 95.00% | 10MG | $685.21 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000108 | BAY 11-7085 95.00% | 5MG | $168.3 | 2021-12-16 | Buy |
| ApexBio Technology | B3033 | BAY 11-7085 | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
Properties
Melting point :80-82℃
Boiling point :407.1±45.0 °C(Predicted)
Density :1.144
Flash point :200℃
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >25 mg/mL, soluble
form :solid
color :white
Sensitive :Light Sensitive
InChI :1S/C13H15NO2S/c1-13(2,3)11-5-7-12(8-6-11)17(15,16)10-4-9-14/h4-8,10H,1-3H3/b10-4+
InChIKey :VHKZGNPOHPFPER-ONNFQVAWSA-N
SMILES :CC(C)(C)c1ccc(cc1)S(=O)(=O)\C=C\C#N
CAS DataBase Reference :196309-76-9
Boiling point :407.1±45.0 °C(Predicted)
Density :1.144
Flash point :200℃
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >25 mg/mL, soluble
form :solid
color :white
Sensitive :Light Sensitive
InChI :1S/C13H15NO2S/c1-13(2,3)11-5-7-12(8-6-11)17(15,16)10-4-9-14/h4-8,10H,1-3H3/b10-4+
InChIKey :VHKZGNPOHPFPER-ONNFQVAWSA-N
SMILES :CC(C)(C)c1ccc(cc1)S(=O)(=O)\C=C\C#N
CAS DataBase Reference :196309-76-9
Safety Information
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Description
In the classical pathway of NF-κB activation, phosphorylation of the inhibitor of NF-κB (IκBα) releases the inhibitor from NF-κB, allowing IκBα degradation and NF-κB activation and nuclear import. BAY-11-7085 is an irreversible inhibitor of IκBα phosphorylation, preventing activation of NF-κB by cytokines and lipopolysaccharide (IC50 = 10 μM). It blocks gene expression that is regulated through the classical pathway of NF-κB activation and in this way blocks apoptosis, cell adhesion, and inflammation. BAY-11-7085 is also used to study IκBα actions that are independent of NF-κB signaling.Related product price
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