Cilomilast
|
- $32 - $3176.25
- Product name: Cilomilast
- CAS: 153259-65-5
- MF: C20H25NO4
- MW: 343.42
- EINECS:200-258-5
- MDL Number:MFCD00924373
- Synonyms:4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)cyclohexane-1-carboxylic acid;CS-515;SB 207499 - Cilomilast | Ariflo;4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)-1-cyclohexanecarboxylic acid;Cilomilast, SB 207499, Ariflo;"(cilomilast) 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid";CILOMILAST;Clomilast
29 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 2x5mg
- 25mg
- 50MG
- 100mg
- 1g
- ManufacturerAK Scientific
- Product numberX7566
- Product descriptionCilomilast
- Packaging5mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM1046619
- Product descriptionCILOMELAST 95.00%
- Packaging50MG
- Price$3176.25
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4329
- Product descriptionCilomilast
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4329
- Product descriptionCilomilast
- Packaging10mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1592
- Product descriptionSB207499-Cilomilast|Ariflo 99%
- Packaging2x5mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1592
- Product descriptionSB207499-Cilomilast|Ariflo 99%
- Packaging25mg
- Price$286
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20436
- Product descriptionCilomilast
- Packaging2mg
- Price$281.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20436
- Product descriptionCilomilast
- Packaging5mg
- Price$511
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20436
- Product descriptionCilomilast
- Packaging10mg
- Price$929.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20436
- Product descriptionCilomilast
- Packaging25mg
- Price$1689.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20436
- Product descriptionCilomilast
- Packaging50mg
- Price$3071.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25979
- Product descriptionCilomilast
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25979
- Product descriptionCilomilast
- Packaging5mg
- Price$131
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25979
- Product descriptionCilomilast
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0470
- Product descriptionCilomilast 99.11%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0470
- Product descriptionCilomilast 99.11%
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7566 | Cilomilast | 5mg | $174 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM1046619 | CILOMELAST 95.00% | 50MG | $3176.25 | 2021-12-16 | Buy |
| ApexBio Technology | A4329 | Cilomilast | 5mg | $84 | 2021-12-16 | Buy |
| ApexBio Technology | A4329 | Cilomilast | 10mg | $147 | 2021-12-16 | Buy |
| Axon Medchem | Axon1592 | SB207499-Cilomilast|Ariflo 99% | 2x5mg | $132 | 2021-12-16 | Buy |
| Axon Medchem | Axon1592 | SB207499-Cilomilast|Ariflo 99% | 25mg | $286 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20436 | Cilomilast | 2mg | $281.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20436 | Cilomilast | 5mg | $511 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20436 | Cilomilast | 10mg | $929.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20436 | Cilomilast | 25mg | $1689.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20436 | Cilomilast | 50mg | $3071.5 | 2021-12-16 | Buy |
| Cayman Chemical | 25979 | Cilomilast | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 25979 | Cilomilast | 5mg | $131 | 2024-03-01 | Buy |
| Cayman Chemical | 25979 | Cilomilast | 10mg | $243 | 2024-03-01 | Buy |
| ChemScene | CS-0470 | Cilomilast 99.11% | 5mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-0470 | Cilomilast 99.11% | 10mg | $168 | 2021-12-16 | Buy |
Properties
Melting point :157°C
Boiling point :549.1±50.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.45±0.25(Predicted)
color :white to beige
InChI :InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20+
InChIKey :CFBUZOUXXHZCFB-OYOVHJISSA-N
SMILES :[C@@H]1(C(O)=O)CC[C@](C#N)(C2=CC=C(OC)C(OC3CCCC3)=C2)CC1
Boiling point :549.1±50.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.45±0.25(Predicted)
color :white to beige
InChI :InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20+
InChIKey :CFBUZOUXXHZCFB-OYOVHJISSA-N
SMILES :[C@@H]1(C(O)=O)CC[C@](C#N)(C2=CC=C(OC)C(OC3CCCC3)=C2)CC1
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Cilomilast-d9 is a deuterium-labeled compound that is an inhibitor of phosphodiesterase enzymes, particularly LPDE4 and HPDE4, with IC50 = 100 nM and 120 nM, respectively. These phosphodiesterases are responsible for the hydrolysis of cAMP, a secondary messenger molecule with a variety of roles. Prolonging the lifetime of cAMP has a potentiating effect on signal transduction.Related product price
- Cyclohexane
$10-8580 - 32171-39-4
$26.9-501 - p-Anisidine
$9-4310.36
Suppliers and manufacturers
Hubei xin bonus chemical co. LTD
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Baoji Guokang Healthchem Co., Ltd.
Hefei Hirisun Pharmatech Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited
