Fosaprepitant dimeglumine
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- $5 - $4990
- Product name: Fosaprepitant dimeglumine
- CAS: 265121-04-8
- MF: C30H39F7N5O11P
- MW: 809.63
- EINECS:682-419-4
- MDL Number:MFCD23102059
- Synonyms:Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol;1-Deoxy-1-(MethylaMino)-D-glucitol [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate;1-DEOXY-1-(METHYLAMINO)-D-GLUCITOL [[(2R,3S]-2-[(1R)-1-[3,5-BIS (TRIFLUOROMETHYL)PHENYL] PHENYL]ETHOXY]-(4-FLUOROPHENYL);3-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-phosphinic acid bis(N-Methyl-D-glucaMine) salt;Fosaprepitant dimeglumine, >=99%;Fosaprepitant dimegluminer
70 prices
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Chemtos
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 2g
- 5G
- Manufactureraablocks
- Product numberAA00BF0O
- Product descriptionFosaprepitant dimeglumine 98%（HNMR）
- Packaging5mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF0O
- Product descriptionFosaprepitant dimeglumine 98%（HNMR）
- Packaging50mg
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF0O
- Product descriptionFosaprepitant dimeglumine 98%（HNMR）
- Packaging100mg
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF0O
- Product descriptionFosaprepitant dimeglumine 98%
- Packaging250mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF0O
- Product descriptionFosaprepitant dimeglumine 98%（HNMR）
- Packaging1g
- Price$121
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238363
- Product descriptionFosaprepitant dimeglumine 98%
- Packaging5G
- Price$525
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238363
- Product descriptionFosaprepitant dimeglumine 98%
- Packaging1G
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ11396
- Product descriptionFosaprepitantdimeglumine
- Packaging10mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging5g
- Price$423
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging1g
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging250mg
- Price$47
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging50mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging100mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging5mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging10mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2145
- Product descriptionFosaprepitant dimeglumine salt
- Packaging10mg
- Price$97
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BF0O | Fosaprepitant dimeglumine 98%（HNMR） | 5mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00BF0O | Fosaprepitant dimeglumine 98%（HNMR） | 50mg | $21 | 2026-05-28 | Buy |
| aablocks | AA00BF0O | Fosaprepitant dimeglumine 98%（HNMR） | 100mg | $29 | 2026-05-28 | Buy |
| aablocks | AA00BF0O | Fosaprepitant dimeglumine 98% | 250mg | $44 | 2026-05-28 | Buy |
| aablocks | AA00BF0O | Fosaprepitant dimeglumine 98%（HNMR） | 1g | $121 | 2026-05-28 | Buy |
| ACHEMBLOCK | Z238363 | Fosaprepitant dimeglumine 98% | 5G | $525 | 2026-05-27 | Buy |
| ACHEMBLOCK | Z238363 | Fosaprepitant dimeglumine 98% | 1G | $150 | 2026-05-27 | Buy |
| AK Scientific | J11396 | Fosaprepitantdimeglumine | 10mg | $226 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 5g | $423 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 1g | $126 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 250mg | $47 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 50mg | $19 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 100mg | $28 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 5mg | $6 | 2021-12-16 | Buy |
| Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 10mg | $8 | 2021-12-16 | Buy |
| ApexBio Technology | B2145 | Fosaprepitant dimeglumine salt | 10mg | $97 | 2026-05-06 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form :Powder
pka :Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.
color :White to off-white
optical activity :[α]/D +27 to +34°, c =0.5 in methanol
Water Solubility :H2O: 2mg/mL, clear
InChIKey :UGJUJYSRBQWCEK-QBRZKSSTNA-N
SMILES :FC1=CC=C([C@@H]2N(CCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)CC(NC4=O)=NN4P(O)(O)=O)C=C1.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
solubility :≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form :Powder
pka :Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.
color :White to off-white
optical activity :[α]/D +27 to +34°, c =0.5 in methanol
Water Solubility :H2O: 2mg/mL, clear
InChIKey :UGJUJYSRBQWCEK-QBRZKSSTNA-N
SMILES :FC1=CC=C([C@@H]2N(CCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)CC(NC4=O)=NN4P(O)(O)=O)C=C1.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Fosaprepitant dimeglumine is a water-soluble prodrug form of the neurokinin-1 receptor antagonist aprepitant. Formulations containing fosaprepitant dimeglumine have been used to prevent chemotherapy-induced nausea and vomiting.Related product price
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Suppliers and manufacturers
Changzhou Rokechem Technology Co., Ltd.
Fosaprepitant Dimeglumine
CAS:265121-04-8
Moxin Chemicals
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Lianyungang happen teng technology co., LTD
Fosaprepitant Dimeglumine
CAS:265121-04-8
