ICI 216,140
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- $153 - $984
- Product name: ICI 216,140
- CAS: 124001-41-8
- MF: C45H65N13O8
- MW: 916.08
- EINECS:
- MDL Number:MFCD00153815
- Synonyms:ICI 216,140;(CH3)2CHCO-HIS-TRP-ALA-VAL-D-ALA-HIS-LEU-NHCH3;ICI 216,140 SYNTHETIC >95% POTENT IN VIV O ANTAGO;N-(2-Methyl-1-oxopropyl)-L-His-L-Trp-L-Ala-L-Val-D-Ala-L-His-N-methyl-L-Leu-NH2;(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-(2-methylpropanoylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]propanoyl]amino]-N,4-dimethylpentanamide;m 216140;m216140;m-216140
11 prices
Selected condition：
Brand
- aablocks
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 2.5mg
- 5mg
- Manufactureraablocks
- Product numberAA009FWX
- Product descriptionIci 216140 >98%
- Packaging5mg
- Price$880
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009FWX
- Product descriptionIci 216140 >98%
- Packaging1mg
- Price$369
- Updated2026-05-28
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0004558
- Product descriptionICI 216,140 95.00%
- Packaging1MG
- Price$733.72
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17479
- Product descriptionICI 216140 ≥95%
- Packaging5mg
- Price$759
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17479
- Product descriptionICI 216140 ≥95%
- Packaging500μg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17479
- Product descriptionICI 216140 ≥95%
- Packaging1mg
- Price$275
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0145633
- Product descriptionICI 216140 99.78%
- Packaging1mg
- Price$325
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0145633
- Product descriptionICI 216140 99.78%
- Packaging5mg
- Price$823
- Updated2026-06-04
- Buy
- ManufacturerTRC
- Product numberI163858
- Product descriptionICI216,140
- Packaging2.5mg
- Price$515
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number452181
- Product descriptionICI 216,140
- Packaging1mg
- Price$581
- Updated2026-06-03
- Buy
- ManufacturerUsbiological
- Product number452181
- Product descriptionICI 216,140
- Packaging2.5mg
- Price$984
- Updated2026-06-03
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009FWX | Ici 216140 >98% | 5mg | $880 | 2026-05-28 | Buy |
| aablocks | AA009FWX | Ici 216140 >98% | 1mg | $369 | 2026-05-28 | Buy |
| American Custom Chemicals Corporation | PEP0004558 | ICI 216,140 95.00% | 1MG | $733.72 | 2021-12-16 | Buy |
| Cayman Chemical | 17479 | ICI 216140 ≥95% | 5mg | $759 | 2024-03-01 | Buy |
| Cayman Chemical | 17479 | ICI 216140 ≥95% | 500μg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 17479 | ICI 216140 ≥95% | 1mg | $275 | 2024-03-01 | Buy |
| ChemScene | CS-0145633 | ICI 216140 99.78% | 1mg | $325 | 2026-06-04 | Buy |
| ChemScene | CS-0145633 | ICI 216140 99.78% | 5mg | $823 | 2026-06-04 | Buy |
| TRC | I163858 | ICI216,140 | 2.5mg | $515 | 2021-12-16 | Buy |
| Usbiological | 452181 | ICI 216,140 | 1mg | $581 | 2026-06-03 | Buy |
| Usbiological | 452181 | ICI 216,140 | 2.5mg | $984 | 2026-06-03 | Buy |
Properties
Boiling point :1452.6±65.0 °C(Predicted)
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF:2.0(Max Conc. mg/mL);2.18(Max Conc. mM)
DMSO:2.0(Max Conc. mg/mL);2.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);10.92(Max Conc. mM) form :solid
pka :12.85±0.46(Predicted)
color :white
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF:2.0(Max Conc. mg/mL);2.18(Max Conc. mM)
DMSO:2.0(Max Conc. mg/mL);2.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);10.92(Max Conc. mM) form :solid
pka :12.85±0.46(Predicted)
color :white
Safety Information
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Description
Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. Its three receptors are distributed throughout the central and peripheral nervous system and are involved in gastric acid secretion, emotional response, temperature control, learning, and memory. Neuromedin B and gastrin-releasing peptide (GRP) are mammalian homologs of bombesin. ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50 = 2 nM in vitro). At 2 mg/kg, it can reduce bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been shown to attenuate bombesin-stimulated increases in blood pressure in rats.Related product price
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ICI 216,140
$153-984 -
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Suppliers and manufacturers
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TargetMol Chemicals Inc.
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Shanghai Yifei Biotechnology Co. , Ltd.
