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ChemicalBook >> CAS DataBase List >> Epacadostat (INCB024360)

Epacadostat (INCB024360)

Epacadostat (INCB024360) price.
  • $11 - $2822
  • Product name: Epacadostat (INCB024360)
  • CAS: 1204669-58-8
  • MF: C11H13BrFN7O4S
  • MW: 438.23
  • EINECS:
  • MDL Number:MFCD29075639
  • Synonyms:(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(sulfamoylamino)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide;Epacadostat (INCB24360, INCB024360);N-(3-Bromo-4-fluoro-phenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine;INCN024360;(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine;Epacadostat(INCN024360);INCB-24360(INCB-024360);Epacadostat(INCB024360)
Price79 Properties Safety Information Description
79 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 2x25mg
  • 500mg
  • 2g
  • 200mg
  • 50.00g
  • 100.00g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO
  • 250.00g
  • 10mM(1mLinDMSO)
  • 10mM(in1mLDMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99%
  • Packaging1mg
  • Price$11
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99%
  • Packaging2mg
  • Price$13
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99%
  • Packaging5mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99%
  • Packaging10mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99%
  • Packaging50mg
  • Price$70
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95%
  • Packaging100mg
  • Price$96
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95%
  • Packaging250mg
  • Price$140
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95%
  • Packaging1g
  • Price$363
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95%
  • Packaging5g
  • Price$1096
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJF
  • Product description[C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95%
  • Packaging10g
  • Price$1653
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16050
  • Product descriptionIDO inhibitor 1 98%
  • Packaging1G
  • Price$595
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16050
  • Product descriptionIDO inhibitor 1 98%
  • Packaging100MG
  • Price$195
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16050
  • Product descriptionIDO inhibitor 1 98%
  • Packaging25MG
  • Price$65
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3634-M005
  • Product descriptionEpacadostat ≥98%(HPLC)
  • Packaging5mg
  • Price$70
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3634-M025
  • Product descriptionEpacadostat ≥98%(HPLC)
  • Packaging25mg
  • Price$210
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product number3196EM
  • Product descriptionEpacadostat
  • Packaging50mg
  • Price$498
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99% 1mg $11 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99% 2mg $13 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99% 5mg $16 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99% 10mg $23 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 99% 50mg $70 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95% 100mg $96 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95% 250mg $140 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95% 1g $363 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95% 5g $1096 2026-05-28 Buy
aablocks AA008TJF [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide 95% 10g $1653 2026-05-28 Buy
ACHEMBLOCK R16050 IDO inhibitor 1 98% 1G $595 2026-05-27 Buy
ACHEMBLOCK R16050 IDO inhibitor 1 98% 100MG $195 2026-05-27 Buy
ACHEMBLOCK R16050 IDO inhibitor 1 98% 25MG $65 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-3634-M005 Epacadostat ≥98%(HPLC) 5mg $70 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3634-M025 Epacadostat ≥98%(HPLC) 25mg $210 2026-05-06 Buy
AK Scientific 3196EM Epacadostat 50mg $498 2021-12-16 Buy
Next Last

Properties

Melting point :159 - 161°C
Boiling point :700.9±70.0 °C(Predicted)
Density :2.01±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :7.65±0.69(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)
InChIKey :FBKMWOJEPMPVTQ-UHFFFAOYSA-N
SMILES :C(/C1=NON=C1NCCNS(=O)(=O)N)(=N\O)\NC1C=C(Br)C(F)=CC=1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

INCB024360 is an inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1) with an IC50 value of 7.1 nM in HeLa cells that demonstrates little activity against the related enzymes IDO2 or tryptophan 2,3-dioxygenase (TDO). It has been shown to promote T- and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. INCB024360 can also inhibit tumor growth in tumor-bearing mice in a lymphocyte-dependent manner.

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Suppliers and manufacturers

career henan chemical co
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Capot Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED
Zhejiang ZETian Fine Chemicals Co. LTD
Biochempartner
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Hefei Hangang Pharmaceutical Technology Co., Ltd.