Cilofexor
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- $23 - $3051
- Product name: Cilofexor
- CAS: 1418274-28-8
- MF: C28H22Cl3N3O5
- MW: 586.85
- EINECS:
- MDL Number:MFCD31731099
- Synonyms:Cilofexor;Cilofexor （GS-9674);2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid;GS-9674;GS9674;CILOFEXOR;CS-2761;2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid;4-Pyridinecarboxylic acid, 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-;GS9674,Inhibitor,inhibit,NR1H4,FXR,Cilofexor,PSC,GS 9674,oral,NASH,GS-9674,antifibrotic,nonsteroidal,anti-inflammatory,Autophagy,safety
48 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 2mg
- 200mg
- 500mg
- 1mlx10mM(inDMSO)
- 10mM*1mLinDMSO
- 250mg
- 1g
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mg
- 25mg
- 100mg
- 5mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA01DQ82
- Product description2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99%
- Packaging5mg
- Price$52
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DQ82
- Product description2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99%
- Packaging10mg
- Price$76
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DQ82
- Product description2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99%
- Packaging25mg
- Price$128
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DQ82
- Product description2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99%
- Packaging1mg
- Price$23
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DQ82
- Product description2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99%
- Packaging50mg
- Price$218
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DQ82
- Product description2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid ≥98%
- Packaging100mg
- Price$413
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberS86638
- Product descriptionCilofexor 98%
- Packaging100MG
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS86638
- Product descriptionCilofexor 98%
- Packaging25MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2668DU
- Product descriptionCilofexor
- Packaging5mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging10mg
- Price$251
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging25mg
- Price$456
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging50mg
- Price$684
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$192
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging10mM*1mLinDMSO(Solution)
- Price$203
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging5mg
- Price$157
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-109083
- Product descriptionCilofexor 98.87%
- Packaging100mg
- Price$903
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01DQ82 | 2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99% | 5mg | $52 | 2026-05-29 | Buy |
| aablocks | AA01DQ82 | 2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99% | 10mg | $76 | 2026-05-29 | Buy |
| aablocks | AA01DQ82 | 2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99% | 25mg | $128 | 2026-05-29 | Buy |
| aablocks | AA01DQ82 | 2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99% | 1mg | $23 | 2026-05-29 | Buy |
| aablocks | AA01DQ82 | 2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid 99% | 50mg | $218 | 2026-05-29 | Buy |
| aablocks | AA01DQ82 | 2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid ≥98% | 100mg | $413 | 2026-05-29 | Buy |
| ACHEMBLOCK | S86638 | Cilofexor 98% | 100MG | $450 | 2026-05-27 | Buy |
| ACHEMBLOCK | S86638 | Cilofexor 98% | 25MG | $190 | 2026-05-27 | Buy |
| AK Scientific | 2668DU | Cilofexor | 5mg | $276 | 2021-12-16 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 10mg | $251 | 2026-05-26 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 25mg | $456 | 2026-05-26 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 50mg | $684 | 2026-05-26 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 10mM*1mLinDMSO(Solid+Solvent) | $192 | 2026-05-26 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 10mM*1mLinDMSO(Solution) | $203 | 2026-05-26 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 5mg | $157 | 2026-05-26 | Buy |
| Arctom | HY-109083 | Cilofexor 98.87% | 100mg | $903 | 2026-05-26 | Buy |
Properties
Boiling point :855.5±65.0 °C(Predicted)
Density :1.538±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:32.5(Max Conc. mg/mL);55.38(Max Conc. mM)
form :A crystalline solid
pka :2.10±0.10(Predicted)
color :Off-white to light yellow
InChIKey :KZSKGLFYQAYZCO-UHFFFAOYSA-N
SMILES :C1(N2CC(C3=CC=C(OCC4=C(C5CC5)ON=C4C4=C(Cl)C=CC=C4Cl)C=C3Cl)(O)C2)=NC=CC(C(O)=O)=C1
Density :1.538±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:32.5(Max Conc. mg/mL);55.38(Max Conc. mM)
form :A crystalline solid
pka :2.10±0.10(Predicted)
color :Off-white to light yellow
InChIKey :KZSKGLFYQAYZCO-UHFFFAOYSA-N
SMILES :C1(N2CC(C3=CC=C(OCC4=C(C5CC5)ON=C4C4=C(Cl)C=CC=C4Cl)C=C3Cl)(O)C2)=NC=CC(C(O)=O)=C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). It has FXR agonist activity in a mammalian one hybrid (M1H) assay (EC50 = ≥100 nM).Related product price
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