EMPA
|
- $57 - $2200
- Product name: EMPA
- CAS: 680590-49-2
- MF: C23H26N4O4S
- MW: 454.54
- EINECS:
- MDL Number:
- Synonyms:N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide;N-ETHYL-2-[(6-METHOXYPYRIDIN-3-YL)-(2-METHYLPHENYL)SULFONYLAMINO]-N-(PYRIDIN-3-YLMETHYL)ACETAMIDE;EMPA, CID 9981404;Acetamide, N-ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-;Hypocretin Receptor,EMPA,Orexin Receptor (OX Receptor),HCRT Receptor,inhibit,Inhibitor;N-Ethyl-2-((N-(6-methoxypyridin-3-yl)-2-methylphenyl)sulfonamido)-N-(pyridin-3-ylmethyl)acetamide;EMPA, 10 mM in DMSO
40 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 002
- 1mg
- 2mg
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 25mg
- 50mg
- 100mg
- 250MG
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging2mg
- Price$73
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging5mg
- Price$99
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging1mg
- Price$58
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging10mg
- Price$143
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging25mg
- Price$243
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging50mg
- Price$354
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FDHA
- Product descriptionN-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide
- Packaging100mg
- Price$521
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203214
- Product descriptionEMPA 98.00%
- Packaging100MG
- Price$530
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203214
- Product descriptionEMPA 98.00%
- Packaging250MG
- Price$905
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4657CR
- Product descriptionEmpa
- Packaging5mg
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0017731
- Product descriptionEMPA 95.00%
- Packaging10MG
- Price$275.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5641
- Product descriptionEMPA
- Packaging10mg
- Price$190
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5641
- Product descriptionEMPA
- Packaging5mg
- Price$126
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5641
- Product descriptionEMPA
- Packaging50mg
- Price$1494
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-108682
- Product descriptionEMPA 99.92%
- Packaging100mg
- Price$720
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-108682
- Product descriptionEMPA 99.92%
- Packaging5mg
- Price$119
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 2mg | $73 | 2026-05-28 | Buy |
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 5mg | $99 | 2026-05-28 | Buy |
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 1mg | $58 | 2026-05-28 | Buy |
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 10mg | $143 | 2026-05-28 | Buy |
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 25mg | $243 | 2026-05-28 | Buy |
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 50mg | $354 | 2026-05-28 | Buy |
| aablocks | AA00FDHA | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)acetamide | 100mg | $521 | 2026-05-28 | Buy |
| ACHEMBLOCK | X203214 | EMPA 98.00% | 100MG | $530 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203214 | EMPA 98.00% | 250MG | $905 | 2026-05-27 | Buy |
| AK Scientific | 4657CR | Empa | 5mg | $214 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0017731 | EMPA 95.00% | 10MG | $275.1 | 2021-12-16 | Buy |
| ApexBio Technology | B5641 | EMPA | 10mg | $190 | 2026-05-06 | Buy |
| ApexBio Technology | B5641 | EMPA | 5mg | $126 | 2026-05-06 | Buy |
| ApexBio Technology | B5641 | EMPA | 50mg | $1494 | 2026-05-06 | Buy |
| Arctom | HY-108682 | EMPA 99.92% | 100mg | $720 | 2026-05-26 | Buy |
| Arctom | HY-108682 | EMPA 99.92% | 5mg | $119 | 2026-05-26 | Buy |
Properties
Boiling point :660.7±65.0 °C(Predicted)
Density :1.280±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
pka :4.77±0.10(Predicted)
color :white to light brown
InChI :1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3
InChIKey :KJPHTXTWFHVJIG-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N(CC(=O)N(CC)Cc3cnccc3)c2cnc(cc2)OC)c1c(cccc1)C
Density :1.280±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
pka :4.77±0.10(Predicted)
color :white to light brown
InChI :1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3
InChIKey :KJPHTXTWFHVJIG-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N(CC(=O)N(CC)Cc3cnccc3)c2cnc(cc2)OC)c1c(cccc1)C
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
EMPA is an orexin 2 receptor (OX2R) antagonist (Ki = 1.1 nM). It is selective for OX2R over OX1R (Ki = 900 nM). EMPA inhibits orexin-A- and orexin-B-induced calcium mobilization (IC50s = 8.8 and 7.9 nM, respectively) and increases orexin-A- and orexin-B-induced inositol phosphate accumulation (EC50s = 1.1 and 2.4 nM, respectively) in CHO(dHFr-) cells expressing recombinant human OX2R. It reduces spontaneous locomotor activity and orexin-B-induced hyperlocomotion in mice when administered at doses ranging between 10 and 300 mg/kg.More related product prices
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride 110-30-5 EMPA SC-51089Related product price
-
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
$114-2400 -
110-30-5
$8-4675 -
EMPA
$57-2200
Suppliers and manufacturers
J & K SCIENTIFIC LTD.
Shanghai TaoSu Biochemical Technology Co., Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.
Bide Pharmatech Ltd.
HangZhou YuHao Chemical Technology Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai Chaolan Chemical Technology Center