Cepharanthine
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- $5 - $975.45
- Product name: Cepharanthine
- CAS: 481-49-2
- MF: C37H38N2O6
- MW: 606.71
- EINECS:228-085-1
- MDL Number:MFCD00210482
- Synonyms:1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-;Cepharanthine, >=98%;Cepharanthin, 98%, from Stephania japonica (Thunb.) Miers;Cepharanthine|||CEPHARANTHINE;CEPHARANTHIN;CEPHARANTHINE;OXYACANTHAN,6',12'-DIMETHOXY-2,2'-DIMETHYL-6,7-(METHYLLENEBIS (OXY))-;cepharantin
37 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500MG
- 1g
- 10g
- ManufacturerAK Scientific
- Product numberJ54406
- Product descriptionCepharanthine
- Packaging100mg
- Price$43
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging10mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging50mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging100mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging250mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging1g
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001933
- Product descriptionCEPHARANTHINE 95.00%
- Packaging100MG
- Price$583.21
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001933
- Product descriptionCEPHARANTHINE 95.00%
- Packaging500MG
- Price$681.69
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001933
- Product descriptionCEPHARANTHINE 95.00%
- Packaging1G
- Price$975.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2771
- Product descriptionCepharanthine
- Packaging20mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2771
- Product descriptionCepharanthine
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS024273
- Product descriptionCepharanthine 97%
- Packaging50mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS024273
- Product descriptionCepharanthine 97%
- Packaging100mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS024273
- Product descriptionCepharanthine 97%
- Packaging250mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS024273
- Product descriptionCepharanthine 97%
- Packaging1g
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1897
- Product descriptionCepharanthine
- Packaging10mg
- Price$29
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J54406 | Cepharanthine | 100mg | $43 | 2021-12-16 | Buy |
Ambeed | A508305 | Cepharanthine 97% | 10mg | $5 | 2021-12-16 | Buy |
Ambeed | A508305 | Cepharanthine 97% | 50mg | $8 | 2021-12-16 | Buy |
Ambeed | A508305 | Cepharanthine 97% | 100mg | $15 | 2021-12-16 | Buy |
Ambeed | A508305 | Cepharanthine 97% | 250mg | $23 | 2021-12-16 | Buy |
Ambeed | A508305 | Cepharanthine 97% | 1g | $57 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001933 | CEPHARANTHINE 95.00% | 100MG | $583.21 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001933 | CEPHARANTHINE 95.00% | 500MG | $681.69 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001933 | CEPHARANTHINE 95.00% | 1G | $975.45 | 2021-12-16 | Buy |
ApexBio Technology | N2771 | Cepharanthine | 20mg | $40 | 2021-12-16 | Buy |
ApexBio Technology | N2771 | Cepharanthine | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
Arctom | AS024273 | Cepharanthine 97% | 50mg | $8 | 2021-12-16 | Buy |
Arctom | AS024273 | Cepharanthine 97% | 100mg | $15 | 2021-12-16 | Buy |
Arctom | AS024273 | Cepharanthine 97% | 250mg | $23 | 2021-12-16 | Buy |
Arctom | AS024273 | Cepharanthine 97% | 1g | $56 | 2021-12-16 | Buy |
AvaChem | 1897 | Cepharanthine | 10mg | $29 | 2021-12-16 | Buy |
Properties
Melting point :145-155°
alpha :D20 +277° (c = 2 in chloroform)
Boiling point :654.03°C (rough estimate)
Density :1.1761 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DMSO (35 mg/mL) or ethanol (20 mg/mL)
pka :7.61±0.20(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES :C1CC2C=C3OCOC3=C3OC4C(OC)=CC5CCN(C)[C@]([H])(CC6=CC(=C(OC)C=C6)OC6C=CC(C[C@@]([H])(C=23)N1C)=CC=6)C=5C=4
alpha :D20 +277° (c = 2 in chloroform)
Boiling point :654.03°C (rough estimate)
Density :1.1761 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DMSO (35 mg/mL) or ethanol (20 mg/mL)
pka :7.61±0.20(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES :C1CC2C=C3OCOC3=C3OC4C(OC)=CC5CCN(C)[C@]([H])(CC6=CC(=C(OC)C=C6)OC6C=CC(C[C@@]([H])(C=23)N1C)=CC=6)C=5C=4
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and amphipathic and has been reported to decrease the fluidity of biological membranes. It exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models. Cepharanthine can decrease LPS-stimulated expression of TNF-α, IL-6, and IL-1β in macrophages and prevent the activation of NF-κB, ERK, JNK, and p38 MAPK. It has also been shown to inhibit cell and tumor growth, inducing G1 phase cell cycle arrest and apoptosis, and decreasing expression of STAT3, Bcl-xL, c-Myc, and cyclin D1 in osteosarcoma models.Related product price
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